My research, with Professor Austin Burt, is on reaction-diffusion models of population dynamics and on spatial and temporal evolution and propagation of invading population waveforms. The primary focus is on modelling the usage of selfish genetic elements to genetically manipulate natural populations of mosquitoes that transmit malaria.
et al., 2020, A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae, Nature Biotechnology, Vol:38, ISSN:1087-0156, Pages:1054-1060
et al., 2019, Gene drive for population genetic control: non-functional resistance and parental effects, Proceedings of the Royal Society B: Biological Sciences, Vol:286, ISSN:0962-8452, Pages:1-8
et al., 2019, Integral Gene Drives for population replacement, Biology Open, Vol:8, ISSN:2046-6390
et al., 2018, A CRISPR-Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes, Nature Biotechnology, Vol:36, ISSN:1087-0156, Pages:1062-1066
Beaghton AK, Beaghton PJ, Burt A, 2017, Vector control with driving Y chromosomes: modelling the evolution of resistance, Malaria Journal, Vol:16, ISSN:1475-2875
et al., 2017, Requirements for Driving Antipathogen Effector Genes into Populations of Disease Vectors by Homing, Genetics, Vol:205, Pages:1587-1596
Beaghton A, Beaghton PJ, Burt A, 2016, Gene drive through a landscape: Reaction–diffusion models of population suppression and elimination by a sex ratio distorter, Theoretical Population Biology, Vol:108, ISSN:1096-0325, Pages:51-69