Introduction to stream-specific compulsory modules

Genes Drugs and Stem Cells - Novel Therapies

Introduction to stream-specific compulsory modules

Genes and Nucleic Acid-Based Therapies - Griesenbach

The gene and nucleic acid-based therapies stream will cover a range of disease indications for which gene therapy has been, or is being, developed.

This module will allow in depth discussion on the need for careful selection of gene therapy vectors for specific disease indications as well as problems encountered along the way. 

Information on stream Genes and Nucleic Acid-Based Therapies

Genes and Nucleic Acid-Based Therapies - Griesenbach

Professor Uta Griesenbach provides an overview of her stream specific core module.

The gene and nucleic acid-based therapies stream will cover a range of disease indications for which gene therapy has been, or is being, developed.

This module will allow in depth discussion on the need for careful selection of gene therapy vectors for specific disease indications as well as problems encountered along the way. 

Information on stream Regenerative Medicine

Regenerative Medicine - Rankin

Professor Sara Rankin provides an overview of her stream specific core module.

In this stream lectures will progress from covering fundamental developmental and stem cell biology, through to the practicalities of clinical trials and the commercialization of stem cell therapies. 

At Imperial we are very keen to engage the public with our science and therefore in this stream we have lectures and a workshop  covering innovative ways to engage the public in science.

Information on stream New Horizons in Pharmacology

New Horizons in Pharmacology - Mitchell

Professor Jane Mitchell provides an overview of her stream specific core module.

In this stream lectures will include the history of drugs, from examples like aspirin which is centuries old, right through to new types of drugs made from antibodies or delivered in stem cells. Providing students with a full understanding of drugs from their early conception right up to the latest discoveries.

Our course includes lectures from Imperial College and other world leading institutions that are at the cutting edge of drug development. We also include lectures from professionals in the drug industry and who specialize in the ethics and financial aspects of research and bringing a drug to the market. 


Handbooks

This page is currently under construction and no handbooks are available yet. Soon you will be able to select your programme below to view and download the handbook.

Healthcare, genes, genomics

Students in library

Cardiovascular and Respiratory Healthcare

Handbook coming soon...

Healthcare, genes, genomics

Doctor looks at screen

Innovations in Cardiological Science

Handbook coming soon...


Further information on programme modules

 

Genes Drugs and Stem Cells - Novel Therapies

Modules

Compulsory modules

Science and Research Skill Module:

Basic ethical principles related to pre-clinical and clinical research (including special consideration for working with children), the human tissue act and relevant tissue governance in addition to basic statistics and experimental design will be taught. A number of transferable and research skill sessions will be timetabled including note taking, efficient reading, database searches and referencing, oral and written presentation skills and critical appraisal of research papers in form of journal clubs. An important aspect of this model is also to make students aware of commercialisation strategies including the importance of IP protection and patents as well as the health economy. These issues will be discussed from an academic and industry view. In addition the students will be familiarised with all necessary safety regulations for working at Imperial College.

Key concepts in Gene and Nucleic Acid-Based Therapies:

Students will be introduced to the key concepts of human genetics and genomics that underpin the development of gene and nucleic acid-based therapies. This includes lectures on monogenic and complex diseases, the complexities of genotype/phenotype correlations, key principles of gene regulation as well as generation of suitable animal models to mimic human disease. Students will also be introduced to ethical considerations related to genetic testing and data release. In addition students will be familiarised with basic tools related to gene and nucleic acid-based therapies such as commonly used viral and non-viral vectors and vector production methods. A couple of representative disease targets will also be discussed. PCR-based genotyping will be taught in a practical. Transferrable skills will be developed when preparing and delivering debates covering controversial topics within the subject area. 

Key concepts in Regenerative Medicine:

This module will focus on providing the basis and key concepts of  areas essential to Regenerative medicine. Lectures and journal clubs will focus on the following topics:  Developmental Biology, Stem cell Biology, Animal models for regenerative medicine, Clinical trials. The series of lectures, with intercalated workshops and journal clubs, will take the students from the very basic concepts of development and of the current knowledge about stem cells, to the experimental models which have been developed to investigate the use of stem cells in disease. The module will then move to human studies, discussing clinical trials (including cell therapy) to provide a methodological prospective and to then review the current status of trials using regenerative medicine. The course will also provide an introduction to Biomaterials for regenerative medicine. The module will discuss and describe different strategies to engage the public in the research, ethics and clinical translation of regenerative medicine.

Key concepts in New Horizons in Pharmacology

The aim of the Key concepts in Pharmacology module is to provide the student with a basic understanding of how drugs target disease, disease mechanisms and how the drug development process has evolved over the history of pharmacology, how it will change in the future and differs for common versus rare conditions. The cutting edge content of the course will assist the student in taking a more proactive role in the development of novel therapeutic agents and assessment of their safety.

Advanced studies module

Advanced studies in Gene and Nucleic Acid-Based Therapies:

The content of this module will build on teaching delivered in the stream-specific core module (Key Concepts in Gene and Nucleic acid-based therapies). This module will comprehensively cover the current know-how on gene and nucleic acid based therapies and in combination with the project provide student with adequate tools to pursue further postgraduate studies or a non-academic career in the field. Students will become familiar with a range of disease specific clinical application related to gene and nucleic acid-based therapies to gain an advanced understanding. This will involve familiarisation with principles related to good clinical practice (GCP) and other regulatory requirements, as well as the concepts of GMP manufacturing. The history and development of the first approved gene therapy product will be discussed. Through relevant practicals, student will gain experience in techniques relevant for the 6 month research projects.

Advanced studies in Regenerative Medicine:

In this module students will learn about the tools and technologies utilised in the field of regenerative medicine and the use of stem cells to develop disease models in culture (so called disease in a dish). Lectures will cover cutting edge research and new patents relating to regenerative pharmacology, covering the molecular pathways and drugs being used for stem cell differentiation in vitro and for the mobilization and activation of stem cells in vivo. The basic science of differentiating stem cells into cardiac cells will be covered in addition to the practicalities of scale up, to generate robust and reproducible cultures. In addition, the module will focus on tissue engineering and translational strategies for regenerative medicine.

Advanced studies in New Horizons in Pharmacology

The content of this module will build on teaching delivered in the key concept module. This module will comprehensively cover how Pharmacology continues to identify new endogenous pathways (eg cytokines) that can be targeted to develop new drugs. In addition the idea of how nanomedicine approaches are being used to make new formulations of drugs and what this means in terms of testing efficacy and toxicity will be addressed. Finally, principals of personalised medicine in current clinical practice and into the future will be covered. This in combination with the project will provide student with adequate tools to pursue further postgraduate studies or a non-academic career in the field.

6 month research project

Following successful completion of the 5 taught modules, student will conduct a 6 months research project. The project will be related to one of the three course streams; Gene and Nucleic Acid-based therapies, Regenerative Medicine or  New Horizons in Pharmacology. Students will join an established research laboratory and will conduct work supervised by academic staff. At the end of the project students will prepare a project report (approximately 10,000 words) and a oral presentation.


Cardiovascular and Respiratory Healthcare

Cardiovascular and Respiratory Healthcare modules

Core modules

Cardiovascular and respiratory healthcare core science:

This module provides an overview of cardiovascular and respiratory health and wellbeing. It covers cardiovascular and respiratory anatomy and physiology, the epidemiology of cardiovascular and respiratory disease, the concepts of health and well-being and physiological changes associated with haemorrhage, immobility and bed rest. It will also discuss the integration of anatomy and physiology to the delivery of person-centred healthcare.

Study design:

This module covers the principles and practice of quantitative and qualitative research. It will cover key issues in critically evaluating various methodologies and provide a strong foundation for conducting your own research.

Reflection and evaluation of clinical practice:

This module will help you develop a broad understanding of the practice of cardiovascular and respiratory healthcare. You will have an opportunity to observe relevant clinical practice, reflect on the realities and limitations that professionals and service providers’ face and identify recommendations for service improvement.

Optional modules

Clinical examination and history taking:

This module discusses how to perform a systematic cardiovascular and respiratory clinical history and examination and explore its contribution to the clinical management plan. You will develop your skills in performing a clinical history and examination in relation to the assessment and management of the patient with cardiovascular and respiratory disease. 

Innovation in Management of Cardiovascular Disease: Acute and Community:

This module will provide a comprehensive background to develop understanding of the therapeutic interventions (pharmacological and non-pharmacological) for commonly encountered cardiovascular diseases. Teaching will concentrate on the aetiology, pathophysiology and treatment of common cardiovascular conditions such as coronary heart disease, cardiomyopathies and arrhythmias. You will be introduced to diagnostic evaluation, including basic imaging, as well as – where relevant - genetic tests. You will review the contemporary use of pharmacological and device therapies in personalising clinical practice and will also learn about the management of anxiety and depression and how to optimise self-care.

Heart failure - Prevention AND management:

This module will explore the state-of-the-art knowledge of the prevention and management of heart failure. It will cover the epidemiology, aetiology and altered physiology, the heart failure trajectory symptoms and prognosis. The evidence for pharmacological and non-pharmacological management will be explored alongside life-style advice and self-care. The common comorbidities associated with heart failure will also be covered. Key issues in setting up a heart failure service will be discussed. For nurses undertaking this module: the module content is mapped to the European Heart Failure Nurse Curriculum.

Cardiovascular health - prevention and rehabilitation: 

This module will consider the primary and secondary prevention of cardiovascular disease and rehabilitation of people with established heart disease. Different approaches to management of risk will be covered and will include the technologies and assessment tools commonly used in behaviour change.

Respiratory failure and support:

This module will review the pathophysiology of common diseases leading to respiratory failure. It will cover the technologies used for respiratory support and airway management, methods of weaning from respiratory support and concepts related to setting up a respiratory support service. The mechanisms and management of sleep and sleep disordered breathing will also be included.

Cystic fibrosis:

In this module you will review key issues in the contemporary management of the individual with cystic fibrosis: from birth to death. This will include the complications of cystic fibrosis to other body systems, diagnostic tools (such as imaging, lung function, microbiology), personalised therapy and key issues in self-care. The module will also review the psychosocial consequences of cystic fibrosis to the patient and family. 

Our cystic fibrosis module is internationally recognised.

Pulmonary Rehabilitation AND community respiratory care:

This module will introduce you to the components of integrated respiratory care and how they contribute to the health and well-being of patients with chronic respiratory disease. You will review the evidence behind key therapies such as pulmonary rehabilitation, oxygen therapy, non-invasive ventilation and smoking cessation. You will also explore how to assess the chronic respiratory patient in the home setting particularly in the exacerbation and post-hospital discharge setting. This will include exploring the patient (and caregiver) needs and identifying specific palliative care therapies.

Quality in Cardiovascular AND respiratory healthcare delivery with E-health:

This module will cover key knowledge and skills necessary for taking a leadership role within healthcare. Technologies that facilitate the delivery of a modern and personalised healthcare service will also be discussed; such as e-health (patient held devices, fitness and well-being technologies, remote monitoring) and their impact on the delivery of quality healthcare from a patient perspective. 

Research project

This is the core requirement for the MSc course. It will involve:

  • Identifying and/or focusing on an important research question
  • Designing, planning and undertaking the project
  • Critically analysing and drawing conclusions from the data

We offer four types of project:

  • Primary research using quantitative or qualitative methods
  • Systematic review or qualitative synthesis of the literature
  • An analysis of data from research databases or registries
  • Clinical service improvement

Assessment is by written dissertation and oral presentation.

The research project can be undertaken in a variety of settings. However it will be supervised by an Imperial College London supervisor who will provide guidance and support for developing the research question, design of the project and data collection, thesis writing and oral presentation.


Genomic Medicine

Genomic modules

MSc

All Master’s students will take part in seven compulsory modules and one optional/elective module from a choice of five.  MSc students will also complete a 14 week full-time / one-year part-time research project. 

Compulsory modules

  • Core Concepts in Human Genetics and Genomics, providing all of the basic genomic science knowledge required by later modules including genomic architecture, regulatory systems, genetic variation, function and how this impacts upon disease processes and clinical outcomes. This module runs in October at the beginning of the academic year.

  • Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment (delivered by the Institute of Cancer Research) will explain the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and the ethical issues relevant to cancer. 

  • Application of Genomics in Infectious Disease will explain how pathogen genomics can inform the epidemiology of infections, impact upon drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection.

  • Omics Technologies and their Application to Genomic Medicine, providing an in-depth description of the genomic techniques that are used to assess genomic variation in clinical problems. It will allow you to critically evaluate which techniques might be used and their limitations in analysing different disease states.

  • Ethical, Legal and Social Issues in Applied Genomics will explain the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways that ethics issues are handled in various countries.  

  • Genomics of Common and Rare Inherited Diseases will explain different types of genetic variation, their contribution to rare and complex disease, how they are detected (with particular emphasis upon the 100,000 Genomes Project), interpreted and communicated. 

  • Either Bioinformatics, Quality Control, Analysis & Interpretation of Genome Sequencing Data, providing the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs) OR the less computationally intense Genomics and the Patient modulewhich will concentrate on the identification and interpretation of final Next Gen DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations.

Optional modules

  • Pharmacogenomics and Stratified Medicine will explain how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies.

  • Economic Evaluation in Human Genomics (delivered by Brunel University London) will explain the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine

  • Laboratory Skills for Genomics will be a hands-on wet lab course on how to develop a good experimental design, carry out a genomic analysis project, identify and critically analyse sequence variants and determine the implications for patients.   

  • Genome-Based Therapeutics will cover key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. 

  • Professional and Research Skills (eLearning module) will teach the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research. 

Research projects

(14 weeks full-time / one-year part-time) 

We offer four types of project:

  • laboratory-based
  • clinical-based
  • computer-based
  • literature-based

Assessment is by written dissertation, oral presentation, viva and supervisor mark.  

Research projects may be supervised at Imperial, or co-supervised at Imperial and the Institute of Cancer Research or Brunel University London. 

PG Dip

You can opt to take the seven compulsory modules, plus one optional module, to obtain a Postgraduate Diploma.

COMPULSORY MODULES

  • Core Concepts in Human Genetics and Genomics, providing all of the basic genomic science knowledge required by later modules including genomic architecture, regulatory systems, genetic variation, function and how this impacts upon disease processes and clinical outcomes. This module runs in October at the beginning of the academic year.

  • Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment (delivered by the Institute of Cancer Research) will explain the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and the ethical issues relevant to cancer. 

  • Application of Genomics in Infectious Disease will explain how pathogen genomics can inform the epidemiology of infections, impact upon drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection.

  • Omics Technologies and their Application to Genomic Medicine, providing an in-depth description of the genomic techniques that are used to assess genomic variation in clinical problems. It will allow you to critically evaluate which techniques might be used and their limitations in analysing different disease states.

  • Ethical, Legal and Social Issues in Applied Genomics will explain the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways that ethics issues are handled in various countries.  

  • Genomics of Common and Rare Inherited Diseases will explain different types of genetic variation, their contribution to rare and complex disease, how they are detected (with particular emphasis upon the 100,000 Genomes Project), interpreted and communicated. 

  • Either Bioinformatics, Quality Control, Analysis & Interpretation of Genome Sequencing Data, providing the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs) OR the less computationally intense Genomics and the Patient modulewhich will concentrate on the identification and interpretation of final Next Gen DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations.

OPTIONAL MODULES

  • Pharmacogenomics and Stratified Medicine will explain how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies.

  • Economic Evaluation in Human Genomics (delivered by Brunel University London) will explain the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine

  • Laboratory Skills for Genomics will be a hands-on wet lab course on how to develop a good experimental design, carry out a genomic analysis project, identify and critically analyse sequence variants and determine the implications for patients.   

  • Genome-Based Therapeutics will cover key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. 

  • Professional and Research Skills (eLearning module) will teach the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research. 

  • Workplace-Based Module (all distance learning) (co-delivered with Buckingham New University) will be conducted with a clinical mentor and a genomics expert. It will focus upon developing a learning contract and a proposed change in clinical practice enabled by genomic medicine approaches and the integration of new knowledge.  It will incorporate an evaluation of personal/organisational issues, the application of genomic methods to a range of cases and an evaluation of their utility. You will complete this module in your own workplace therefore it will only be available to students who work in an appropriate healthcare setting (to be approved by the module co-leads).

PG Cert

You can obtain a Postgraduate Certificate by completing four modules, which must include:

  • Core Concepts in Human Genetics and Genomics
  • At least two further compulsory modules
  • Up to one optional module

So in addition to the module on Core Concepts in Human Genetics and Genomics you might choose three other modules that are compulsory OR two compulsory and one optional module.

COMPULSORY MODULES

  • Core Concepts in Human Genetics and Genomics, providing all of the basic genomic science knowledge required by later modules including genomic architecture, regulatory systems, genetic variation, function and how this impacts upon disease processes and clinical outcomes. This module runs in October at the beginning of the academic year.

  • Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment (delivered by the Institute of Cancer Research) will explain the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and the ethical issues relevant to cancer. 

  • Application of Genomics in Infectious Disease will explain how pathogen genomics can inform the epidemiology of infections, impact upon drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection.

  • Omics Technologies and their Application to Genomic Medicine, providing an in-depth description of the genomic techniques that are used to assess genomic variation in clinical problems. It will allow you to critically evaluate which techniques might be used and their limitations in analysing different disease states.

  • Ethical, Legal and Social Issues in Applied Genomics will explain the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways that ethics issues are handled in various countries.  

  • Genomics of Common and Rare Inherited Diseases will explain different types of genetic variation, their contribution to rare and complex disease, how they are detected (with particular emphasis upon the 100,000 Genomes Project), interpreted and communicated. 

  • Either Bioinformatics, Quality Control, Analysis & Interpretation of Genome Sequencing Data, providing the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs) OR the less computationally intense Genomics and the Patient modulewhich will concentrate on the identification and interpretation of final Next Gen DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations.

 

OPTIONAL MODULES

  • Pharmacogenomics and Stratified Medicine will explain how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies.

  • Economic Evaluation in Human Genomics (delivered by Brunel University London) will explain the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine

  • Laboratory Skills for Genomics will be a hands-on wet lab course on how to develop a good experimental design, carry out a genomic analysis project, identify and critically analyse sequence variants and determine the implications for patients.   

  • Genome-Based Therapeutics will cover key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. 

  • Professional and Research Skills (eLearning module) will teach the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research. 

  • Workplace-Based Module (all distance learning) (co-delivered with Buckingham New University) will be conducted with a clinical mentor and a genomics expert. It will focus upon developing a learning contract and a proposed change in clinical practice enabled by genomic medicine approaches and the integration of new knowledge.  It will incorporate an evaluation of personal/organisational issues, the application of genomic methods to a range of cases and an evaluation of their utility. You will complete this module in your own workplace therefore it will only be available to students who work in an appropriate healthcare setting (to be approved by the module co-leads).

Short courses

Please find details of how the Genomic Medicine course modules can be taken as a short course on the Genomic Medicine short courses page.


Methods of delivery for Genomic Medicine

The teaching format will generally include:

  • Lectures: Recorded so they can be reviewed to enhance student learning. 
  • Seminars: Tutor-directed practical or discussion sessions
  • Expert Lectures: Presentations given by experts in the field of genomic medicine
  • E-learning materials and activities: Podcasts, videos, lecture notes, interactive learning tasks and discussion forums
  • Journal clubs: To assist students with the reflective aspect of their studies
  • Blackboard Learn: Virtual Learning environment which joins all teaching and learning resources together in one easy to access space
  • Laboratory sessions: some modules will include laboratory sessions, and the optional module Laboratory Skills for Genomics will be entirely laboratory based
  • Clinical visits and patient-based sessions: some modules will include clinical visits, or will invite patients into the classroom

Innovations in Clinical Cardiology

ICS structure

Core Introductory Level Modules

 Innovations in Heart Failure

Students will be introduced to the scientific and clinical basis for the aetiology, pathophysiology, diagnosis and management of heart failure. Up to date clinical trial data which have formed the basis of the National Institute of Clinical Excellence (NICE) guidelines will be analysed in detail. Lectures will be accompanied by discussion or tutorial sessions which will help to consolidate information. The module will be assessed by one piece of in course assessment and one 1.5 hour closed book examination.

Innovations in Coronary Artery Disease

Students will be introduced to the scientific principles of interventional cardiology that underpin management of patients with coronary heart disease both in acute coronary syndromes and chronic coronary heart disease. They will acquire skills in the interpretation of relevant coronary images which will be reinforced and applied in the clinical setting.  Lectures will be accompanied by tutorial/discussion sessions, workshops and observation of clinical investigations and treatment, which will help to consolidate information. The module will be assessed by one piece of in course assessment and one 1.5 hour closed book examination.

Innovations in Adult Congenital Heart Disease (ACHD)

Students will acquire the detailed knowledge of cardiac anatomy and embryology required to understand the basis of simple and complex congenital heart disease, the scientific basis for specific complications of ACHD, and its management. They will also have the opportunity to learn about the genetics and prenatal diagnosis of congenital heart disease.  The module will be assessed by one piece of in course assessment and one 1.5 hour closed book examination.

Innovations in Electrophysiology: Theory and Practice

Students will gain a thorough grounding in science of cardiac electrophysiology and will learn how to apply core principles to the management of heart rhythm.  Some teaching will be aimed at developmental and electrical pathway anatomy of the heart to reinforce and support electrophysiological principles.   State-of-the-art techniques in clinical electrophysiology will be covered and didactic teaching complemented by journal clubs, workshops and patient case-based discussions. The module will be assessed by one piece of in course assessment and one 1.5 h closed book examination.

Advanced Modules

Innovations in Heart Failure

The content of this module will build on teaching delivered in the core.  Students will learn in established multidisciplinary heart failure services and networks. Students will learn further about the research underpinning the latest clinical advances, and to critically analyse the scientific basis of more complex clinical presentations and management of heart failure. They will learn in-depth about the cutting edge investigations and treatments used in the management of heart failure, such as specialist devices and treatments such as stem cells as therapeutic agents for heart repair. The module will be assessed by two pieces of in course assessment and one 3 hour closed book examination.

Innovations in Coronary Artery Disease

The content of this module will build on teaching delivered in the core.  Students will learn about the theoretical science and advanced technologies utilised in the field of intensive percutaneous coronary interventional therapy. Then through practical workshops and tutorials, they will learn a range of techniques utilised to achieve successful interventional coronary revascularisation.  They will visit Imperial’s Department of Bioengineering where there are close collaborations on computational flow modelling, and receive tuition on various methods and technologies used to measure blood flow in humans, and gain in-depth knowledge of how imaging techniques can be applied to study coronary blood flow in humans.  The module will be assessed by two pieces of in course assessment and one 3 hour closed book examination.

iNNOVATIONS IN Adult Congenital Heart Disease (ACHD)

The content of this module will extend teaching delivered in the core.  Students will learn in-depth how to undertake specialist investigation of the underlying cause/causes of ACHD and provide specialist treatment of ACHD, including pharmacotherapy, surgical and device therapies using up-to-date evidence and guidelines. Students will spend periods of time learning in the clinical setting and in particular will focus on ACHD as a range of life-long conditions which need to be managed during normal life events such as pregnancy and also alongside co-morbidities.  Clinical exposure will provide rare opportunities to integrate and apply knowledge relating to a number of ACHD. The module will be assessed by two pieces of in course assessment and one 3 hour closed book examination.

Innovations in Electrophysiology: Theory and Practice

The content of this module will build on teaching delivered in the relevant core. This module will comprehensively cover the current knowledge of more intensive electrophysiological rhythm management.  Students will learn further about the research underpinning the latest clinical advances, and to critically analyse the scientific basis of more complex clinical presentations and management of arrhythmias.  Practical sessions in the simulator electrophysiology lab will teach advanced electrophysiological techniques, and demonstration sessions will allow students to see anatomical specimens of cardiac anatomy that is visualized when using advanced imaging techniques, and targeted when treating arrhythmias in the electrophysiology lab.  The module will be assessed by two pieces of in course assessment and one 3 hour closed book examination.

Stream Specific Research Project

Stream Specific Research Projects                                         

Each MSc student will undertake a 6 month original research project in their chosen specialist stream.  Projects may be laboratory, clinical or library based. Students will join an established team of academic and clinical staff to conduct their projects. On completion of the project, students will produce a 10,000 word report and give an oral presentation.