Centre for Inflammatory Disease

Investigating the causes and mechanisms of organ damage in a range of autoimmune and inflammatory conditions

The Centre for Inflammatory Disease brings together a diverse group of clinical and non-clinical experts who study the causes and mechanisms of organ damage in a range of autoimmune and inflammatory conditions.

Key research areas include autoimmunity, complement, macrophage biology, tumour immunology, vascular inflammation, skin immunology and renal pathology. Our methodologies range from in vitro approaches; in vivo modelling of inflammation and autoimmunity; clinical trials and systems biology. Clinically we have expertise in Systemic Lupus Erythematosus; C3 glomerulopathy; Glomerulonephritis, Diabetic nephropathy, Chronic kidney disease, Chronic Granulomatous Disease and Vasculitis.

Funding sources include the Wellcome Trust, Medical Research Council, Versus Arthritis, British Heart Foundation, Kidney Research UK, and the National Institute for Health Research.

Professor Matthew Pickering

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Professor Matthew Pickering Director
Send email+44 (0)20 3313 2315

Bio

Matthew Pickering is Professor of Rheumatology and a Wellcome Trust Senior Fellow in Clinical Science. His research interest is complement and the kidney and his clinical expertise includes systemic lupus erythematous and complement deficiency states.

Location

9N12, Commonwealth Building, Hammersmith Campus

Professor Danny Altmann

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Professor Danny Altmann Professor of Immunology
Send email+44 (0)20 3313 8212

Bio

Danny Altmann heads a lab at the Hammersmith Hospital Campus of Imperial, with expertise in the HLA system, antigen discovery, T cell subsets and NK cells.

Location

5S5C, Commonwealth Building, Hammersmith Campus
Dr Jacques Behmoaras

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Dr Jacques Behmoaras Reader
Send email+44 (0)20 3313 2339

Bio

Jacques Behmoaras' group applies systems-genetics approaches in macrophage immune function and metabolism related to complex inflammatory diseases.

Location

Currently based at Duke-NUS Medical School, Singapore
Professor Marina Botto

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Professor Marina Botto Director of Bioservices, Professor of Rheumatology
Send email+44 (0)20 3313 2316

Bio

Marina Botto is Professor of Rheumatology, Honorary Consultant at Imperial College Healthcare NHS Trust, and Director of Bioservices at Imperial College London. Her research focuses on complement biology and autoimmunity, specifically systemic lupus erythematous.

Location

9N10, Commonwealth Building, Hammersmith Campus
Professor Petter Brodin

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Professor Petter Brodin Garfield Weston Chair of Neonatology and Professor of Paediatric Immunology
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Bio

Professor Brodin’s research centres on understanding factors that shape human immune system variation in health and disease, and developing new experimental and computational tools to study human immune systems in more comprehensive and holistic ways. As an active paediatrician specialising in pediatric immunology, his research also explores how and when the immune system is shaped by environmental exposures early in life.

Location

Hammersmith Campus
Professor Terence Cook

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Professor Terence Cook Emeritus Professor
Send email+44 (0)20 3313 2009

Bio

Terence Cook is Emeritus Professor and Honorary Consultant Renal Pathologist in North West London Pathology. His research interests are mechanisms of kidney injury in glomerular disease, particularly glomerulonephritis associated with abnormal control of complement activation.

Location

9N9, Commonwealth Building, Hammersmith Campus
Dr Alice Denton

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Dr Alice Denton MRC Career Development Fellow
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Bio

Dr Alice Denton is an MRC Career Development Fellow with a background in the regulation of adaptive immunity. Her research focusses on how fibroblasts govern the initiation and development of protective immunity.

Location

9N15a, 9th Floor, Commonwealth Building, Hammersmith Campus
Professor Guido Franzoso

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Professor Guido Franzoso Professor of Inflammation and Signal Transduction
Send email+44 (0)20 3313 8421

Bio

Guido Franzoso is Professor and Chair of Signal Transduction and Inflammation and holds an Honorary position at Imperial College NHS Trust. His research interest is the regulation and function of NF-κB transcription factors.

Location

5N1A, Commonwealth Building, Hammersmith Campus
Professor Liz Lightstone

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Professor Liz Lightstone Professor of Renal Medicine
Send email+44 (0)20 3313 2309

Bio

Liz Lightstone is Professor of Renal Medicine and Honorary Consultant Physician in the Renal Directorate at Imperial College Healthcare NHS Trust. She undertakes translational research in glomerulonephritis, notably lupus nephritis and C3GN, as well as in pregnancies in women with kidney diseases.

Location

5S5e, Commonwealth Building, Hammersmith Campus
Dr Tiago Cunha Luis

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Dr Tiago Cunha Luis Sir Henry Dale Fellow
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Bio

Dr Tiago Cunha Luis investigates the molecular mechanisms by which the bone marrow microenvironment regulates haematopoietic stem cells (HSC) function during regeneration and in the development of haematological malignancies.

Location

9N4b, 9th Floor, Commonwealth Building, Hammersmith Campus
Dr Stephen McAdoo

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Dr Stephen McAdoo Honorary Clinical Senior Lecturer
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Bio

Dr Stephen McAdoo holds an Imperial College Clinician Researcher Fellowship, and is an Honorary Consultant Nephrologist at Imperial College Healthcare NHS Trust. His clinical and research interests are in autoimmune kidney diseases, with a particular focus on crescentic glomerulonephritis and systemic vasculitis.

Location

Renal Medicine, Hammersmith Hospital, Hammersmith Campus
Dr Leticia Monin Aldama

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Dr Leticia Monin Aldama Advanced Research Fellow
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Location

Commonwealth Building,
Hammersmith Campus
Dr James Peters

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Dr James Peters Reader in Rheumatology and UKRI Innovation Fellow at Health Data Research UK
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Bio

James Peters' research lies at the interface of molecular epidemiology, computational biology and clinical medicine. Our focus is understanding the molecular and cellular basis of immune-mediated inflammatory diseases using a combination of genomics, transcriptomics and proteomics.

Location

Commonwealth Building, Hammersmith Campus
Dr Maria Prendecki

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Dr Maria Prendecki MRC Clinician Scientist Fellow
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Bio

Maria Prendecki's research focus is to understand how neutrophil heterogeneity contributes to the pathogenesis and spectrum of disease in ANCA associated vasculitis (AAV).

Location

5th Floor, Commonwealth Building, Hammersmith Campus
Professor Charles Pusey

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Professor Charles Pusey Emeritus Professor of Medicine
Send email+44 (0)20 3313 2308

Bio

Charles Pusey is Emeritus Professor of Medicine, and Honorary Consultant Physician in the Renal Directorate at Imperial College Healthcare NHS Trust. He is a clinician scientist with a particular interest in autoimmune renal disease, including primary systemic vasculitis.

Location

5N2, Commonwealth Building, Hammersmith Campus
Dr Candice Roufosse

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Dr Candice Roufosse Clinical Reader in Renal Pathology
Send email+44 (0)20 3313 3280

Bio

Dr Candice Roufosse is Clinical Reader in Renal Pathology and Honorary Consultant in Renal and Transplant Cellular Pathology North West London Pathology (affiliated to Imperial College Healthcare NHS Trust). She carries out translational research in renal and transplant pathology.

Location

Commonwealth Building, Hammersmith Campus
Dr Sophie Rutschmann

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Dr Sophie Rutschmann Reader in Immunology
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Bio

Sophie Rutschmann is a non-clinical Senior Lecturer with a research background in genetics and immunology. In the Department, she leads the MSc Immunology and advises on the education strategy. In the Faculty of Medicine, she is the Academic Lead for Postgraduate Education.

Location

9N4b, Hammersmith Hospital, Hammersmith Campus
Dr Eleanor Sandhu

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Dr Eleanor Sandhu Honorary Clinical Research Fellow
Send email+44 (0)20 3313 3980

Bio

Dr Eleanor Sandhu is a Consultant Nephrologist at Imperial College Healthcare NHS Trust. Her research interest is in the neurobiology of the body-brain axis in modifying salt intake and its translation to the clinical care of renal patients.

Location

5N8A, 5th Floor, Commonwealth Building, Hammersmith Campus
Professor Jessica Strid

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Professor Jessica Strid Professor of Cellular Immunology
Send email+44 (0)20 3313 1475

Bio

Jessica Strid is a Professor of Cellular Immunology. Her research group studies immune-surveillance in epithelial tissues, principally the skin, and focus on understanding the role of tissue resident immune cells in regulating epithelial cell homeostasis, repair and carcinogenesis.

Location

9N15B, Commonwealth Building, Hammersmith Campus
Professor Frederick Tam

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Professor Frederick Tam Ken and Mary Minton Chair of Renal Medicine
Send email+44 (0)20 3313 2354

Bio

Professor Frederick Tam's research has been developing non-invasive biomarkers and novel anti-inflammatory therapies for kidney diseases, including diabetic nephropathy, glomerulonephritis and rejection of kidney transplant. His group integrates laboratory mechanistic study with clinical trials.

Location

5N, 8C, Commonwealth Building, Hammersmith Hospital, Hammersmith Campus
Dr Fiona Watt

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Dr Fiona Watt Clinical Reader in Rheumatology
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Bio

Fiona Watt is a Clinical Reader, Honorary Consultant Rheumatologist and a UKRI Future Leaders Fellow. Her clinical and research interest is in osteoarthritis, particularly clinical & biological factors which predict outcome in high-risk groups and the development of new tests and treatments for the condition.

Location

9th Floor, Commonwealth Building, Hammersmith Campus
Dr Michelle Willicombe

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Dr Michelle Willicombe Clinical Reader in Kidney Transplantation
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Bio

Dr Michelle Willicombe is a Clinical Reader in Kidney Transplantation and Honorary Consultant Nephrologist at Imperial College Healthcare NHS Trust, with clinical expertise in transplantation. Her research interest is in the prevention and treatment of antibody-mediated transplant rejection.

Location

Commonwealth Building, Hammersmith Campus
Dr Kevin Woollard

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Dr Kevin Woollard Honorary Senior Lecturer
Send email+44 (0)20 3313 2357

Bio

Dr Woollard is Honorary Senior Lecturer and Principal Scientist, Pre-clinical Renal Bioscience Lead at AstraZeneca (Cambridge). His lab studies the immunobiology of inflammatory kidney and reno-cardiac disease.

Location

9N15C, Commonwealth Building, Hammersmith Campus