Towards whole brain functional imaging in freely moving subjects
The measurement of functional activity in the brain is crucial to understanding how this structure works. Functional ultrasound imaging (fUS) is an exciting new technique that has demonstrated its feasibility in vivo, and has potential for whole brain functional imaging in freely moving subjects.
This project is the first step towards such a portable brain imaging system. The aim is to develop and evaluate an initial fUS system using a customized ultrasound probe within a helmet, in combination with microbubble contrast agents and advanced image reconstruction algorithms for increased imaging sensitivity. Evaluation of the system will be performed by in vitro phantoms and imaging sensory-evoked brain activity.