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    Villette C, Modenese L, Phillips ATM, 2014,

    Combined finite element and musculoskeletal predictive structural modelling of the femur: Potential mechanobiology applications

    Walker NM, Eardley W, Clasper JC, 2014,

    UK combat-related pelvic junctional vascular injuries 2008-2011: Implications for future intervention

    Wilgeroth JM, Nguyen T-TN, Proud WG, 2014,

    Interaction between blast wave and reticulated foam: assessing the potential for auditory protection systems

    , 18th Joint Int Conf of the APS Topical-Grp on Shock Compress of Condensed Matter / 24th Int Conf of the Int-Assoc-for-the-Advancement-of-High-Pressure-Sci-and-Technol, Publisher: IOP PUBLISHING LTD, ISSN: 1742-6588
    Gopalakrishnan A, Modenese L, Phillips ATM, 2013,

    Generating computer simulations of movement using muscle synergy inputs

    , International Society of Biomechanics
    Masouros SD, Brown KA, Clasper J, Proud WGet al., 2013,

    Briefing: Blast effects on biological systems

    , Proceedings of the Institution of Civil Engineers: Engineering and Computational Mechanics, Vol: 166, Pages: 113-118, ISSN: 1755-0777

    A signature of current conflicts is the use of buried improvised explosive devices to cause injury to military personnel and damage to their vehicles. Explosive devices also cause injuries to non-military populations in current and former conflict zones. The nature and placement of the explosive charge has a marked effect on the loading experienced. In all situations, damage to tissues occurs when the energy and loading rate exceeds that which the human body can support. Currently, it is difficult to predict the various time-dependent effects of blast injury because of the complexities of the rapid initial accelerations, the loading geometries and the heterogeneous nature of the tissues that can be damaged. An outline of the ways in which one may study how explosive energy interacts with biological systems is presented along with a discussion of how the data generated can be used to develop improved, costeffective strategies for studying blast injury processes.

    Masouros SD, Newell N, Ramasamy A, Bonner TJ, West ATH, Hill AM, Clasper JC, Bull AMJet al., 2013,

    Design of a Traumatic Injury Simulator for Assessing Lower Limb Response to High Loading Rates

    , ANNALS OF BIOMEDICAL ENGINEERING, Vol: 41, Pages: 1957-1967, ISSN: 0090-6964
    Modenese L, Gopalakrishnan A, Lloyd DG, Phillips ATMet al., 2013,

    Falsification of a lower limb model predicting hip contact force vectors

    , International Society of Biomechanics
    Modenese L, Gopalakrishnan A, Phillips ATM, 2013,

    Application of a falsification strategy to a musculoskeletal model of the lower limb and accuracy of the predicted hip contact force vector

    , JOURNAL OF BIOMECHANICS, Vol: 46, Pages: 1193-1200, ISSN: 0021-9290
    Newell N, Masouros SD, Bull AMJ, 2013,

    A comparison of MiL-Lx and hybrid-III responses in seated and standing postures with blast mats in simulated under-vehicle explosions

    , 2013 IRCOBI Conference Proceedings - International Research Council on the Biomechanics of Injury, Pages: 135-144

    Blast mats that can be retrofitted to the floor of military vehicles are considered to reduce the risk of injury from under-vehicle explosions. Anthropometric test devices (ATDs) are validated for use only in the seated position. The aim of this study was to use a traumatic injury simulator fitted with 3 different blast mats in order to assess the ability of 2 ATD designs to evaluate the protective capacity of the mats in 2 occupant postures under 2 severities. Tests were performed for each combination of mat design, ATD, severity and posture using an antivehicle under-belly injury simulator. The differences between mitigation systems were larger under the H-III compared to the MiL-Lx. There was little difference in how the 2 ATDs and how posture ranked the mitigation systems. Results from this study suggest that conclusions obtained by testing in the seated position can be extrapolated to the standing. However, the different percentage reductions observed in the 2 ATDs suggests different levels of protection. It is therefore unclear which ATD should be used to assess such mitigation systems. A correlation between cadavers and ATDs on the protection offered by blast mats is required in order to elucidate this issue.

    Prinold JAI, Villette CC, Bull AMJ, 2013,

    The influence of extreme speeds on scapula kinematics and the importance of controlling the plane of elevation

    , CLINICAL BIOMECHANICS, Vol: 28, Pages: 973-980, ISSN: 0268-0033
    Proud WG, 2013,

    The physical basis of explosion and blast injury processes

    , JOURNAL OF THE ROYAL ARMY MEDICAL CORPS, Vol: 159, Pages: 4-9, ISSN: 0035-8665
    Proud WG, 2013,

    Future Research Areas

    , PROPELLANTS EXPLOSIVES PYROTECHNICS, Vol: 38, Pages: 167-167, ISSN: 0721-3115
    Ramasamy A, Hill AM, Masouros S, Gibb I, Phillip R, Bull AMJ, Clasper JCet al., 2013,

    Outcomes of IED foot and ankle blast injuries.

    , J Bone Joint Surg Am, Vol: 95

    BACKGROUND: Improvements in protection and medical treatments have resulted in increasing numbers of modern-warfare casualties surviving with complex lower-extremity injuries. To our knowledge, there has been no prior analysis of foot and ankle blast injuries as a result of improvised explosive devices (IEDs). The aims of this study were to report the pattern of injury and determine which factors are associated with a poor clinical outcome. METHODS: U.K. service personnel who had sustained lower leg injuries following an under-vehicle explosion from January 2006 to December 2008 were identified with the use of a prospective trauma registry. Patient demographics, injury severity, the nature of the lower leg injury, and the type of clinical management were recorded. Clinical end points were determined by (1) the need for amputation and (2) ongoing clinical symptoms. RESULTS: Sixty-three U.K. service personnel (eighty-nine injured limbs) with lower leg injuries from an explosion were identified. Fifty-one percent of the casualties sustained multisegmental injuries to the foot and ankle. Twenty-six legs (29%) required amputation, with six of them amputated because of chronic pain eighteen months following injury. Regression analysis revealed that hindfoot injuries, open fractures, and vascular injuries were independent predictors of amputation. At the time of final follow-up, sixty-six (74%) of the injured limbs had persisting symptoms related to the injury, and only nine (14%) of the service members were fit to return to their preinjury duties. CONCLUSIONS: This study demonstrates that foot and ankle injuries from IEDs are associated with a high amputation rate and frequently with a poor clinical outcome. Although not life-threatening, they remain a source of long-term morbidity in an active population.

    Ramasamy MA, Hill AM, Phillip R, Gibb I, Bull AMJ, Clasper JCet al., 2013,

    FASS is a Better Predictor of Poor Outcome in Lower Limb Blast Injury Than AIS: Implications for Blast Research

    , JOURNAL OF ORTHOPAEDIC TRAUMA, Vol: 27, Pages: 49-55, ISSN: 0890-5339
    Singleton JAG, Gibb IE, Bull AMJ, Mahoney PF, Clasper JCet al., 2013,

    Primary blast lung injury prevalence and fatal injuries from explosions: Insights from postmortem computed tomographic analysis of 121 improvised explosive device fatalities

    , JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, Vol: 75, Pages: S269-S274, ISSN: 2163-0755
    Singleton JAG, Gibb IE, Hunt NCA, Bull AMJ, Clasper JCet al., 2013,

    Identifying future 'unexpected' survivors: a retrospective cohort study of fatal injury patterns in victims of improvised explosive devices

    , BMJ OPEN, Vol: 3, ISSN: 2044-6055
    Villette CC, Thibon A, Modenese L, Phillips ATMet al., 2013,

    Combined musculoskeletal and finite element modelling of the femur

    , International Society of Biomechanics

    In the 1870’s, Wolff formulated a ‘trajectory theory’ about trabecular bone architecture which can be succinctly written as follows: bone adapts its structure to loading conditions in a way that follows principal stress trajectories. In this study, it was assumed that the human femur is optimally adapted to the loading conditions experienced during daily activities such as walking or climbing stairs. Hence, an initially randomized structural mesoscale model of a femur was iteratively adapted to the loading conditions experienced during a range of daily activities. The resulting structure shows a good visual comparison with clinical observation and the model proved computationally efficient.

    Arora H, Hooper PA, Dear JP, 2012,

    Blast loading of sandwich structures and tubes

    , Dynamic Failure of Composite and Sandwich Structures, Editors: Abrate, Castanié, Rajapakse, ISBN: 9789400753297
    Arora H, Hooper PA, Del Linz P, Yang H, Chen S, Dear JPet al., 2012,

    Modelling the behaviour of composite sandwich structures when subject to air-blast loading

    , International Journal of Multiphysics, Vol: 6, Pages: 199-217, ISSN: 1750-9548

    Large-scale glass fibre reinforced polymer (GFRP) and carbon fibre reinforced polymer (CFRP) sandwich structures (1.6 m × 1.3 m) were subject to explosive air blast (100 kg TNT equivalent) at stand-off distances of 14 m. Digital image correlation (DIC) was used to obtain full-field data for the rear-face of each deforming target. A steel plate of comparable mass per unit area was also subjected to the same blast conditions for comparison. The experimental data was then verified with finite element models generated in Abaqus/Explicit. Close agreement was obtained between the numerical and experimental results, confirming that the CFRP panels had a superior blast performance to the GFRP panels. Moreover all composite targets sustained localised failures (that were more severe in the GFRP targets) but retained their original shape post blast. The rear-skins remained intact for each composite target with core shear failure present.

    Bo C, Balzer J, Hahnel M, Rankin SM, Brown KA, Proud WGet al., 2012,


    , 7th Biennial Conference of the American-Physical-Society-Topical-Group on Shock Compression of Condensed Matter, Publisher: AMER INST PHYSICS, ISSN: 0094-243X

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