Vector control remains at the forefront of the fight against malaria. The unprecedented expansion of long-lasting insecticide treated bednets and indoor residual spraying programmes has reduced the burden of disease across the world. However, there is a growing realisation that the effectiveness of these tools is under threat.

Insecticide resistance is a key concern for all malaria control programmes though it is still unclear what public health impact it will have. Working with the World Health Organisation and the Innovative Vector Control Consortium we are using mathematical models to predict the public health impact of different types of insecticide resistance from entomological data. In collaboration with the Liverpool School of Tropical Medicine we are directly assessing whether pyrethroid resistance can explain why clinical incidence in field sites in Burkina Faso has remained high despite widespread use of long-lasting insecticide treated bednets.