About us

The National Institute for Health Research (NIHR) has funded the development of a number of Health Protection Research Units (HPRU) in key priority areas. These research units are collaborations between Universities, Public Health England (PHE) and other partner organisations and aim to provide centres of excellence in multi-disciplinary health protection research.

The NIHR HPRU in Healthcare Associated Infections (HCAI) and Antimicrobial Resistance (AMR) at Imperial College London, started on 1 April 2014 and has now renewed five-year funding from 1 April 2020. Our HPRU in HCAI and AMR has as its partners:

Our HPRU recognises the different skills required to address the threat of AMR and HCAIs, and it brings together researchers from a range of disciplines and professions (including doctors, engineers, epidemiologists, microbiolosts, pharmacists, behavioural scientists, economists, and nurses). Our approach to addressing HCAIs and AMR is via four complementary themes:

  1. Priority pathogens
  2. Precision prescribing
  3. Practice, design and engineering
  4. Population health and policy


Our People


Alison Holmes

The principal areas of Professor Holmes' research are in hospital epidemiology and infection prevention and control, including the field of antibiotic stewardship to address the threat of antimicrobial resistance. Her work addresses infection management, patient safety and public health within acute healthcare and provides a clear example of applied research in healthcare delivery. In particular, Professor Holmes has demonstrated how patient-focused research can have a powerful and rapid impact on the health of the patients concerned, with wider implications for the NHS as a whole.

A further element of her work also involves investigating models of health care and methods of improving systems to ensure best practice and a reduction in healthcare associated infection.

Find out more about Professor Holmes

PHE Lead

Dr Matthew Ellington

Research active clinical scientist with over 15 years experience at the clinical / research interface and expertise investigating the factors underpinning antimicrobial resistance. Dr Ellington sits on the European Committee on Antimicrobial Susceptibilty Testing (EUCAST) subcomittee on WGS for AST and the British Society for Antimicrobial Chemotherapy's (BSAC) standing committee on antimicrobial susceptibility testing.

Find out more about Dr Ellington

Research staff

Bernard Hernandez Perez

Bernard Hernandez Perez

Bernard Hernandez Perez
HPRU Affiliate, Research Associate

Hannah Lishman

hannah lishman

Hannah Lishman
HPRU Affiliate, Honorary Researcher

Professional Staff

Farzan Ramzan

Farzan Ramzan

Farzan Ramzan
Data manager

Scientific Advisory Board

SAB image

Other HPRUs at Imperial

Chemical and Radiation Threats and Hazards

Led by Imperial researchers

Blood Borne and Sexually Transmitted Infections

Led by Imperial researchers