Imperial College London

Professor Aldo R. Boccaccini

Faculty of EngineeringDepartment of Materials

Visiting Professor



+44 (0)20 7594 6731a.boccaccini




210Royal School of MinesSouth Kensington Campus






BibTex format

author = {Lizarraga-Valderrama, LR and Panchal, B and Thomas, C and Boccaccini, AR and Roy, I},
booktitle = {Biomaterials from Nature for Advanced Devices and Therapies},
doi = {10.1002/9781119126218.ch20},
pages = {337--383},
title = {Biomedical Applications of Polyhydroxyalkanoates},
url = {},
year = {2016}

RIS format (EndNote, RefMan)

AB - © 2016 by John Wiley & Sons, Inc. All rights reserved. Polyhydroxyalkanoates (PHAs) are a family of linear polyesters consisting of 3,4, 5 and 6-hydroxyacids, synthesized by a variety of bacterial species. PHAs are divided into two groups based on the number of carbon atoms in their monomer units; short-chain-length (scl) PHAs and medium-chain-length (mcl) PHAs. Biodegradability is an essential material property required for tissue engineering and drug delivery applications. Various methods of manufacture can be used to alter the biodegradability of PHA devices such as by blending with others polymers, increasing the porosity and increasing the exposed surface area. PHAs have also been demonstrated to be suitable for use as scaffolds in tissue engineering since they are easily degradable and favor proliferation and attachment of cells. In the field of skin tissue engineering research, various skin components, cytokines, growth factors, and transcription factors have been used experimentally. Melanocytes have been seeded on various polymer scaffolds, as well as sweat and sebaceous glands.
AU - Lizarraga-Valderrama,LR
AU - Panchal,B
AU - Thomas,C
AU - Boccaccini,AR
AU - Roy,I
DO - 10.1002/9781119126218.ch20
EP - 383
PY - 2016///
SN - 9781118478059
SP - 337
TI - Biomedical Applications of Polyhydroxyalkanoates
T1 - Biomaterials from Nature for Advanced Devices and Therapies
UR -
ER -