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Engineering biological and biomedical systems to improve the human condition and the world around us

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Theme overview and objectives

Our aim is to achieve fundamental understanding of complex biological systems with the objective of improving human health, and making novel products using an industrial biotechnology approach. 

Methods and capabilities

Our biomedical engineering research focuses on the use of imaging techniques and the development of computational tools to achieve deep understanding of fluid flow behaviour in biological systems. Our protein-based biotechnology expertise ranges from protein production and purification, to stabilisation, while our cellular-based capabilities include proteomics, cell and gene therapies, and multi-scale modelling of biological systems; the latter encompasses cellular functions, tissue behaviour, biological transport, and drug delivery. We also have extensive expertise in bioprocess modelling, post-translational protein modification, and biomaterials.

Highlights

SyMBioSys logo
SyMBioSys is an H2020-sponsored MARIE SKLODOWSKA-CURIE Innovative Training Network (ITN) comprising of 11 academic and industrial partners. The main objective of SyMBioSys is to provide a new generation of innovative and entrepreneurial early-stage researchers (ESRs) that will develop cutting-edge kinetic models for biological processes via systems engineering research and will exploit these for designing novel biotechnological applications. Find out more

Fourier Transform Infrared (FTIR) spectroscopic imaging
We examine new non-destructive cell imaging techniques using Fourier Transform Infrared (FTIR) spectroscopic imaging. Find out more or read the paper in Chemical Society Reviews Attenuated total reflection Fourier-transform infrared (ATR-FTIR) imaging of tissues and live cells.

Highlight videos

Ultrafast desorption of colloidal particles

Researchers demonstrated how ultrasonic sound waves can be used to eject a coating of particles from a microscopic bubble's surface. The research findings have implications for targeted drug delivery. Read the paper in PNAS

Ultrafast desorption of colloidal particles

Ultrafast desorption of colloidal particles

Ultrafast desorption of colloidal particles from fluid interfaces

Researchers demonstrated how ultrasonic sound waves can be used to eject a coating of particles from a microscopic bubble's surface. The research findings have implications for targeted drug delivery. Read the paper in PNAS

Modelling Antibodies - Cleo Kontoravdi

Modelling Antibodies - Cleo Kontoravdi

A short video for the Watson Forum, a series of interviews that highlight contributions to modelling

The Watson Forum is a series of (informal) interviews that seek to highlight contributions of women in the areas of numerical modelling, simulation, and programming in the context of Maths, Physics, Earth Sciences and Engineering.

The Watson Forum is aimed at motivating young ladies to embark in numerical and modelling topics, and to project ‘real’ female modelling role models to the world! Many of the interviewees have hybrid careers that combine modelling with other activities, such as experimental and field work. 

In the context of the Watson Forum, modelling is any activity that pertains to building any type of models (mathematical, geometric, computational, numerical, geological) to understand natural or manmade processes. This may include quantification, interpretation, prediction, simulation, visualisation, imitation, inspection, simplification, and many other activities related to understanding the world around us.

By highlighting the work of women in the simulation arena (in both industry and academia) we hope to increase the impact of their work, while encouraging others to pursue such careers.

Created by Adriana Paluszny, Imperial College London