Citation

BibTex format

@inproceedings{Koullapis:2017,
author = {Koullapis, P and Nicolaou, L and Kassinos, S},
pages = {942--945},
publisher = {CMBE},
title = {The effect of mouth-throat geometry on regional deposition in the tracheobronchial tree},
url = {http://www.compbiomed.net/2017/cmbe-proceedings.htm},
year = {2017}
}

RIS format (EndNote, RefMan)

TY  - CPAPER
AB - In silico methods offer a valuable approach to predict localized deposition in the tracheobronchialtree, important in the topical treatment of respiratory diseases and the systemic administration ofdrugs with limited lung bioavailability. In this study, we examine the effect of extrathoracic airwayvariation on regional deposition in order to assess whether standard mouth-throat models canbe adopted for more efficient predictions. Despite large qualitative differences in the extrathoracicairways, deposition patterns and efficiencies in the tracheobronchial region remain largely unaffectedfor particles smaller than 6 microns. The findings suggest that for drug delivery applications, standardmouth-throat models could be adopted to predict deposition in the central airways.
AU - Koullapis,P
AU - Nicolaou,L
AU - Kassinos,S
EP - 945
PB - CMBE
PY - 2017///
SN - 2227-3085
SP - 942
TI - The effect of mouth-throat geometry on regional deposition in the tracheobronchial tree
UR - http://www.compbiomed.net/2017/cmbe-proceedings.htm
UR - http://hdl.handle.net/10044/1/50627
ER -