Imperial College London

ProfessorAlessandroAstolfi

Faculty of EngineeringDepartment of Electrical and Electronic Engineering

College Consul for Faculty of Engineering & Business School
 
 
 
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Contact

 

+44 (0)20 7594 6289a.astolfi Website

 
 
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Assistant

 

Mrs Raluca Reynolds +44 (0)20 7594 6281

 
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Location

 

1112Electrical EngineeringSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Chang:2016:10.1049/iet-syb.2016.0008,
author = {Chang, H and Moog, C and Astolfi, A},
doi = {10.1049/iet-syb.2016.0008},
journal = {IET Systems Biology},
pages = {237--243},
title = {Occurrence of HIV eradication for preexposure prophylaxis treatment with a deterministic HIV model},
url = {http://dx.doi.org/10.1049/iet-syb.2016.0008},
volume = {10},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The authors examine the human immunodeficiency virus (HIV) eradication in this study using a mathematical model and analyse the occurrence of virus eradication during the early stage of infection. To this end they use a deterministic HIV-infection model, modify it to describe the pharmacological dynamics of antiretroviral HIV drugs, and consider the clinical experimental results of preexposure prophylaxis HIV treatment. They also use numerical simulation to model the experimental scenario, thereby supporting the clinical results with a model-based explanation. The study results indicate that the protocol employed in the experiment can eradicate HIV in infected patients at the early stage of the infection.
AU - Chang,H
AU - Moog,C
AU - Astolfi,A
DO - 10.1049/iet-syb.2016.0008
EP - 243
PY - 2016///
SN - 1751-8857
SP - 237
TI - Occurrence of HIV eradication for preexposure prophylaxis treatment with a deterministic HIV model
T2 - IET Systems Biology
UR - http://dx.doi.org/10.1049/iet-syb.2016.0008
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000389473600005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - http://hdl.handle.net/10044/1/44456
VL - 10
ER -