Publications since October 2017

Perbellini F, Watson SA, Bardi I, Terracciano CM. Heterocellularity and cellular cross-talk in the cardiovascular system. Frontiers in cardiovascular medicine. Front Cardiovasc Med. 2018 Nov 1;5:143. doi: 10.3389/fcvm.2018.00143. eCollection 2018.

Sparrow AJ, Sievert K, Patel S, Chang YF, Broyles CN, Brook FA, Watkins H, Geeves MA, Redwood CS, Robinson P, Daniels MJ. Measurement of myofilament-localized calcium dynamics in adult cardiomyocytes and the effect of hypertrophic cardiomyopathy mutations. Circulation research. 2019 Apr 12;124(8):1228-39.

Smith JGW, Owen T, Bhagwan JR, Mosqueira D, Scott E, Mannhardt I, Patel A, Barriales-Villa R, Monserrat L, Hansen A, Eschenhagen T, Harding SE, Marston S, Denning C. Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits. Stem Cell Reports. 2018 Nov 13;11(5):1226-1243. doi:10.1016/j.stemcr.2018.10.006. Epub 2018 Nov 1.

Panahi M, Papanikolaou A, Torabi A, Zhang JG, Khan H, Vazir A, Hasham MG, Cleland JGF, Rosenthal NA, Harding SE, Sattler S. Immunomodulatory interventions in myocardial infarction and heart failure: a systematic review of clinical trials and meta-analysis of IL-1 inhibition. Cardiovasc Res. 2018 Sep 1;114(11):1445-1461. doi: 10.1093/cvr/cvy145.

Oldershaw R, Owens WA, Sutherland R, Linney M, Liddle R, Magana L, Lash GE, Gill JH, Richardson G, Meeson A. Human Cardiac-Mesenchymal Stem Cell-Like Cells, a Novel Cell Population with Therapeutic Potential. Stem Cells Dev. 2019 May 1;28(9):593-607. doi: 10.1089/scd.2018.0170. Epub 2019 Apr 3.

Fiedler LR, Chapman K, Xie M, Maifoshie E, Jenkins M, Golforoush PA, Bellahcene M, Noseda M, Faust D, Jarvis A, Newton G, Paiva MA, Harada M, Stuckey DJ, Song W, Habib J, Narasimham P, Aqil R, Sanmugalingam D, Yan R, Pavanello L, Sano M, Wang SC, Sampson RD, Kanayaganam S, Taffet GE, Michael LH, Entman ML, Tan TH, Harding SE, Low CMR, Tralau-Stewart C, Perrior T, Schneider MD. MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo. Cell Stem Cell. 2019 Apr 4;24(4):579-591.e12. doi: 10.1016/j.stem.2019.01.013. Epub 2019 Mar 7. PubMed PMID: 30853557.

Alexander Kondrashov, Minh Duc Hoang, Jamie Bhagwan, Gary Duncan, James Smith, Chris Denning. Simplified footprint-free Cas9/CRISPR editing of cardiac-associated genes in human pluripotent stem cells. Stem Cells & Development. In Press

Barbara Lukasiewicz, Pooja Basnett, Rinat Nigmatullin, Rupy Matharu, Jonathan C. Knowles and Ipsita Roy. Binary Polyhydroxyalkanoate Systems for Soft Tissue Engineering. Acta Biomaterialia, 2018 Apr 15;71:225-234. doi: 10.1016/j.actbio.2018.02.027. Epub 2018 Mar 2.

Chow A, Stuckey DJ, Kidher E, Rocco M, Jabbour RJ, Mansfield CA, Darzi A,Harding SE, Stevens MM, Athanasiou T. Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Encapsulating Bioactive Hydrogels Improve Rat Heart Function Post Myocardial Infarction. Stem Cell Reports. 2017 Nov 14;9(5):1415-1422

Duncan G, Firth K, George V, Staniforth A, Smith G, Denning C. Drug-mediated shortening of action potentials in LQTS hiPSC-cardiomyocytes. Stem Cells & Development. In Press

El Harane, N., Kervadec, A., Bellamy, V., Pidial, L., Neametalla, H.J., Perier, M.C., Lima Correa, B., Thiébault, L., Cagnard, N., Duché, A. and Brunaud, C., 2018. Acellular therapeutic approach for heart failure: in vitro production of extracellular vesicles from human cardiovascular progenitors. European heart journal.

Fedir N Kiskin, C-Hong Chang, Christopher J.Z. Huang, Baraa Kwieder, Christine Cheung, Benjamin J Dunmore, Felipe Serrano, Sanjay Sinha, Nicholas W Morrell, and Amer A Rana. Contributions of BMPR2 Mutations and Extrinsic Factors to Cellular Phenotypes of Pulmonary Arterial Hypertension Revealed by iPSC Modeling. PubMed:29547009

Guex AG, Spicer CD, Armgarth A, Gelmi A, Humphrey EJ, Terracciano CM, Harding S, Stevens MM. Electrospun aniline-tetramer-co-polycaprolactone fibres for
conductive, biodegradable scaffolds. MRS Commun. 2017 Sep;7(3):375-382.

M. Kapnisi, C. Mansfield, C. Marijon, A. G. Guex, F. Perbellini, I. Bardi, E. J. Humphrey, J. L. Puetzer, D. Mawad, D. C. Koutsogeorgis, D. J. Stuckey, C. M. Terracciano, S. E. Harding, M. M. Stevens#. Auxetic cardiac partches with tunable mechanical and conductive properties toward treating myocardial infarction. Advanced Functional Materials. 2018, DOI: 10.1002/adfm.2018000618.

Menasché, P., Vanneaux, V., Hagège, A., Bel, A., Cholley, B., Parouchev, A., Cacciapuoti, I., Al-Daccak, R., Benhamouda, N., Blons, H. and Agbulut, O., 2018. Transplantation of Human Embryonic Stem Cell–Derived Cardiovascular Progenitors for Severe Ischemic Left Ventricular Dysfunction. Journal of the American College of Cardiology, 71(4), pp.429-438.

Mosqueira, D., Mannhardt, I., Bhagwan, J.R., Lis-Slimak, K., Katili, P., Scott, E., Hassan, M., Prondzynski, M., Harmer, S.C., Tinker, A. and Smith, J.G., 2018. CRISPR/Cas9 editing in hPSC-cardiomyocytes highlights arrhythmias, hypo-contractility and energy depletion as potential therapeutic targets for HCM. European Heart Journal.

Perbellini F, Watson SA, Scigliano M, Alayoubi S, Tkach S, Bardi I, Quaife N, Kane C, Dufton NP, Simon A, Sikkel MB, Faggian G, Randi AM, Gorelik J, Harding SE, Terracciano CM. Investigation of cardiac fibroblasts using myocardial slices. Cardiovasc Res. 2018 Jan 1;114(1):77-89

Richardson, G., Sage, A., Bennaceur, K., Al Zhrany, N., Coelho-Lima, J., Dookun, E., Draganova, L., Saretzki, G., Breault, D.T., Mallat, Z. and Spyridopoulos, I., 2018. Telomerase Mediates Lymphocyte Proliferation but Not the Atherosclerosis-Suppressive Potential of Regulatory T-Cells. Arteriosclerosis, thrombosis, and vascular biology, pp.ATVBAHA-117.

Watson SA, Scigliano M, Bardi I, Ascione R, Terracciano CM, Perbellini F. Preparation of viable adult ventricular myocardial slices from large and small mammals. Nat Protoc. 2017 Dec;12(12):2623-2639