@article{Zhang:2014:10.1186/ar4455,
author = {Zhang, KY and Kedgley, AE and Donoghue, CR and Rueckert, D and Bull, AMJ},
doi = {10.1186/ar4455},
journal = {Arthritis Research and Therapy},
pages = {1--9},
title = {The relationship between lateral meniscus shape and joint contact parameters in the knee: a study using data from the Osteoarthritis Initiative},
url = {http://dx.doi.org/10.1186/ar4455},
volume = {16},
year = {2014}
}

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TY  - JOUR
AB  - IntroductionThe meniscus has an important role in force transmission across the knee, but a detailed three-dimensional (3D) morphometric shape analysis of the lateral meniscus to elucidate subject-specific function has not been conducted. The aim of this study was to perform 3D morphometric analyses of the lateral meniscus in order to correlate shape variables with anthropometric parameters, thereby gaining a better understanding of the relationship between lateral meniscus shape and its load-bearing function.MethodsThe lateral meniscus (LM) was manually segmented from magnetic resonance images randomly selected from the Osteoarthritis Initiative (OAI) non-exposed control subcohort. A 3D statistical shape model (SSM) was constructed to extract the principal morphological variations (PMV) of the lateral meniscus for 50 subjects (25 male and 25 female). Correlations between the principal morphological variations and anthropometric parameters were tested. Anthropometric parameters that were selected included height, weight, body mass index (BMI), femoral condyle width and axial rotation.ResultsThe first principal morphological variation (PMV) was found to correlate with height (r = 0.569), weight (r = 0.647), BMI (r = 0.376), and femoral condyle width (r = 0.622). The third PMV was found to correlate with height (r = 0.406), weight (r = 0.312), and femoral condyle width (r = 0.331). The percentage of the tibial plateau covered by the lateral meniscus decreases as anthropometric parameters relating to size of the subject increase. Furthermore, when the size of the subject increases, the posterior and anterior horns become proportionally longer and wider.ConclusionThe correlations discovered suggest that variations in meniscal shape can be at least partially explained by the levels of loads transmitted across the knee on a regular basis. Additionally, as the size of the subj
AU  - Zhang,KY
AU  - Kedgley,AE
AU  - Donoghue,CR
AU  - Rueckert,D
AU  - Bull,AMJ
DO  - 10.1186/ar4455
EP  - 9
PY  - 2014///
SN  - 1478-6354
SP  - 1
TI  - The relationship between lateral meniscus shape and joint contact parameters in the knee: a study using data from the Osteoarthritis Initiative
T2  - Arthritis Research and Therapy
UR  - http://dx.doi.org/10.1186/ar4455
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335148700026&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://arthritis-research.biomedcentral.com/articles/10.1186/ar4455
UR  - http://hdl.handle.net/10044/1/19136
VL  - 16
ER  - 

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