Preprints:

"Theory of apparent circular dichroism in a magnetic field" Cameron, R. P.*; Wade, J.; Fuchter, M. J. Optica Open 2023DOI

 

Recent papers (2024):

"Chiral materials and mechanisms for circularly polarized light-emitting diodes" Furlan,  F.; Moreno-Naranjo, J. M.; Gasparini, N.; Feldmann, S.; Wade, J.; Fuchter M. J.* Nature Photon. 2024, asap. DOI

"Arylazobenzimidazoles: Versatile Visible-Light Photoswitches with Tuneable Z-isomer Stability" Steinmüller, S. A. M.; Odaybat, M.; Galli, G.; Prischich, D.; Fuchter, M. J.*; Decker, M.* Chem. Sci. 2024, asap. DOI

"Rational Design of New Conjugated Polymers with Main Chain Chirality for Efficient Optoelectronic Devices: Carbo[6]Helicene and Indacenodithiophene Copolymers as Model Compounds" Gedeon, C.; Del Rio, N.; Furlan, F.; Taddeucci, A.; Vanthuyne, N.; Gregoriou, V. G.; Fuchter, M. J.; Siligardi, G.; Gasparini, N.; Crassous, J.*; Chochos, C. L.* Adv. Mater. 2024, asap. DOI

"Helitwistacenes Combining Lateral and Longitudinal Helicity Results in Solvent-Induced Inversion of Circularly Polarized Light" Shioukhi, I.; Batchu, H.; Schwartz, G.; Minion, L.; Deree, Y.; Bogoslavsky, B.; Shimon, L. J. W.; Wade, J.; Hoffman, R.; Fuchter, M. J.; Markovich, G.; Gidron, O.* Angew. Chem. Int. Ed. 2024, e202319318. DOI

"Incorporating Photoresponses into Porous Liquids" Brand, M. C.; Trowell, H. G.; Fuchter, M. J.; Greenaway, R. L.* Chem. Eur. J. 2024, e202303593. DOI

 

2023:

"Disequilibrating azoarenes by visible-light sensitization under confinement" Gemen, J.; Church, J. R.; Ruoko, T. -P.; Durandin, N.; Białek, M.;  Weißenfels, M.; Feller, M.; Kazes, M.; Odaybat, M.; Borin, V. A.; Kalepu, R.; Diskin-Posner, Y.; Oron, D.; Fuchter, M. J.; Priimagi, A.; Schapiro, I.*; Klajn, R.*  Science, 2023, 381, 1357. DOI 

"The conducting state of TRPA1 modulates channel lateral mobilitySampieri, A.; Padilla-Flores, T.; Thawani, A. R.; Lam, P. -Y.; Fuchter, M. J.; Petersen, Vaca, L.* Cell Calcium, 2023, 116, 102800DOI

"Epidrugs as Promising Tools to Eliminate Plasmodium falciparumArtemisinin-Resistant and Quiescent Parasites" Reyser, T.; Paloque, L.; Nguyen, M.; Augereau, J. M.; Fuchter, M. J.; Lopez, M.; Arimondo, P. B.; Hassell-Hart, S.; Spencer, J.; Di Stefano, L.; Benoit-Vical, F. Pharmaceutics 2023, 15, 2440. DOI - invited submission to Recent Advances in Drug Therapy for Malaria special issue

"Systematic Investigation into the Photoswitching and Thermal Properties of Arylazopyrazole-based MOF Host–Guest Complexes" Griffiths, K.; Greenfield, J. L.; Halcovitch, N. R.; Fuchter, M. J.; Griffin, J. M.* Cryst. Growth Des. 2023, 23, 7044DOI

"Insights into the origins of inverted circular dichroism in thin films of a chiral side chain polyfluorene" Minion, L.; Wade, J.; Moreno-Naranjo, J. M.; Ryan, S.; Siligardi, G.; Fuchter, M. J.* Chirality 2023, 35, 817. DOI - invited submission to Chiral Materials special issue

"The CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer" Constantin, T. A.; Varela-Carver, A.; Greenland, K. K.; de Almeida, G. S.; Olden, E.; Penfold, L.; Ang, S.; Ormrod, A.; Leach, D. A.; Lai, C. -F.; Ainscow, E. K.; Bahl, A. K.; Carling, D.; Fuchter, M. J.; Ali, S.; Bevan, C. L.* Br. J. Cancer 2023, 128, 2326. DOI

"Dual inhibition of EZH2 and G9A/ GLP histone methyltransferases by HKMTI-1-005 promotes differentiation of acute myeloid leukemia cells" Sbirkov, Y.; Schenk, T.; Kwok, C.; Stengel, S.; Brown, R.; Brown, G.; Chesler, L.; Zelent, A.; Fuchter, M. J.; Petrie, K. Front. Cell Dev. Biol. 2023, 11, 1076458. DOI

"Enantiomerically Pure Fullerenes as a Means to Enhance the Performance of Perovskite Solar Cells" Shi, W.; Zhuang, Q.; Zhou, R.; Hou, X.; Zhao, X.*; Kong J.*; Fuchter, M. J.* Adv. Energy Mater. 2023, 13, 2300054. DOI

"Materials for chiral light control" Crassous, J.; Fuchter, M. J.; Freedman, D. E.; Kotov, N. A.; Moon, J.; Beard, M. C.; Feldmann, S. Nature Rev. Mater. 2023, 8, 365. DOI

"Anomalous circularly polarized light emission in organic light-emitting diodes caused by orbital–momentum locking" Wan, L*.; Liu, Y.; Fuchter, M. J.; Yan, B.* Nature Photon. 2023, 17, 193. DOI

"Plasmodium falciparum protein Pfs16 is a target for transmission-blocking antimalarial drug development" Yahiya, S.; Saunders, C. N.; Hassan, S.; Straschil, U.; Fischer, O. J.; Rueda-Zubiaurre, A.; Haase, S.; Vizcay-Barrena, G.; Famodimu, M. T.; Jordan, S.; Delves, M. J.; Tate, E. W.; Barnard, A.; Fuchter, M. J.; Baum, J.* Dis. Model Mech. 2023, 16, dmm049950. DOI

 

2022:

"MASC 2022: What challenges and opportunities do supramolecular chemists face in coming years?" (Voices article) Pilgrim, B. S.; Slater, A.; Collins, B.; Hiscock, J.; Leigh, J.; Sessler, J.; Peluso, L. L.; Fuchter, M. J.; Friščić, T.; Ashbridge, Z. Cell Rep. Phys. Sci. 2022, 3, 101199. DOI

"Data-driven discovery of molecular photoswitches with multioutput Gaussian processes"  Griffiths, R. R.; Greenfield, J. L.; Thawani, A. R.; Jamasb, A. R.; Moss, H. B.; Bourached, A.; Jones, P.; McCorkindale, W.; Aldrick, A. A.; Fuchter, M. J.; Lee, A. A.* Chem. Sci. 202213, 13541. DOI

"Controlling anisotropic properties through manipulation of chiral small molecule orientation" Wade, J.*; Salerno, F.; Kilbride, R. C.; Kim, D. K.; Schmidt, J. A.; Smith, J. A.; LeBlanc, L. M.; Wolpert, E.; Adeleke, A. A.; Johnson, E. R.; Nelson, J.; Mori, T.; Jelfs, K.; Heutz, S.; Fuchter, M. J.* Nature Chem. 202214, 1383. DOI  – highlighted on Chemistry World news

"Light Responsiveness and Assembly of Arylazopyrazole-Based Surfactants in Neat and Mixed CTAB Micelles" Tyagi, G.; Greenfield, J. L.; Jones, B. E.; Sharratt, W. N.; Khan, K.; Seddon, D.; Malone, L. A.; Cowieson, N.; Evans, R. C.; Fuchter, M. J.*; Cabral, J. T.* JACS Au 20222, 2670. DOI

"[5]-Helistatins: Tubulin-Binding Helicenes with Antimitotic Activity" Rushworth, J. R.; Thawani, A. R.; Fajardo-Ruiz, E.; Meiring, J. C. M.; Heise, C.; White, A. J. P.; Akhmanova, A.; Brandt, J. R.; Thorn-Seshold, O.; Fuchter, M. J.* JACS Au 2022, 2, 2561. DOI

"Photocontrolled Energy Storage in Azobispyrazoles with Exceptionally Large Light Penetration Depths" Gonzalez, A.; Odaybat, M.; Le, M.; Greenfield, J. L.; White, A. J. P.; Li, X.; Fuchter, M. J.*; Han, G. G. D. J. Am. Chem. Soc. 2022, 144, 19430. DOI

"Tuning Halide Composition Allows Low Dark Current Perovskite Photodetectors With High Specific Detectivity" Furlan, F.; Nodari, D.; Palladino, E.; Angela, E.; Mohan, L.; Briscoe, J.; Fuchter, M. J.; Macdonald, T. J.; Grancini, G.; McLachlan, M. A.; Gasparini, N.* Adv. Optical Mater. 202210, 2201816. DOI

"Emerging properties from mechanical tethering within a post-synthetically functionalised catenane scaffold" Hoyas Pérez, N.; Sherin, P. S.; Posligua, V.; Greenfield, J. L.; Fuchter, M. J.; Jelfs, K. E.; Kuimova, M. K.; Lewis, J. E. M.* Chem. Sci. 2022, 13, 11368. DOI

"Light-Mediated Multi-Target Protein Degradation using Arylazopyrazole Photoswitchable PROTACs (AP-PROTACs)" Zhang, Q.; Kounde, C. S.; Mondal, M.; Greenfield, J. L.; Baker, J. R.; Kotelnikov, S.; Ignatov, M.; Tinworth, C. P.; Zhang, L.; Conole, D.; De Vita, E.; Kozakov, D.; McCluskey, A.; Harling, J. D.; Fuchter, M. J.; Tate, E. W.* Chem. Commun. 2022, 58, 10933. DOI

"Best practices in the measurement of circularly polarised photodetectors" Ward, M. D.; Shi, W.;  Gasparini, N.; Nelson, J.; Wade, J.*; Fuchter, M. J.* J. Mater. Chem. C, 2022, 10, 10452. DOI

"Enhancing hole carrier injection via low electrochenmical doping of circularly polarized polymer light-emittting diodes" Yan, H.; Wade, J.; Wan, L.; Kwon, S.*; Fuchter, M. J.*; Campbell, A. J.; Kim, J. -S.* J. Mater. Chem. C, 202210, 9512. DOI

"Engineering the sign of circularly polarized emission in achiral polymer – chiral small molecule blends as a function of blend ratio" Wan, L.; Wade, J.; Wang, X.; Campbell, A. J.; Fuchter, M. J. * J. Mater. Chem. C. 2022, 10, 5168. DOI

"Dual G9A and EZH2 inhibition stimulates anti-tumour immune response in ovarian high-grade serous carcinoma" Spiliopoulou, P.; Spear, S.; Mirza, H.; Garner, I.; McGarry, L.; Grundland-Freile, F.; Cheng, Z.; Ennis, D. P.; Iyer, N.; McNamara, S.; Natoli, M.; Mason, S.; Blyth, K.; Adams, P.; Roxburgh, P.; Fuchter, M. J.; Brown, R. B.; McNeish, I. A.* Mol. Cancer. Ther. 2022, 21, 522. DOI

"High Responsivity Circular Polarized Light Detectors based on Quasi Two-Dimensional Chiral Perovskite FilmsLiu, T.; Shi, W.; Tang, W.; Liu, Z.; Schroeder, B. C.; Fenwick, O.*; Fuchter, M. J.ACS Nano, 202216, 2682. DOI

"An S-Shaped Double Helicene Showing both Multi-Resonance Thermally Activated Delayed Fluorescence and Circularly Polarized Luminescence" Marques dos Santos, J.; Sun, D.; Moreno Naranjo, J. M.; Hall, D.; Zinna, F.; Ryan, S. T. J.; Shi, W.; Matulaitis, T.; Cordes, D. B.; Slawin, A. M. Z.; Beljonne, D.; Warriner, S. L.; Olivier, Y.*; Fuchter, M. J.*; Zysman-Colman, E.* J. Mater. Chem. C. 2022, 10, 4861. DOI

 

2021:

"Highly Selective High-Speed Circularly Polarized Photodiodes Based on π-Conjugated Polymers" Ward, M. D.; Wade, J.; Shi, X.; Nelson, J.; Campbell, A. J.; Fuchter, M. J.* Adv. Opt. Mater2021, 2101044. DOI – selected as an Editors' Choice article

"Efficient Electrocatalytic Switching of Azoheteroarenes in the Condensed Phases" Greenfield, J. L.; Gerkman, M. A.; Gibson, R. S. L.; Han, G. G. D.*; Fuchter, M. J.* J. Am. Chem. Soc. 2021143, 15250DOI

"On the factors influencing the chiroptical response of conjugated polymer thin films" Laidlaw, B.; Eng, J.; Wade, J.; Shi, X. S.; Salerno, F.; Fuchter, M. J.; Penfold, T. J.* Chem. Commun. 202157, 9914. DOI

"Computational Screening of Chiral Organic Semiconductors: Exploring Side-Group Functionalization and Assembly to Optimize Charge Transport" Schmidt, J. A.; Weatherby, J. A.; Sugden, I. J.; Santana-Bonilla, A.; Salerno, F.; Fuchter, M J.; Johnson, E. R.; Nelson, J.; Jelfs, K. E.* Cryst. Growth Des. 202121, 5036. DOI – selected as an ACS Editors' Choice article

"Strongly Circularly Polarized Crystalline and β-Phase Emission from Poly(9,9-dioctylfluorene)-Based Deep-Blue Light-Emitting Diodes" Wan, L.; Shi, X.; Wade, J.; Campbell, A. J.; Fuchter, M. J.* Adv. Opt. Mater. 2021, 2100066. DOI

"Pathways to increase the dissymmetry in the interaction of chiral light and chiral molecules" Greenfield, J. L.; Wade, J.; Brandt, J. R.; Shi, X.; Penfold, T. J.; Fuchter, M. J.* Chem. Sci. 202112, 8589. DOI

"Photochemical probe identification of a small-molecule inhibitor binding site in Hedgehog acyltransferase (HHAT)Lanyon-Hogg, T.*; Ritzefeld, M.; Zhang, L.; Pogranyi, B.; Mondal, M.; Andrei, S. A.; Sefer, L.; Johnston, C. D.; Coupland, C. E.; Greenfield, J. L.; Newington, J.; Fuchter, M. J.; Magee, A. I.; Siebold, C.; Tate, E. W.* Angew. Chem. Int. Ed. 202160, 13542. DOI

"The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957Miguel-Blanco, C.; Murithi, J. M.; Benavente, E. D.; Angrisano, F.; Sala, K. A.; van Schalkwyk, D. A.; Vanaerschot, M.; Schwach, F.; Fuchter, M. J.; Billker, O.; Sutherland, C. J.; Campino, S. G.; Clark, T. G.; Blagborough, A. M.; Fidock, D. A.; Herreros, E.; Gamo, F. J.; Baum, J.; Delves, M. J.* Sci. Rep202111, Article number: 1888. DOI

"Fullerene dissymmetrization as a means to achieve single enantiomer electron acceptors with maximized chiroptical responsiveness" Shi, W.; Salerno, F.; Ward, M. D.; Santana-Bonilla, A.; Wade, J.; Hou, X.; Liu, T.; Dennis, T. J. S.; Campbell, A. J.; Jelfs, K. E.; Fuchter, M. J.* Adv. Mater. 2021, 33, 2004115. DOI – selected for inclusion as a back cover image

"500‐fold amplification of small molecule circularly polarized luminescence through circularly polarized FRET" Wade, J.; Brandt, J. R.; Zinna, F.; Amsharov, K. Y.; Jux, N.; Andrews, D. L.; Reger, D.; Fuchter, M. J. Angew. Chem. Int. Ed. 2021, 60, 222. DOI – selected as a “hot” paper and highlighted on ChemistryViews.org

 

2020:

"Natural optical activity as the origin of the large chiroptical properties in π-conjugated polymer thin films" Wade, J.; Hilfiker, J. N.; Brandt, J. R.; Liirò-Pelusoe, L.; Wan, L.; Shi, X.; Salerno, F.; Ryan, S. T. J.; Schöche, S.; Arteaga, O.; Jávorfi, T.; Siligardi, G.; Wang, C.; Amabilino, D. B.; Beton, P. H.; Campbell, A. J.*; Fuchter, M. J.* Nature Comms. 2020, 11, Article number: 6137. DOI – see accompanying behind the paper post, highlighted in Chemistry World.

"TRPswitch — a step function chemo-optogenetic ligand for the vertebrate TRPA1 channel" Lam, P. –Y.; Thawani, A. R.; Balderas, E.; White, A. J. P.; Chaudhuri, D.; Fuchter, M. J.; Peterson, R.* J. Am. Chem. Soc. 2020142, 17457. DOI

"Highly efficient inverted circularly polarized organic light emitting diodes" Wan, L.; Wade, J.; Shi, X.; Xu, S.Fuchter, M. J.*; Campbell, A. J.* ACS Appl. Mater. Interfaces 202012, 39471. DOI

"Glycosylated nanoparticles derived from RAFT polymerization for effective drug delivery to macrophages" Rushworth, J.; Montgomery, K.; Cao, B.; Brown, R.; Dibb, N.; Nilsson, S. K.; Chiefari, J.; Fuchter, M. J.* ACS Appl. Bio Mater. 20203, 5775. DOI

"The transcriptional repressor REV-ERB as a novel target for disease" Uriz-Huarte, A.; Date, A.; Ang, H.; Ali, S.; Brady, H. J. M.; Fuchter, M. J.* Bioorg. Med. Chem. Lett. 2020, 30, 127395. DOI

"On the promise of photopharmacology using photoswitches: a medicinal chemist’s perspective" Fuchter, M. J.* J. Med. Chem. 2020, 63, 11436. DOI

"Arylazopyrazoles for Long-Term Thermal Energy Storage and Optically Triggered Heat Release below 0 °C"  Gerkman, M. A.; Gibson, R. S. L.; Calbo, J.; Shi, Y.; Fuchter, M. J.*; Han, G. G. D.* J. Am. Chem. Soc. 2020, 142, 8688. DOI – Highlighted as a JACS Spotlight and in C&EN news

"UV‐Sensitive Wearable Devices for Colorimetric Monitoring of UV Exposure" Kurz, W.; Yetisen, A. K.*; Kaito, M. V.; Fuchter, M. J.; Jakobi, M.; Elsner, M.; Koch, A. W. Adv. Optical Mater. 2020, 1901969DOI

"Structure-activity relationship studies of a novel class of transmission blocking antimalarials targeting male gametes  Rueda-Zubiaurre, A.; Yahiya, S.; Fischer, O.; Hu, X.; Saunders, C.; Sharma, S.; Straschil, U.; Shen, J.; Tate, E. W.; Delves, M.; Baum, J.*; Barnard, A.*; Fuchter, M. J.* J. Med. Chem. 2020, 63, 2240. DOI – included in the Women in Medicinal Chemistry special issue

 

2019:

"A combinatorial approach to improving the performance of azoarene photoswitches" Calbo, J.; Thawani, A. R.; Gibson, R. S. L.; White, A. J. P. Fuchter, M. J.* Beilstein J. Org. Chem. 2019, 15, 2753DOI – included in the Molecular Switches special issue

"Inverting the Handedness of Circularly Polarized Luminescence from Light Emitting Polymers Using Film Thickness"  Wan, L;, Wade, J.; Salerno, F.; Arteaga, O.; Laidlaw, B.; Wang, X.; Penfold, T.; Fuchter, M. J. *; Campbell, A. J. * ACS Nano 2019, 13, 8099DOI

"Synthetic studies on the reverse antibiotic natural products, the nybomycins"  Bardell-Cox, O. A.;  White, A. J. P.; Aragón, L.*; Fuchter, M. J.* MedChemComm. 2019, 10, 1438. DOI - Invited Submission – Antimicrobial Resistance special issue

"Enantioselective reduction of N-alkyl ketimines with frustrated Lewis pair catalysis using chiral borenium ions" Mercea, D. M.; Howlett, M. G.; Piascik, A. D.; Scott, D. J.; Steven, A.; Ashley, A. E.; Fuchter, M. J.* Chem. Commun. 2019, 55, 7077DOI

"Chemical ZE isomer switching of arylazopyrazoles using acid" Gibson, R. S. L.; Calbo, J.; Fuchter, M. J.* ChemPhotoChem. 2019, 3, 372DOI - Invited Submission - Photoresponsive Molecular Switches and Machines special issue. Top 10% of downloaded papers in the period January 2018 – December 2019

"The influence of nitrogen position on charge carrier mobility in enantiopure aza[6]helicene crystals" Salerno, F.; Rice, B.; Schmidt, J. A.; Fuchter, M. J.; Nelson, J.; Jelfs, K. E.* Phys. Chem. Chem. Phys. 2019, 21, 5059DOI

"The antimalarial screening landscape—looking beyond the asexual blood stage"  Yahiya, S.; Rueda-Zubiaurre, A.; Delves, M. J.; Fuchter, M. J. Baum, J.* Curr. Opin. Chem. Biol. 2019, 50, 1DOI

Paper Archive:

2017-2018

2018

"A High Throughput Screen for Next-Generation Leads Targeting Malaria Parasite Transmission"   Delves, M.; Miguel-Blanco, C.; Matthews, H.; Molina, I.; Ruecker, A.; Yahiya, S.; Straschil, U.; Abraham, M.; Leon, M.-L.; Fischer, O.; Zubiaurre, A.; Brandt, J. R.; Cortes, A; Barnard, A.; Fuchter, M. J.; Calderon, F.; Winzeler, E.; Sinden, R.; Herreros, E.; Gamo, F.; Baum, J.* Nature Comm. 2018, 9, Article number: 3805. DOI (Highlighted at Eurekalert and other news sites)

"Unbiased Mass Spectrometry Elucidation of the Targets and Mechanisms of Activity-Based Probes: A Case Study involving Sulfonyl Fluorides"   Chavas, T. E. J.; Fuchter, M. J.; DiMaggio, P. A.* ACS Chem. Biol. 2018, 13, 2897DOI

Editorial for the 2018 Tetrahedron Young Investigator Award in Bioorganic and Medicinal Chemistry special issue Fuchter M. J.* Bioorg. Med. Chem. 2018, 26, 2919. DOI

"ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment" Patel, H.; Periyasamy, M.; Sava, G. P.; Bondke, A.; Slafer, B. W.; Kroll, S. H. B.; Barbazanges, M.; Starkey, R.; Ottaviani, S.; Harrod, A.; Aboagye, E. O.; Buluwela, L.; Fuchter, M. J.; Barrett, A. G. M.; Coombes, R. C.; Ali, S.* Mol. Cancer Ther. 2018, 17, 1156. DOI

"Development of a Photo-crosslinkable Diaminoquinazoline Inhibitor for Target Identification in Plasmodium falciparumLubin, A. S.; Zubiaurre, A. R.; Matthews, H.; Baumann, H.; Fisher, F. R.; Morales-Sanfrutos, J.; Hadavizadeh, K. S.; Nardella, F.; Tate, E. W.; Baum, J.; Scherf, A.; Fuchter, M. J.* ACS Infect. Dis. 2018, 4, 523. DOI - Invited Submission – Global Health special issue

"A computational exploration of the crystal energy and charge carrier mobility landscapes of the chiral [6]helicene molecule" Rice, B.; LeBlanc, L. M.; Otero-de-la-Roza, A.; Fuchter, M. J.; Johnson, E. R.; Nelson, J.; Jelfs, K. E.* Nanoscale 2018, 10, 1865. DOI

"Direct Reductive Amination of Carbonyl Compounds Catalyzed by a Moisture Tolerant Tin(IV) Lewis Acid" Sapsford, J. S.; Scott, D. J.; Allcock, N. J.; Fuchter, M. J.; Tighe, C. J.; Ashley, A.* Adv. Synth. Catal. 2018, 360, 1066. DOI

"Effective macrophage delivery using RAFT copolymer derived nanoparticles" Montgomery, K. S.; Davidson, R. W. M.; Cao, B.; Williams, B.; Simpson, G. W.; Nilsson, S. K.; Chiefari, J.; Fuchter, M. J.* Polym. Chem. 20189, 131. DOI


2017

"Intense Redox-Driven Chiroptical Switching with a 580 mV Hysteresis Actuated Through Reversible Dimerization of an Azoniahelicene" Brandt, J. R.; Pospíšil, L.; Bednárová, L.; Correa da Costa, R.; White, A. J. P.; Mori, T.; Teplý, F.; Fuchter, M. J.* Chem.Commun. 201753, 9059. DOI - inside cover article

"Emergent Properties of an Organic Semiconductor Driven by its Molecular Chirality" Yang, Y.; Rice, B.; Shi, X.; Brandt, J. R.; Correa da Costa, R.; Hedley, G. J.; Smilgies, D. –M.; Frost, J. M.; Samuel, I. D. W.; Otero-de-la-Roza, A.; Johnson, E. R.; Jelfs, K. E.; Nelson, J.; Campbell, A. J.*; Fuchter, M. J.* ACS Nano 201711, 8329. DOI

"Designing effective ‘frustrated Lewis pair’ hydrogenation catalysts" Scott, D. J.*; Fuchter, M. J.; Ashley, A. E.* Chem. Soc. Rev2017, 46, 5689-5700. DOI

"The added value of small-molecule chirality in technological applications" Brandt, J. R.; Salerno, F.; Fuchter, M. J.* Nature Rev. Chem2017, 1, 0045. DOIAccess a view-only version here.

"Identification of diaminoquinazoline histone lysine methyltransferase structure activity relationships that allow for segregation of human G9a inhibition and anti-Plasmodium activity" Sundriyal, S.; Chen, P. B.; Lubin, A. S.; Lueg, G. A.; Li, F.; White, A. J. P.; Malmquist, N. A.; Vedadi, M.; Scherf, A.; Fuchter, M. J.* MedChemComm 20178, 1069. DOI

Access the recommendation on F1000Prime"Thienopyrimidinone based sirtuin-2 (SIRT2)–selective inhibitors bind in the ligand induced 'selectivity pocket'" Sundriyal, S.; Moniot, S.; Mahmud, Z.; Yao, S.; Di Fruscia, P.; Reynolds, C. R.; Dexter, D. T.; Sternberg, M. J. E.; Lam, E. W.-F.; Steegborn, C.; Fuchter, M. J.* J. Med. Chem. 201760, 1928. DOI 

"Inhibitor selectivity for CDK7 - a structural, thermodynamic and modelling study" Hazel, P.; Kroll, S. B. H.; Bondke, A.; Barbazanges, M.; Patel, H.; Fuchter, M. J.; Coombes, R. C.; Ali, S.; Barrett, A. G. M.; Freemont, P.* ChemMedChem. 201712, 372. DOI

"Tuning Azoheteroarene Photoswitch Performance through Heteroaryl Design" Calbo, J.; Weston, C. E.; White, A. J. P.; Rzepa, H.; Contreras-García, J.*; Fuchter, M. J.* J. Am. Chem. Soc. 2017139, 1261. DOI

"Towards photopharmacological antimicrobial chemotherapy using photoswitchable amidohydrolase inhibitors" Weston, C. E.; Kraemer, A.; Colin, F.; Yildiz, O.; Baud, M. G. J.; Meyer-Almes, F. –J.; Fuchter, M. J.* ACS Infect. Dis20173, 152. DOI

2015-2016

2016

"Versatile Catalytic Hydrogenation Using A Simple Tin(IV) Lewis Acid" Scott, D. J.; Phillips, N. A.; Sapsford, J. S.; Deacy, A. C.; Fuchter, M. J.; Ashley, A. E.* Angew. Chem. Int. Ed201655, 14738. DOI

“Direct NHC-Catalysed Redox Amidation Using CO2 for Traceless Masking of Amine Nucleophiles” Davidson, R. W. D.; Fuchter, M. J.* Chem. Commun2016,  52, 11638. DOI (Highlighted by ChemistryWorld)

"Circularly Polarized Phosphorescent Electroluminescence with a High Dissymmetry Factor from PHOLEDs Based on a Platinahelicene" Brandt, J. R.; Wang, X.; Yang, Y.; Campbell, A.; Fuchter, M. J.* J. Am. Chem. Soc20161389743. DOI

"Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites" Chen, P. B.; Ding, S.; Zanghì, G.; Foulard  V.; DiMaggio, P. A.; Fuchter, M. J.; Mecheri, S.; Mazier, D.; Scherf, A.; Malmquist, N. A.* Sci. Rep. 2016,  6, Article number: 21802. DOI

"Photoswitchable basicity through the use of azoheteroarenes" Weston, C.; Richardson, R.; Fuchter, M. J.* Chem. Commun. 2016,  52, 4521. DOI


2015

"Young Career Focus: Dr. Matthew J. Fuchter" Synthesis 2015,  47, A150. DOI

"A Facile Protocol for Water-Tolerant ‘Frustrated Lewis Pair’-Catalyzed Hydrogenation" Scott, D. J.; Simmons, T. R.; Lawrence, E. J.; Wildgoose, G. G.; Fuchter, M. J.; Ashley, A. E.* ACS Catal. 2015,  5, 5540. DOI

"Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells" Curry, E.; Green, I.; Chapman-Rothe, N.; Shamsaei, E.; Kandil, S.; Cherblanc, F. L.; Payne, L.; Bell, E.; Ganesh, T.; Srimongkolpithak, N.; Caron, J.; Li, Fengling; Uren, A. G.; Snyder, J. P.; Vedadi, M.; Fuchter, M. J.*; Brown, R.* Clin. Epigenetics 20157:84  DOI

"Dual Wavelength Asymmetric Photochemical Synthesis with Circularly Polarized Light" Richardson, R. D.; Baud, M. G. J.; Weston, C. E.; Rzepa, H. S.; Kuimova, M. K.*; Fuchter, M. J.* Chem. Sci. 20156, 3853. DOI

"Design, synthesis and initial characterisation of a radiolabelled [18F]pyrimidoindolone probe for detecting activated caspase-3/7" Udemba, A.; Smith, G.; Nguyen, Q. -D.; Kaliszczak, M.; Carroll, L. S.; Fortt, R.; Fuchter, M. J.; Aboagye, E. O.* Org. Biomol. Chem. 201513, 5418. DOI

"Chiroptical studies on brevianamide B: Vibrational and Electronic Circular Dichroism confronted" Bultinck, P.; Cherblanc, F. L.; Fuchter, M. J.*; Herrebout, W. A.; Lo, Y. –L.; Rzepa, H. S.*; Siligardi, G.; Weimar, M. J. Org. Chem. 201580, 3359. DOI

"Histone methyltransferase inhibitors: orally bioavailable, fast acting molecules with activity against different human malaria species" Malmquist, N. A.*; Sundriyal, S.; Caron, J.; Chen, P.; Witkowski, B.; Menard, D.; Suwanarusk, R.; Renia, L.; Nosten, F.; Jiménez-Díaz, M. B.; Angulo-Barturen, I.; Martínez, M. S.; Ferrer, S.; Sanz, L. M.; Gamo, F. J.; Wittlin, S.; Duffy, S.; Avery, V. M.; Ruecker, A.; Delves, M. J.; Sinden, R. E.; Fuchter, M. J.; Scherf, A.* Antimicrob. Agents Chemother. 201559, 950. DOI

"The Discovery of a Highly Selective 5,6,7,8- Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson’s Disease Model" Di Fruscia, P.; Zacharioudakis, E.; Liu, C.; Moniot, S.; Laohasinnarong, S.; Khongkow, M.; Harrison, I. F.; Koltsida, K.; Reynolds, C. R.; Schmidtkunz, K.; Jung, M.; Chapman, K. L.; Steegborn, C.; Dexter, D. T.; Sternberg, M. J. E.; Lam, E. W.-F.; Fuchter, M. J.* ChemMedChem 201510, 69. DOI

2013-2014

2014

"Non-Metal Catalysed Hydrogenation of Carbonyl Compounds" Scott, D. J.; Fuchter, M. J.; Ashley, A. E.* J. Am. Chem. Soc. 2014, 136, 15813DOI (Highlighted in Chemical and Engineering news DOI)

"Identification of 2,4-Diamino-6,7-dimethoxyquinoline derivatives as G9a Inhibitors" Srimongkolpithak, N.; Sundriyal, S.; Lu, F.; Vedadi, M.; Fuchter, M. J.* Med. Chem. Commun. 2014, 5, 1821DOI - Invited Submission - Epigenetics special issue, cover article

"Metal-Free Hydrogenation Catalyzed by an Air-Stable Borane: Use of Solvent as a Frustrated Lewis Base" Scott, D. J.; Fuchter, M. J.; Ashley, A. E.* Angew. Chem. Int. Ed 2014, 53, 10218. DOI (Angew. Hot paper)

"Arylazopyrazoles: Azoheteroarene photoswitches offering quantitative isomerization and long thermal half-lives" Weston, C. E.; Richardson, R. D.; Haycock, P. R.; White, A. J. P.; Fuchter, M. J.* J. Am. Chem. Soc. 2014, 136, 11878. DOI

"Calcium-mediated stereoselective reduction of α,β-epoxy ketones"  Forkel, N. V.; Henderson, D. A.; Fuchter, M. J.* Tetrahedron Lett. 2014, 55, 5511. DOI

"Development of Diaminoquinazoline Histone Lysine Methyltransferase Inhibitors as Potent Blood-Stage Antimalarial Compounds" Sundriyal, S.; Malmquist, N. A.; Caron, J.; Blundell, S.; Liu, F.; Chen, X.; Srimongkolpithak, N.; Jin, J.; Charman, S. A.; Scherf, A.; Fuchter, M. J.* ChemMedChem 2014, 9, 2360. DOI

"Kinetic method for the large-scale analysis of the binding mechanism of histone deacetylase inhibitors" Meyners,C.; Baud, M. G. J.; Fuchter, M. J.; Meyer-Almes, F. -J.* Anal. Biochem. 2014, 460, 39. DOI

"PROFILE: Early Excellence in Physical Organic Chemistry" Fuchter, M. J. J. Phys. Org. Chem. 201427, 545. DOI - Investigator highlight of M. J. Fuchter

"Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures" Dembélé, L.; Franetich, J. –F.; Lorthiois, A.; Gego, A.; Zeeman, A. M.; Kocken, C. H. M.; Le Grand, R.; Dereuddre-Bosquet, N.van Gemert, G. –J.; Sauerwein, R.; Vaillant, J. –C.; Hannoun, L.; Fuchter, M. J.; Diagana, T.; Malmquist, N. A.; Scherf, A.; Snounou, G.*; Mazier, D. Nature Med. 2014, 20, 307. DOI (Highlighted in Nature Medicine DOI)

"Gold(I) mediated rearrangement of [7]-helicene to give a benzo[cd]pyrenium cation embedded in a chiral framework" Berger, R. J. F.; Fuchter, M. J.*;
 Krossing, I.; Rzepa, H. S.; Schaefer, J.; Scherer, H. Chem. Commun. 2014, 50, 5251. DOI - Invited Submission - 2014 Emerging Investigators issue

"Thermodynamics of ligand binding to histone deacetylase like amidohydrolase from Bordetella/Alcaligenes" Meyners, C.; Baud, M. G. J.; Fuchter, M. J.; Meyer-Almes, F. -J.* J. Mol. Recognit. 2014, 27, 160. DOI


2013

"Mechanistic and chiroptical studies on the desulfurization of epidithiodioxopiperazines reveal universal retention of configuration at the bridgehead carbon atoms." Cherblanc, F. L.; Lo, Y. -P.; Herrebout, W.; Bultinck, P.; Rzepa, H. S.*; Fuchter, M. J.* J. Org. Chem. 2013, 78, 11646. DOI

"On the histone lysine methyltransferase activity of fungal metabolite chaetocin" Cherblanc, F. L.; Chapman, K.; Reid, J.; Borg, A.; Sundriyal, S.; Alcazar-Fuoli, L.; Bignell, E.; Demetriades, M.; Schofield, C. J.; Dimaggio, P.; Brown, R.; Fuchter, M. J.*J. Med. Chem. 2013, 56, 8616. DOI

"Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance." Kaliszczak, M.; Patel, H.; Kroll, S. H.; Carroll, L.; Smith, G.; Delaney, S.; Heathcote, D. A.; Bondke, A.; Fuchter, M. J.; Coombes, R. C.; Barrett, A. G. M.; Ali, S.; Aboagye, E. O.* Br. J. Cancer 2013, 109, 2356. DOI

"ortho-Substituted 1,8-Diarylnaphthalenes: Conformational Thermodynamics and Kinetics" Judge, D.; Haycock, P.; Richardson, R.; Fuchter, M. J.* Synlett 2013, 24, 2365. DOI - Invited Submission - 2013 Young Investigator Workshop EuCheMS

"Circularly polarized light detection by a chiral organic semiconductor transistor" Yang, Y.; Correa da Costa, R.; Fuchter, M. J.*; Campbell, A. J.* Nature Photon. 2013, 7, 634. DOI (Highlighted in a College press release and associated video)

"Induction of Circularly Polarized Electroluminescence from an Achiral Light Emitting Polymer via a Chiral Small Molecule Dopant" Yang, Y.; Correa da Costa, R.; Smilgies, D. –M.; Campbell, A. J.*; Fuchter, M. J.* Adv. Mater. 2013, 25, 2624. DOI (Highlighted in a College press release and associated video)

"A Scalable and Expedient Route to 1-Aza[6]helicene Derivatives and Its Subsequent Application to a Chiral-Relay Asymmetric Strategy" Weimar, M.; Correa da Costa, R.; Lee, F. –H.; Fuchter, M. J.* Org. Lett. 2013, 15, 1706. DOI

"Stoichiometric C-H arylation of tricarbonyl(arene)-chromium complexes bearing pyridine directing groups" Fuchter, M. J.*; Judge, D. K.; Weimar, M.; White, A. J. P. Dalton Trans. 2013, 42, 5615. DOI

"Perspectives on Natural Product Epigenetic Modulators in Chemical Biology and Medicine" Cherblanc, F. ; Davidson, R.; Di Fruscia, P.; Srimongkolpithak, N.; Fuchter, M. J.* Nat. Prod. Rep. 2013, 30, 605.DOI - cover article (Amongst the top ten accessed articles from the online version of Natural Product Reports during the 2nd quarter of 2013 {April - June})

"Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases" Cherblanc, F.; Chapman, K. L.; Brown, R,; Fuchter, M. J.* Nature Chem. Biol. 2013, 9, 136. DOI

"Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors" Baud, M. G. J.; Leiser, T.; Petrucci, V.; Gunaratnam, M.; Neidle, S.; Meyer-Almes, F. -J.; Fuchter, M. J.* Beilstein J. Org. Chem. 2013, 9, 81. DOI - Invited Submission - Synthetic probes for the study of biological function themed issue

"Highly Ligand Efficient and Selective N-2-(Thioethyl)picolinamide Histone Deacetylase Inhibitors Inspired by the Natural Product Psammaplin A" Baud, M. G. J.; Haus, P.; Leiser, T.; Meyer-Almes, F. -J.; Fuchter, M. J.* ChemMedChem, 2013, 8, 149. DOI

"Synthesis of sterically encumbered C10-arylated benzo[h]quinolines using ortho-substituted aryl boronic acids" Weimar, M.; Fuchter, M. J.* Org. Biomol. Chem.. 2013, 11, 31. DOI

2011-2012

2012

"Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum" Malmquist, N. A.; Moss, T. A.; Mecheri, S.; Scherf, A.*; Fuchter, M. J.* P. Natl. Acad. Sci. USA 2012, 109, 16708. DOI (Highlighted in Nature Reviews Microbiology DOI)

"Lanthanide replacement in organic synthesis: Luche-type reduction of α,β-unsaturated ketones in the presence of calcium triflate" Forkel, N. V.; Henderson, D. A.; Fuchter, M. J.* Green Chem. 2012, 14, 2129. DOI -cover article

"[7]-Helicene: a chiral molecular tweezer for silver(I) salts" Fuchter, M. J.*; Schaefer, J.; Judge, D. K.; Wardzinsk,i B.; Weimar, M.; Krossing, I. Dalton Trans. 2012, 41, 8238. DOI

"Current limitations and future opportunities for epigenetic therapies" Cherblanc, F.; Chapman-Rothe, N.; Brown, R.*; Fuchter, M. J. Future Med. Chem. 2012, 4, 425. DOI

"The Discovery of Novel 10,11-Dihydro-5H-dibenz[b,f]azepine SIRT2 Inhibitors" Di Fruscia, P.;Laohasinnarong, S.; Khongkow, M.; Ho, K.;K.; Kroll, S. B.; Islam, S. A.; Sternberg, M. J. E.; Schmidtkunz, K.; Jung, M.; Lam, E. W.-F.; Fuchter, M. J.* Med. Chem. Commun. 2012, 3, 373. DOI (Amongst the top ten accessed articles from the online version of MedChemComm in January 2012)

"Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A Against its Epigenetic Targets" Baud, M. G. J.; Leiser, T.; Haus, P.; Samlal, S.; Wong, A. C.; Wood, R. J.; Petrucci, V.;Gunaratnam, M.; Hughes, S. M.; Buluwela, L.; Turlais, F.; Neidle, S.; Meyer-Almes, F. J.; White, A. J. P.; Fuchter, M. J.* J. Med Chem. 2012, 55, 1731. DOI

"An Unusual Oxidative Rearrangement of [7]-Helicene" Fuchter, M. J.*; Weimar, M.; Yang, X.; Judge, D.K.; White, A. J. P. Tetrahedron Lett. 2012, 53,11 08 . DOI

"The Design and Synthesis of IBiox N-Heterocyclic Carbene Ligands Derived from Substituted Amino-Indanols" Levy, J. -N.; Latham, C.; Roisin, L.; Kandziora, N.; Di Fruscia, P.; White, A. J. P.; Woodward, S.; Fuchter, M. J.* Org. Biomol. Chem. 2012, 10, 512. DOI


2011

"On the Determination of the Stereochemistry of Semisynthetic Natural Product Analogues using Chiroptical Spectroscopy: Desulfurization of Epidithiodioxopiperazine Fungal Metabolites" Cherblanc, F.; Lo, Y.-P.; De Gussem, E.; Alcazar-Fuoli , L.; Bignell, E.; He, Y.; Chapman-Rothe, N.; Bultinck, P.; Herrebout, W. A.; Brown, R.; Rzepa H. S.; Fuchter, M. J.* Chem. Eur. J. 2011, 17, 11868. DOI

"On the Function of the Internal Cavity of Histone Deacetylase Protein 8: R37, a Crucial Residue for Catalytic Activity" Haider, S.; Joseph, C.; Neidle, S.; Fierke, C. A.; Fuchter, M. J.* Bioorg. Med. Chem. Lett. 2011, 2129. DOI

"New synthetic strategies towards Psammaplin A, access to natural product analogues" Baud, M. G. J.; Leiser, T.; Meyer-Almes, F. -J.; Fuchter, M. J.* Org. Biomol. Chem. 2011, 9, 659. DOI (Highlighted in an RSC blog)

Pre-2010

2010

"BS-194, a potent inhibitor of cyclin-dependent protein kinases 1, 2 and 9, demonstrates anti-tumor effects in human tumor xenografts following oral administration" Heathcote, D. A.; Patel, P.; Kroll, S. H. B.; Periyasamy, M.; Alikian, M.; Kanneganti, S.; Jogalekar, A. S.; Scheiper, B.; Brackow, J. Siwicka, A.; Fuchter, M. J.; Snyder, J. P.; Liotta, D. C.; Aboagye, E. O.; Coombes, R. C.; Barrett, A. G. M.; Ali, S.* J. Med Chem. 2010, 53, 8508. DOI

"N-Heterocyclic Carbene Mediated Activation of Tetravalent Silicon Compounds: A Critical Evaluation" Fuchter, M. J.* Chem. Eur. J. 2010, 16, 12286. DOI

"SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and -2" Peck, B.; Chen, C. –Y.; Ho K. K.; Di Fruscia, P.; Myatt, S. S.; Coombe s, R. C.; Fuchter, M. J.; Hsiao, C. –D.; Lam, E.* Mol. Cancer Ther. 2010, 9, 844. DOI (One of the most cited articles in Molecular Cancer Therapeutics in 2010)

"Isoxazolidine Martinelline analogs via intramolecular 1,3-Dipolar Cycloaddition Reactions of Nitrones" Saubern, S.*; Macdonald, J. M.; Ryan, J. H.; Woodgate, R. C. J.; Louie, T. S.; Fuchter, M. J.; Holmes, A. B. Tetrahedron 2010, 66, 2761. DOI


2009

"Push-Pull Tropylium-Fused Aminoporphyrazine" Ruggiero, A.; Fuchter, M. J.; Kokas, O. J.; Negru, M.; White, A. J. P.; Haycock, P. R.; Clays, K.; Hoffman, B. M.; Barrett, A. G. M.* Tetrahedron, 2009, 65, 9690. DOI

"Serendipitous Synthesis of Trimetallic Porphyrazine Triads" Goslinski, T.; Zhong, C.; Fuchter, M. J.; White, A. J. P.; Barrett, A. G. M.*; Hoffman, B. M.* Tetrahedron Lett. 2009, 50, 5178. DOI

"The development of a highly selective inhibitor of cyclin-dependent kinase 7 (CDK7) which demonstrates anti-tumor activity" Ali, S.*; Heathcote, D. A.; Kroll, S. H. B.; Jogalekar, A. S.; Scheiper, B.; Patel, H.; Brackow, J.; Siwicka, A. Fuchter, M. J. Periyasamy, M.; Tolhurst, R. S.; Kanneganti, S. K.; Snyder, J. P.; Liotta, D. C.; Aboagye, E. O.; Barrett, A. G. M.; Coombes, R. C. Cancer Res. 2009, 69, 6208. DOI


2008

Commentary: "Constrained Analogues of Procaine as Novel Small Molecule Inhibitors of DNA Methyltransferase-I" Fuchter, M. J.* Chemtracts: Org. Chem. 2008, 21, 161.

"One-Pot Formation of Allylic Chlorides from Carbonyl Derivatives" Fuchter, M. J.*; Levy, J. N. Org. Lett. 2008, 10, 4919. DOI

"Diaryl Ether Synthesis in Supercritical Carbon Dioxide in Batch and Continuous Flow Mode" Lee, J. –K.; Fuchter, M. J.; Williamson, R. M.; Leeke, G. A.; Bush, E. J.; McConvey, I. F.; Saubern, S.; Ryan, J. H.; Holmes, A. B.* Chem. Commun. 2008, 4780. DOI

"Clean, Efficient Synthesis of O-Silylcarbamates and Ureas in Supercritical Carbon Dioxide" Fuchter, M. J.; Smith, C. J.; Tsang, M. W. –S.; Boyer, A.; Saubern, S.; Ryan, J. H.; Holmes, A. B.* Chem. Commun.. 2008, 2152. DOI

"Porphyrazines: Designer Macrocycles via Peripheral Substituent Change" Fuchter, M. J.; Zhong, C.; Zong, H.; Hoffman, B. M.; Barrett, A. G. M.* Aust. J. Chem. 2008, 61, 235. DOI -Invited Research Front Review Submission


2007

"Multi-gram Synthesis of a Water Soluble Porphyrazine and derived seco-Porphyrazine Labeling Agents" Guinchard, X.; Fuchter, M. J.; Ruggiero, A.; Duckworth, B.; Barrett, A. G. M.*; Hoffman, B. M.* Org. Lett. 2007, 9, 5291. DOI


2006

"Porphyrazines as Molecular Scaffolds: Flexible Syntheses of Novel Multimetallic Complexes" Goslinski, T.; Zhong, C.; Fuchter, M. J.; White, A. J. P.; Barrett, A. G. M.*; Hoffman, B. M.* Inorg. Chem. 2006, 45, 3686. DOI

"ROMPsphere-Supported seco-Porphyrazines: Efficient and Recyclable Photo-Oxygenation Catalysts" Fuchter, M. J.; Hoffman, B. M.*; Barrett, A. G. M.* J. Org. Chem. 2006, 71, 724. DOI


2005

"ROM Polymerization-Capture-Release. Application to the Synthesis of Unsymmetrical Porphyrazinedithiols and Peripherally Metalated Derivatives" Fuchter, M. J.; Hoffman, B. M.*; Barrett, A. G. M.* J. Org. Chem. 2005, 70, 5086. DOI

"Synthesis of Porphyrazine-Octaamine, Hexamine and Diamine Derivatives" Fuchter, M. J.; Beall, L. S.; Baum, S. M.; Montalban, A. G.; Sakellariou, E. G.; Mani, N. S.; Miller, T.; White, A. J. P.; Williams, D. J.; Barrett, A. G. M.*; Hoffman, B. M.* Tetrahedro n, 2005, 61, 6115 . DO I

"ROM Polymerization-Capture-Release Strategy for the Chromatography-Free Synthesis of Novel Unsymmetrical Porphyrazines" Fuchter, M. J.; Vesper, B. J.; Murphy, K. A.; Collins, H. A.; Phillips, D.; Hoffman, B. M.*; Barrett, A. G. M.* J. Org. Chem. 2005, 70, 2793. DOI


2003

"Regiochemical observations on the lithiation of 1,2,4-trichlorobenzene and reaction with DMF and oxamide electrophiles in THF" Burton, A. J.*; Cardwell, K. S.; Fuchter, M. J.; Lindvall, M. K.; Patel, R.; Packham, T. W.; Prodger, J. C.; Schilling, M. B.; Walker, M. D. Tetrahedron Letters, 2003, 44, 5653. DOI


Book Chapters:

Ryan, S. T. J.; Fuchter, M. J. Helicenes for Optoelectronic Applications and Devices. In Helicenes. Synthesis, Properties and Applications. Crassous, J.; Stará, I.; Stary, I. Ed.; Wiley-VCH, 2022; Chapter 15.

Greenfield, J. L.; Thawani, A. R.; Odaybat, M.; Gibson, R. S. L.; Jackson, T. B.; Fuchter, M. J.* Azoheteroarenes. In Molecular Photoswitches: Chemistry, Properties, and Applications. Zbigniew L. P. Ed.; Wiley-VCH, 2022; Chapter 5.

Weimar, M.; Fuchter, M. J. Reaction with Nonaromatic Halides, Sulfonates, or Related. In Science of Synthesis: Compounds In Cross Coupling and Heck-Type Reactions 3; Larhead, M. Ed.; Thieme, 2012; Chapter 3.1.1.1.4.58.

 Fuchter, M. J., Betti Reaction. In Name Reactions in Heterocyclic Chemistry II; Li, Jie J., Corey, E. J. Eds.; Wiley: New York, September 2011; pp 352 - 359.

Fuchter, M. J., Nazarov Cyclization. In Name Reactions for Carbocyclic Ring Formations; Li, Jie J., Corey, E. J. Eds.; Wiley: New York, September 2010; pp 122 - 146.

Fuchter, M. J., Simmons Smith Cyclopropanation. In Name Reactions for Carbocyclic Ring Formations; L i, Jie J., Corey, E. J. Eds.; Wiley: New York, September 2010; pp 24 - 44.

Fuchter, M. J., Heck Reaction. In Name Reactions for Homologations Part I; Li, Jie J., Corey, E. J. Eds.; Wiley: New York, March 2009; pp 2 - 32.

Fuchter, M. J., Kumada Cross-Coupling Reaction. In Name Reactions for Homologations Part I; Li, Jie J., Corey, E. J. Eds.; Wiley: New York, March 2009; pp 47 - 69.

Fuchter, M. J., Tsuji-Trost Reaction. In Name Reactions for Homologations Part I; Li, Jie J., Corey, E. J. Eds.; Wiley: New York, March 2009; pp 185 - 211.

Fuchter, M. J., Arndt-Eistert Homologation. In Name Reactions for Homologations Part I; Li, Jie J., Corey, E. J. Eds.; Wiley: New York, March 2009; pp 336 - 349.

Fuchter, M. J., Oppenauer Oxidation. In Name Reactions of Functional Group Transformations; Li, Jie. J., Corey, E. J., Eds.; Wiley: New York, July 2007; pp 265 - 273.

Fuchter, M. J., Chugaev elimination. In Name Reactions of Functional Group Transformations; Li, Jie . J., Corey, E. J., Eds.; Wiley: New York, July 2007; pp 334 - 342.

Fuchter, M. J., Cope elimination reaction. In Name Reactions of Functional Group Transformations; Li, Jie. J., Corey, E. J., Eds.; Wiley: New York, July 2007; pp 343 - 353.


Patents:

Synthesis of ethynylpyridine GCN2 inhibitors treating cancersWhitlock, G.; Fuchter, M. J. 2021, WO2021250399

“Arylazoheteroaryl compounds with alkanoate groups for use as long-term phase change thermal energy storage with improved crystallinity and liquid stability” Han, G. G. D.; Gerkman, M. A.; Fisher, R.; Fuchter, M. J.; Grossman, J. C. 2021, WO2021158638

“"TRPSWITCH" - a step function chemo-optogenetic ligand” Fuchter, M. J. ; Thawani, A. R.; Peterson, R. T.; Lam, P. Y. 2021, WO2021030165

“Methods for expanding natural killer cells for therapeutic use against cancer and other diseases” Fuchter, M. J. ; Huarte, A. U.; Brady, H. J. M. 2020, WO2020002911

“Natural killer cell expansion for therapeutic applications” Brady, H. J.M.; Fuchter, M. J.; 2018, WO2018178666

“Expansion of natural killer cells with REV-ERB-inhibiting compound for therapy” Brady, H. J.M.; Fuchter, M. J.; 2018, WO2018158587

“Preparation of pyrazolo[1,5-a]pyrimidine-5,7-diamine compounds as cyclin dependent kinase (CDK) inhibitors and their therapeutic use” Bondke, A.; Kroll, S.; Barrett, A. G. M.; Fuchter, M. J. ; Slafer, B.; Ali, S.; Coombes, R. C.; Snyder, J. 2015, WO2015124941

“Electroluminescent compositions” Yang, Y.; Campbell, A. J.; Fuchter, M. J. 2014, WO2014016611

“Preparation of quinazoline derivatives for use as histone lysine methyltransferase (HKMTase) EZH2 inhibitors” Brown, R.; Fuchter, M. J.; Chapman-Rothe, N.; Srimongkolpithak, N.; Caron, J.; Snyder, J.; Ganesh, T.; Liu, J.; Sun, A. 2013, WO2013140148 

“Processes for preparing 5,7-diamino pyrazolo[1,5-.alpha.]pyrimidine derivatives via regioselective aminations of dichloro(pyrazolo)pyrimidines with primary and secondary amines” Liotta, D. C.; Synder, J. P.; Jogalekar, A. S.; Barrett, A. G. M.; Fuchter, M. J.; Cook, M.; Kroll, S. H. B. 2010, WO2010068838