Next generation sequencing (NGS) software

Understanding the quality of your sequence is key to carrying out rigorous analysis

Aligning sequence reads against a reference is one of the first parts of many NGS processes

Genetic variation is responsible for many phenotypic differences between individuals and species

Assembly of genome and transcriptome without reference to existing sequence

Relative quantification of gene expression through mRNA sequencing

Identification of genomic loci enriched in aligned reads through i.e. ChIP-Seq transcription factor binding site assays

Imperial College London