The core FACS facility on St. Mary’s Paddington campus of Imperial College London was created by a Wellcome strategic award that established the Centre for Respiratory Infection in 2009. In 2013 Imperial College incorporated the laboratory as a multi-user core facility and funded the relocation and construction of a custom-built FACS laboratory. The Facility has since received further support from the Medical Research Council (MRC).
This core facility is a resource open to all researchers at Imperial, and because of the high level of service provided, attracts a growing number of users from across London and beyond. Our ability to sort category-2-level pathogens and cells means the facility has developed great expertise in working with infectious material, such as fresh patient material, infected samples or pure pathogens.
Dr Fiona Culley and Professor Peter Openshaw are the academic leads, while the facility is managed by Dr Yanping Guo - a highly qualified and experienced flow cytometry specialist who provides a sorting service and technical assistance, and can advise and assist with experimental design and execution.
We provide in-depth on-site user training, and all equipment is fully bookable using an online calendar. The facility promotes its services by offering seminars and workshops, and by personal communication during meetings and laboratory seminars. Our user committee makes recommendations for facility priorities and policy formulation. The St. Marys FACS core facility provides a shared network drive with a size of 200GB for user data transfer and short-term storage. Users can have access to various software tools for data analysis.