Our pioneering research into the diagnosis, prevention and treatment of heart disease is based at the National Heart and Lung Institute (NHLI).
Increasing our understanding of the basic pathophysiological mechanisms of cardiovascular disease and applied bioengineering will continue to direct translational research, leading to superior, more targeted therapies.
Major research focuses
- Fundamental investigations on the mechanisms of cardiac and vascular disease
- Genetics of cardiovascular disease
- New cell and gene therapies
- Clinical trials at the International Centre for Circulatory Health
We host state of the art facilities that enable us to carry out world leading cardiovascular research. Within our new Imperial Centre for Translational and Experimental Medicine, we host two British Heart Foundation centres:
Biomedical Research Unit (BRU)
The Imperial NIHR Cardiovascular Biomedical Research Unit (BRU) at the Royal Brompton and Harefield NHS Trust enables us to translate our advances in cutting edge research seamlessly into benefits for patients with heart disease. We aim to do this within five years.
Examples of our work within the BRU:
- gene therapies in patients with problematic heart failure
- diagnosis with next generation diagnostic genetics
- advanced Magnetic Resonance to dissect problems of structure of the heart in patients with inherited cardiomyopathy
- International Centre for Circulatory Health
- Imperial Clinical Trials Unit
- NIHR Wellcome Trust Imperial Clinical Research Facility
Research in this area is supported by funding from many sources, including UK research councils, charities, including the British Heart Foundation (BHF), Heart Research UK, Arthritis Research UK and the Wellcome Trust, and commercial sources.