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Issue 120, 5 July 2002
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Taking action on fatal lung disease
A two-year London project, Part of this weeks national Breathe
Easy Week organized by the British Lung Foundation, could
significantly improve understanding of Cystic
Fibrosis and help reduce unnecessary deaths. Action Research the medical charity celebrating its fiftieth
anniversary this year, has agreed to fund almost £90,000
towards a new study focusing on a common but dangerous cause of
chronic lung infections. The offending bacterium or bug can be
difficult to overcome and is sometimes fatal, especially among
people with the inherited disease. Dr Tom Evans, a Consultant in Infectious Diseases at the
Imperial College Londons Hammersmith campus, is leading the
research. Cystic Fibrosis is a chronic debilitating disease
which still leads to premature death of those affected, he
explained. Although life expectancy is improving, many people will
die in their teens and early twenties. Patients and families of those with Cystic
Fibrosis suffer enormously and anything that can be done to
help understand this common disease better is extremely
important. The study focuses on the bacterium, Pseudomonas
aeruginosa, known as Pa - the most common cause of
such lung infections which affects more than 80% of people with
Cystic Fibrosis. Remarkably difficult to eradicate, it is also increasingly
resistant to antibiotics. Lung infections caused by Pa are
also problematic to treat among people with compromised immune
systems, causing fatalities in more than half of affected Patients
on intensive care units. Found widely in natural and domestic environments, including
soil and plants, as many as 50,000 people suffer from Pa
at any one time in the UK. Typical symptoms include shortness of
breath, a phlegm-like cough, fever, and sometimes wheezing. |
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| ©2003 Imperial College London |
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