The Centre has a long history of developing new techniques for medical imaging (particularly in magnetic resonance imaging), transforming them from a primarily diagnostic modality into an interventional and therapeutic platform. This is facilitated by the Centre's strong engineering background in practical imaging and image analysis platform development, as well as advances in minimal access and robotic assisted surgery. Hamlyn has a strong tradition in pursuing basic sciences and theoretical research, with a clear focus on clinical translation.

In response to the current paradigm shift and clinical demand in bringing cellular and molecular imaging modalities to an in vivo – in situ setting during surgical intervention, our recent research has also been focussed on novel biophotonics platforms that can be used for real-time tissue characterisation, functional assessment, and intraoperative guidance during minimally invasive surgery. This includes, for example, SMART confocal laser endomicroscopy, time-resolved fluorescence spectroscopy and flexible FLIM catheters.


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  • JOURNAL ARTICLE
    Feng Y, Guo Z, Dong Z, Zhou X-Y, Kwok K-W, Ernst S, Lee S-Let al., 2017,

    An efficient cardiac mapping strategy for radiofrequency catheter ablation with active learning

    , INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY, Vol: 12, Pages: 1199-1207, ISSN: 1861-6410
  • CONFERENCE PAPER
    Lee S-L, 2017,

    Examining the use of a novel dynamic endovascular simulator to facilitate intelligent localization and robotic technologies

    , Vascular-Societies Annual Scientific Meeting, Publisher: WILEY, Pages: 16-16, ISSN: 0007-1323
  • JOURNAL ARTICLE
    Vyas K, Hughes M, Leff DR, Yang G-Zet al., 2017,

    Methylene-blue aided rapid confocal laser endomicroscopy of breast cancer

    , JOURNAL OF BIOMEDICAL OPTICS, Vol: 22, ISSN: 1083-3668
  • JOURNAL ARTICLE
    Zhang L, Ye M, Giataganas P, Hughes M, Bradu A, Podoleanu A, Yang G-Zet al., 2017,

    From Macro to Micro Autonomous Multiscale Image Fusion for Robotic Surgery

    , IEEE ROBOTICS & AUTOMATION MAGAZINE, Vol: 24, Pages: 63-72, ISSN: 1070-9932
  • BOOK
    Balocco S, Zuluaga MA, Zahnd G, Lee SL, Demirci Set al., 2016,

    Computing and Visualization for Intravascular Imaging and Computer-Assisted Stenting

    , ISBN: 9780128110195

    © 2017 Elsevier Ltd. All rights reserved. Computing and Visualization for Intravascular Imaging and Computer-Assisted Stenting presents imaging, treatment, and computed assisted technological techniques for diagnostic and intraoperative vascular imaging and stenting. These techniques offer increasingly useful information on vascular anatomy and function, and are poised to have a dramatic impact on the diagnosis, analysis, modeling, and treatment of vascular diseases. After setting out the technical and clinical challenges of vascular imaging and stenting, the book gives a concise overview of the basics before presenting state-of-the-art methods for solving these challenges. Readers will learn about the main challenges in endovascular procedures, along with new applications of intravascular imaging and the latest advances in computer assisted stenting. Brings together scientific researchers, medical experts, and industry partners working in different anatomical regions Presents an introduction to the clinical workflow and current challenges in endovascular Interventions Provides a review of the state-of-the-art methodologies in endovascular imaging and their applications Poses outstanding questions and discusses future research.

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