Citation

BibTex format

@article{Albrecht:2016:10.1039/C5NR08634E,
author = {Albrecht, T and Fraccari, R and Ciccarella, P and Bahrami, A and Carminati, M and Ferrari, G},
doi = {10.1039/C5NR08634E},
journal = {Nanoscale},
pages = {7604--7611},
title = {High-speed detection of DNA Translocation in Nanopipettes},
url = {http://dx.doi.org/10.1039/C5NR08634E},
volume = {8},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - We present a high-speed electrical detection scheme based on a custom-designed CMOS amplifier which allows the analysis of DNA translocation in glass nanopipettes on a microsecond timescale. Translocation of different DNA lengths in KCl electrolyte provides a scaling factor of the DNA translocation time equal to p = 1.22, which is different from values observed previously with nanopipettes in LiCl electrolyte or with nanopores. Based on a theoretical model involving electrophoresis, hydrodynamics and surface friction, we show that the experimentally observed range of p-values may be the result of, or at least be affected by DNA adsorption and friction between the DNA and the substrate surface.
AU - Albrecht,T
AU - Fraccari,R
AU - Ciccarella,P
AU - Bahrami,A
AU - Carminati,M
AU - Ferrari,G
DO - 10.1039/C5NR08634E
EP - 7611
PY - 2016///
SN - 2040-3372
SP - 7604
TI - High-speed detection of DNA Translocation in Nanopipettes
T2 - Nanoscale
UR - http://dx.doi.org/10.1039/C5NR08634E
UR - http://hdl.handle.net/10044/1/30408
VL - 8
ER -