Collection of Tissue 


Anyone wishing to collect and store human material for research purposes at Imperial College London or Imperial College Healthcare Trust (ICHT) must register their collection with the Tissue Bank, unless the collection and storage of that material is currently covered by project specific REC/Health Research Authority (HRA) approval e.g. a HRA cohort study or clinical trial. If the collection has its own REC approval, the study must be registered on the JRCO's DOCUMAS system, and the appropriate tab on tissue collection completed.
At the end of the REC approval for the study, samples may be retained by registering as a sub-collection with the Tissue Bank.


There are three main types of sub-collection

  1. Those that use generic consent materials that are approved under the Tissue Bank's own REC approval.
  2. Those that have used consent materials approved under a different REC approval, and that the original REC approval has lapsed (e.g. a clinical trial that has finished recruiting but the Trial Management Committee wish to retain the human samples collected as part of the trial).
  3. Collections of human material that have been collected outside the UK or are being supplied by other institutions in the UK.

An application to host a sub-collection can be made on the ICHTB database. If you are a Principal Investigator who already holds a sub-collection, just log on to the database using your College username and password and click apply to hold a sub-collection. If you wish to open your first sub-collection please contact the Tissue Bank so that we can register you appropriately. 

Information on what is required to set up and run a sub-collection can be found in the  document Sub-collection Management for Persons Designated and Principal Investigators.

Registration of a sub-collection enables collection and storage of human samples. Specific applications to use the samples in research must be made to the Tissue Bank and are approved by an Application Review Panel. For more information, see Using Human Samples in Research.