Systems Biology is an approach to understanding biological systems by integrating experimental data with mathematical and computational modelling. By their nature, systems biology project tend to be larger, cross-discipline activities. The BDSG has been involved with a number of projects in recent years.

Current projects

Mapping combinatorial stress responses in bacteria using chimeric proteins and probabilistic modelling

PI: Prof. Martin Buck

Funding body: BBSRC

Grant reference: BB/G020434/1

BDSG contact: Geraint Barton

Selected completed projects


The Centre for Integrative Systems Biology at Imperial College (CISBIC) was established following the award of £6m by the BBSRC and EPSRC to enable multi-disclipinary research combining theory, computer modelling and experiments in a systems approach across the life sciences.

The BDSG provided bioinformatics support to members of CISBIC, with two members of staff tasked with developing the data infrastructure for the centre.

CISBIC has now merged with the Centre for Bioinformatics, forming the Centre for Integrative Systems Biology and Bioinformatics (CISBIO).

Funding body: BBSRC/EPSRC

Grant reference: BB/C519670/1 

Website: CISBIC

BDSG Contact: Dr. Sarah Butcher

Infrastructure for Systems Biology Europe

Funding body: EU FP7

Grant reference: 312455

BDSG contact: Dr. Sarah Butcher