Research Associate - Heart Science Section NHLI
Department / Division/Faculty
National Heart and Lung Institute / Cardiovascular Science / Medicine
Salary £36,800 - £44,220 per annum
The Heart Science section is focused on the molecular genetics of cardiac muscle growth, death and regeneration, building on insights from developmental and stem cell biology. Our research is directed towards understanding how the function of the constituent cells of the heart leads to the clinical manifestations of disease and how new treatments may be discovered and tested.
You will conduct and help design experiments in small-mammal models of myocardial infarction (permanent coronary artery occlusion, and ischemia-perfusion injury) to evaluate novel paracrine factors and their ability to reduce cardiac injury, via direct effects on cardiomyocytes or indirect effects via the inflammatory milieu. These experiments will entail factor delivery to the intact heart, using collagen patches (Wei, Nature 2015) or other biomaterials. You will perform in vivo microsurgical procedures in models of cardiac injury, with appropriate training and supervision. This is the primary responsibility of the post.
We are looking for a motivated researcher who has first-hand experience with murine models, and who would like to develop further skills in this area. You will have responsibility for transgenic colony maintenance and genotyping and will help co-ordinate a number of breeding and phenotyping studies. Experience of in vivo research techniques and holding of a Home Office license are highly desirable; training in in vivo cardiac phenotyping will be provided.
Committed to equality and valuing diversity. We are also an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Disability Confident Employer and are working in partnership with GIRES to promote respect for trans people.The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/
|23 October 2017 (midnight BST)|
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