A primary motivation of our research is the monitoring of physical, physiological, and biochemical parameters - in any environment and without activity restriction and behaviour modification - through using miniaturised, wireless Body Sensor Networks (BSN). Key research issues that are currently being addressed include novel sensor designs, ultra-low power microprocessor and wireless platforms, energy scavenging, biocompatibility, system integration and miniaturisation, processing-on-node technologies combined with novel ASIC design, autonomic sensor networks and light-weight communication protocols. Our research is aimed at addressing the future needs of life-long health, wellbeing and healthcare, particularly those related to demographic changes associated with an ageing population and patients with chronic illnesses. This research theme is therefore closely aligned with the IGHI’s vision of providing safe, effective and accessible technologies for both developed and developing countries.

Some of our latest works were exhibited at the 2015 Royal Society Summer Science Exhibition.


BibTex format

author = {Modi, HN and Singh, H and Fiorentino, F and Orihuela-Espina, F and Athanasiou, T and Yang, G-Z and Darzi, A and Leff, DR},
doi = {10.1001/jamasurg.2019.2552},
journal = {JAMA Surgery},
title = {Association of residents' neural signatures with stress resilience during surgery},
url = {http://dx.doi.org/10.1001/jamasurg.2019.2552},
volume = {154},
year = {2019}

RIS format (EndNote, RefMan)

AB - Importance: Intraoperative stressors may compound cognitive load, prompting performance decline and threatening patient safety. However, not all surgeons cope equally well with stress, and the disparity between performance stability and decline under high cognitive demand may be characterized by differences in activation within brain areas associated with attention and concentration such as the prefrontal cortex (PFC). Objective: To compare PFC activation between surgeons demonstrating stable performance under temporal stress with those exhibiting stress-related performance decline. Design, Setting, and Participants: Cohort study conducted from July 2015 to September 2016 at the Imperial College Healthcare National Health Service Trust, England. One hundred two surgical residents (postgraduate year 1 and greater) were invited to participate, of which 33 agreed to partake. Exposures: Participants performed a laparoscopic suturing task under 2 conditions: self-paced (SP; without time-per-knot restrictions), and time pressure (TP; 2-minute per knot time restriction). Main Outcomes and Measures: A composite deterioration score was computed based on between-condition differences in task performance metrics (task progression score [arbitrary units], error score [millimeters], leak volume [milliliters], and knot tensile strength [newtons]). Based on the composite score, quartiles were computed reflecting performance stability (quartile 1 [Q1]) and decline (quartile 4 [Q4]). Changes in PFC oxygenated hemoglobin concentration (HbO2) measured at 24 different locations using functional near-infrared spectroscopy were compared between Q1 and Q4. Secondary outcomes included subjective workload (Surgical Task Load Index) and heart rate. Results: Of the 33 participants, the median age was 33 years, the range was 29 to 56 years, and 27 were men (82%). The Q1 residents demonstrated task-induced increases in HbO2 across the bilateral ventrolateral PFC (VLPFC) and right dorsolateral P
AU - Modi,HN
AU - Singh,H
AU - Fiorentino,F
AU - Orihuela-Espina,F
AU - Athanasiou,T
AU - Yang,G-Z
AU - Darzi,A
AU - Leff,DR
DO - 10.1001/jamasurg.2019.2552
PY - 2019///
SN - 2168-6254
TI - Association of residents' neural signatures with stress resilience during surgery
T2 - JAMA Surgery
UR - http://dx.doi.org/10.1001/jamasurg.2019.2552
UR - https://www.ncbi.nlm.nih.gov/pubmed/31389994
UR - https://jamanetwork.com/journals/jamasurgery/fullarticle/2740793
UR - http://hdl.handle.net/10044/1/72476
VL - 154
ER -