@article{Hirose:2015:10.1039/c5ob01744k,
author = {Hirose, H and Tamai, H and Gao, C and Imamuru, A and Ishida, H and Feizi, T and Kiso, M},
doi = {10.1039/c5ob01744k},
journal = {Organic and Biomolecular Chemistry},
pages = {11105--11117},
title = {Total syntheses of disulphated glycosphingolipid SB1a and the related monosulphated SM1a},
url = {http://dx.doi.org/10.1039/c5ob01744k},
volume = {13},
year = {2015}
}

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TY  - JOUR
AB  - Total syntheses of two natural sulphoglycolipids, disulphated glycosphingolipid SB1a and the structurally related monosulphated SM1a, are described. They have common glycan sequences and ceramide moieties and are associated with human epithelial carcinomas. The syntheses featured efficient glycan assembly and the glucosyl ceramide cassette as a versatile building block. The binding of the synthetic sulphoglycolipids by the carcinoma-specific monoclonal antibody AE3 was investigated using carbohydrate microarray technology.
AU  - Hirose,H
AU  - Tamai,H
AU  - Gao,C
AU  - Imamuru,A
AU  - Ishida,H
AU  - Feizi,T
AU  - Kiso,M
DO  - 10.1039/c5ob01744k
EP  - 11117
PY  - 2015///
SN  - 1472-7781
SP  - 11105
TI  - Total syntheses of disulphated glycosphingolipid SB1a and the related monosulphated SM1a
T2  - Organic and Biomolecular Chemistry
UR  - http://dx.doi.org/10.1039/c5ob01744k
UR  - http://hdl.handle.net/10044/1/56548
VL  - 13
ER  - 

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