BibTex format

author = {Parkes, M and Tallia, F and Young, G and Cann, P and Jones, J and Jeffers, J},
doi = {10.1016/j.msec.2020.111495},
journal = {Materials Science and Engineering C: Materials for Biological Applications},
pages = {1--10},
title = {Tribological evaluation of a novel hybrid for repair of articular cartilage defects},
url = {},
volume = {119},
year = {2021}

RIS format (EndNote, RefMan)

AB - The friction and wear properties of silica/poly(tetrahydrofuran)/poly(ε-caprolactone) (SiO2/PTHF/PCL-diCOOH) hybrid materials that are proposed as cartilage tissue engineering materials were investigated against living articular cartilage. A testing rig was designed to allow testing against fresh bovine cartilage. The friction force and wear were compared for five compositions of the hybrid biomaterial articulating against freshly harvested bovine cartilage in diluted bovine calf serum. Under a non-migrating contact, the friction force increased and hence shear force applied to the opposing articular cartilage also increased, resulting in minor damage to the cartilage surface. This worse case testing scenario was used to discriminate between material formulations and revealed the increase in friction and damaged area was lowest for the hybrid containing the most silica. Further friction and wear tests on one hybrid formulation with an elastic modulus closest to that of cartilage were then conducted in a custom incubator system. This demonstrated that over a five day period the friction force, cell viability and glucosaminoglycan (GAG) release into the lubricant were similar between a cartilage-cartilage interface and the hybrid-cartilage interface, supporting the use of these materials for cartilage repair. These results demonstrate how tribology testing can play a part in the development of new materials for chondral tissue engineering.
AU - Parkes,M
AU - Tallia,F
AU - Young,G
AU - Cann,P
AU - Jones,J
AU - Jeffers,J
DO - 10.1016/j.msec.2020.111495
EP - 10
PY - 2021///
SN - 0928-4931
SP - 1
TI - Tribological evaluation of a novel hybrid for repair of articular cartilage defects
T2 - Materials Science and Engineering C: Materials for Biological Applications
UR -
UR -
UR -
UR -
VL - 119
ER -