Mechanical forces shape the form and function of biological systems and regulate biological processes across all levels and scales. The motion of joints, contraction of cells, and even the conformation of proteins are all governed by mechanical principles, which together define biological function in health and disease.
Investigators in the Department of Bioengineering seek to understand the pervasive role of mechanics in biology by combining the latest tools of engineering and the life sciences to answer the most pressing questions in health and disease.
With specific interests in cardiovascular, musculoskeletal, orthopaedic, ophthalmic, and respiratory systems, our investigators apply experimental, computational and theoretical approaches to understand how mechanical forces impact biological function at the molecular, cellular, tissue, organ and organism levels.
Academic staff in this area
- Hari Arora: Lung mechanics
- Anthony Bull: Musculoskeletal mechanics – sports, ageing and high speed impact.
- Etienne Burdet: Human neuromechanical control.
- Colin Caro: Haemodynamics and mass transport in vascular biology/pathology.
- Armando Del Rio Hernandez: Cellular and molecular mechanotransduction.
- James Choi: Tissue elasticity imaging, treatment of vascular diseases, and ultrasonic mechanotransduction.
- Angela Kedgley: Orthopaedic biomechanics of the upper limb.
- Andrei Kozlov: Auditory neuroscience and biophysics.
- Rob Krams: Mechanosensing and Atherosclerosis.
- Chiu Fan Lee: Collective motion in living organisms.
- Spyros Masouros: Injury biomechanics – high energy trauma and its protection.
- Charles Michel: Microvascular exchange and permeability.
- James Moore: Cardiovascular and Lymphatic Biomechanics and Device Development.
- Niamh Nowlan: Mechanobiology of prenatal skeletal development.
- Darryl Overby: Mechanics and mechanobiology of cells and tissues.
- Kim Parker: Physiological mechanics in the cardiovascular system.
- Bob Schroter: Flow and mass transport in the respiratory system.
- Mengxing Tang: Imaging and quantifying macro- and micro- flow and tissue mechanical properties using ultrasound.
- Jennifer Tweedy: Mathematical modelling, biofluid mechanics and biocontinuum mechanics.
- Peter Weinberg: Biomechanics of atherosclerosis, permeability and blood flow, assessment of endothelial function by analysis of the pulse waveform.