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This one-year research-based postgraduate course is based mainly in structural biology labs at the South Kensington campus. The course provides in-depth training of all major structural molecular biology techniques including its applications in drug discovery. It is an excellent training course for students to pursue a career in research with a focus on structural biology..

Knowing the structure of a protein is vital to understand how the protein works. With many structure determination techniques becoming semi-automatic and routine, there will be a requirement for structural biology researchers who can understand how to use complementary techniques to derive biological function from structure. It is therefore essential that trained structural biologists (for both academia and industry) have a solid background across all macromolecular structural determination techniques.

This Masters in Research (MRes) seeks to build such a solid foundation. Students will spend the majority of the year in laboratory-based research in one or two structural biology labs at, or associated with, Imperial, with opportunities to learn a wide range of skills in biological NMR, electon cryomicroscopy, structural bioinformatics, molecular dynamics, x-ray crystallography, or mass spectrometry. Students also attend a series of lectures covering protein structural principles and structure determination techniques, and workshops on skills needed to succeed in research including networking, time management, writing, and wellbeing.

Workshops and seminars in transferable skills are organised by the Graduate School.

More information

Course Structure

  • Practical laboratory experience
  • Two independent research projects
  • Taught courses in principles of structural molecular biology
  • Specialist lectures in cutting-edge research
  • Macromolecular structure and function
  • Transferable skills

Techniques covered include:

  • X-ray crystallography
  • Electron cryomicroscopy
  • Nuclear Magnetic Resonance Spectroscopy
  • Mass Spectroscopy and glycobiology
  • Structure-function relationship and protein enzymology
  • Structural Bioinformatics

Research areas conducted by supervisors:

  • Membrane protein structure-function
  • Human disease and infection
  • Photosynthesis and bioenergetics
  • Transcriptional regulation and mechanism
  • Enzyme catalysis
  •  Macromolecular machines

Workshops and Master Classes in transferable skills are organised by the Graduate School.

Entry Requirements

An Upper Second Class Honours degree or equivalent is required for entry onto this course

The College English requirements can be found here: http://www.imperial.ac.uk/study/pg/apply/requirements/english/

How to Apply

Applications are made online at: http://www.imperial.ac.uk/study/pg/apply/

Links with Employers

Imperial College works closely with employers and industry, including Industrial Advisory Panels to design Master’s courses which provide graduates with technical knowledge, expe rtise and transferable skills and to encourage students to take internships and placements. All Master’s courses are designed with employer needs in mind with some Master’s courses accredited by Professional, Statutory and Regulatory Bodies.

Fees and Funding

Tuition Fees information

Scholarships information

Previous years

MRes in Structural Molecular Biology cohort; academic year 2019-20
MRes in Structural Molecular Biology cohort; academic year 2019-20

MRes in Structural Molecular Biology cohort; academic year 2017-18
MRes in Structural Molecular Biology cohort; academic year 2017-18