On Tuesday 14th July 4 pm, the Department of Surgery and Cancer and CRUK Imperial Centre will host a Webinar featuring talks on infrastructure at Imperial to help Cancer researchers with their translational projects.
This event will include presentations from:
1. Georgios Nteliopoulos – The Circulating Biomarker Laboratory
2. Kelly Gleason – How can Public and Patient engagement help with your research?
3. Mark Gurden – The CRUK Imperial Centre: facilitating cancer research at Imperial
There will be an opportunity to ask questions following the presentations.
ATTENDANCE
This webinar series is taking place via Teams. Cancer researchers from all departments and faculties at Imperial College London are welcome to join. Please use the following link to join.
ABSTRACTS
Georgios Nteliopoulos, Research Associate in the Circulating Biomarker Laboratory Facility
The Circulating Biomarker Laboratory is focused on the analysis of liquid biopsies such as circulating tumour cells (CTCs) and cell-free circulating tumour DNA (ctDNA), heterogeneous tumour tissue biopsies or leukemic biomarkers. In this talk Georgious will present all the services/ technologies on offer through the facility:
1. CTC analysis: CellSearch® (for detection, enrichment and enumeration of CTCs) and DEPArray™ NxT (for precise identification, characterisation and isolation of single CTCs) system. In addition, he will discuss the pipeline for downstream genomic analysis
2. ctDNA analysis: downstream molecular analyses using Ion Chef/ Ion Torrent S5 systems (Thermo Fisher Scientific) and the Oncomine cfNA Research Assays or the BRC Genomics facility Illumina platforms
3. RainDrop digital droplet PCR (ddPCR) platform (Raindance / Bio-Rad) for ultra-sensitive detection.
4. DEPArray application for isolation and characterization of 100% pure tumour and stromal cells from Formalin-Fixed Paraffin-Embedded (FFPE) tissue specimens and the downstream genomic analysis of each cell population.
Kelly Gleason, CRUK Lead Nurse/Nurse Consultant
The Imperial Involvement Group for Cancer has supported a number of studies around liquid biopsies in breast cancer research. They have been involved in various stages of the research cycle by supporting funding proposals to CRUK, reviewing Patient Information Sheets for studies which collected blood samples for cell free DNA and CTC analysis, they have sat on Data Monitoring and Trial Management Committees, helped with research dissemination by reviewing lay summaries of results and attended several Imperial Science Café’s where scientists and clinicians have shared study findings.
Mark Gurden, Translational Research Manager in CRUK Imperial Centre
The CRUK Imperial Centre facilitates cancer research across the entire length of the research lifecycle, from guidance around study design, to specialised technology and resources access, helping with grant applications, to clinical trials support. This talk will give a brief overview of the centre may facilitate research for Cancer at Imperial.