Vaccines
Theme lead
The Centre retains a strong focus on vaccine epidemiology across multiple disease areas, which span the whole development pipeline from discovery science, clinical trials, through to impact monitoring and programme optimisation.
At the discovery stage, there is a strong focus on the early life intestinal microbiome and its relationship with vaccine-induced immunity for poliovirus, rotavirus, enterovirus and typhoid. At the intermediate stage, we inform the development of new prevention tools, including new vaccines against sexually transmitted infections, by informing the design, conduct, and interpretation of pivotal clinical trials, and defining the desired product characteristics needed to meet priority public health goals to support investment in product development.
We continue to undertake a substantial portfolio of research on the public health impact and evaluation of vaccines post-licensure, including vaccination against HPV, HIV and other sexually transmitted infections and support for the Global Polio Eradication Initiative and GAVI on the public health impact and cost-effectiveness of malaria and yellow fever vaccines.
The Centre conducts extensive research into interventions which aim to improve population health, including mass drug administration programmes, combination of biological, behavioural and structural prevention interventions, and health education initiatives to promote behaviour modification and infectious disease vector control and elimination techniques.
Researchers combine state-of-the-art mathematical, statistical and epidemiological methods with high-quality data to answer a wide range of policy relevant questions.
Vaccine and intervention research conducts multidisciplinary and collaborative research with a broad range of international research groups, centers and institution and stakeholders, including the World Health Organization (WHO), HIV Prevention Trial Network (HPTN) and Centers for Disease Control and Prevention (CDC), in order to understand and reduce the burden of major infections and diseases and accelerate the development and efficient implementations of prevention interventions
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Hosted initiatives and groups
Discover more about our work in this theme through our various initiatives and research groups:
- NIHR Health Protection Research Unit in Modelling and Health Economics
- UNAIDS Reference Group on Estimates, Modelling and Projections
- London Centre for Neglected Tropical Disease Research
- Vaccine Impact Modelling Consortium (VIMC)
- Global Health & Development Group
- Health Economics Group
- Bacterial Evolutionary Epidemiology Group
Disease areas
Learn more about our work in vaccines in our focus disease areas:
People
Professor Neil Ferguson

Professor Neil Ferguson
Professor of Mathematical Biology and Head of Department of Infectious Disease Epidemiology
Professor Sir Roy Anderson

Professor Sir Roy Anderson
Professor in Infectious Disease Epidemiology
Dr Nimalan Arinaminpathy (Nim Pathy)

Dr Nimalan Arinaminpathy (Nim Pathy)
Reader in Mathematical Epidemiology
Dr Marc Baguelin

Dr Marc Baguelin
Lecturer
Dr Isobel Blake

Dr Isobel Blake
Lecturer
Professor Marie-Claude Boily

Professor Marie-Claude Boily
Professor of Mathematical Epidemiology
Dr Thomas Churcher

Dr Thomas Churcher
Senior Lecturer
Dr Nicholas Croucher

Dr Nicholas Croucher
Senior Lecturer in Bacterial Genomics
Professor Christl Donnelly

Professor Christl Donnelly
Professor of Statistical Epidemiology
Dr Ilaria Dorigatti

Dr Ilaria Dorigatti
Lecturer
Dr Tini Garske

Dr Tini Garske
Senior Lecturer
Professor Azra Ghani

Professor Azra Ghani
Chair in Infectious Disease Epidemiology
Professor Nicholas Grassly

Professor Nicholas Grassly
Professor of Infectious Disease & Vaccine Epidemiology
Professor Timothy Hallett

Professor Timothy Hallett
Professor of Global Health
Dr Thibaut Jombart

Dr Thibaut Jombart
Senior Lecturer
Professor Steven Riley

Professor Steven Riley
Professor of Infectious Disease Dynamics
Dr Hugo Turner

Dr Hugo Turner
Lecturer
Prof Peter White

Prof Peter White
Professor in Public Health Modelling