Imperial College London

Professor Aldo R. Boccaccini

Faculty of EngineeringDepartment of Materials

Visiting Professor
 
 
 
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Contact

 

+44 (0)20 7594 6731a.boccaccini

 
 
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Location

 

210Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

1188 results found

Araujo M, Viveiros R, Philippart A, Miola M, Doumett S, Baldi G, Perez J, Boccaccini AR, Aguiar-Ricardo A, Verne Eet al., 2017, Bioactivity, mechanical properties and drug delivery ability of bioactive glass-ceramic scaffolds coated with a natural-derived polymer, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, Vol: 77, Pages: 342-351, ISSN: 0928-4931

JOURNAL ARTICLE

Balasubramanian P, Hupa L, Jokic B, Detsch R, Grunewald A, Boccaccini ARet al., 2017, Angiogenic potential of boron-containing bioactive glasses: in vitro study, JOURNAL OF MATERIALS SCIENCE, Vol: 52, Pages: 8785-8792, ISSN: 0022-2461

JOURNAL ARTICLE

Bejarano J, Detsch R, Boccaccini AR, Palza Het al., 2017, PDLLA scaffolds with Cu- and Zn-doped bioactive glasses having multifunctional properties for bone regeneration, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol: 105, Pages: 746-756, ISSN: 1549-3296

JOURNAL ARTICLE

Bertolla L, Dlouhy I, Tatarko P, Viani A, Mahajan A, Chlup Z, Reece MJ, Boccaccini ARet al., 2017, Pressureless spark plasma-sintered Bioglass (R) 45S5 with enhanced mechanical properties and stress-induced new phase formation, JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, Vol: 37, Pages: 2727-2736, ISSN: 0955-2219

JOURNAL ARTICLE

Boccaccini AR, 2017, Editorial Note, MATERIALS LETTERS, Vol: 197, Pages: 249-249, ISSN: 0167-577X

JOURNAL ARTICLE

Boccaccini AR, Brauer DS, Hupa L, 2017, Preface

BOOK

Boccaccini AR, Fenn M, Jones JR, Kasuga T, Norton MG, Rahaman MN, Verne E, Zanotto EDet al., 2017, Guest editors' preface, JOURNAL OF MATERIALS SCIENCE, Vol: 52, Pages: 8691-8694, ISSN: 0022-2461

JOURNAL ARTICLE

Boccaccini AR, Willoughby A, 2017, The 35th anniversary of Materials Letters, Materials Letters, Vol: 208, Pages: 1-2, ISSN: 0167-577X

JOURNAL ARTICLE

Boccardi E, Ciraldo FE, Boccaccini AR, 2017, Bioactive glass-ceramic scaffolds: Processing and properties, MRS BULLETIN, Vol: 42, Pages: 226-232, ISSN: 0883-7694

JOURNAL ARTICLE

Cordero-Arias L, Boccaccini AR, 2017, Electrophoretic deposition of chondroitin sulfate-chitosan/bioactive glass composite coatings with multilayer design, SURFACE & COATINGS TECHNOLOGY, Vol: 315, Pages: 417-425, ISSN: 0257-8972

JOURNAL ARTICLE

Demir M, Ramos-Rivera L, Silva R, Nazhat SN, Boccaccini ARet al., 2017, Zein-based composites in biomedical applications, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol: 105, Pages: 1656-1665, ISSN: 1549-3296

JOURNAL ARTICLE

Dippold D, Cai A, Hardt M, Boccaccini AR, Horch R, Beier JP, Schubert DWet al., 2017, Novel approach towards aligned PCL-Collagen nanofibrous constructs from a benign solvent system, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, Vol: 72, Pages: 278-283, ISSN: 0928-4931

JOURNAL ARTICLE

Ege D, Duru I, Kamali AR, Boccaccini ARet al., 2017, Nitride, Zirconia, Alumina, and Carbide Coatings on Ti6Al4V Femoral Heads: Effect of Deposition Techniques on Mechanical and Tribological Properties, Advanced Engineering Materials, ISSN: 1438-1656

© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Ti6Al4V has been extensively studied in orthopedic applications because of its biocompatibility, desirable mechanical strength, and fatigue resistance. A wide range of bioinert ceramics have been investigated to further develop the tribological and mechanical properties of Ti6Al4V for the production of potential femoral heads. However, an analysis of the literature indicates that the performance of the coatings produced has been inconsistent. In this review, for the first-time deposition techniques of the most widely studied bioinert ceramics namely nitrides, carbides, zirconia, and alumina on Ti6Al4V substrates and their relevant mechanical and tribological performance have been analyzed. Finally, graphene has also been suggested for use together with bioinert ceramics due to its excellent mechanical and physical properties for coating Ti6Al4V femoral heads.

JOURNAL ARTICLE

Fiocco L, Elsayed H, Badocco D, Pastore P, Bellucci D, Cannillo V, Detsch R, Boccaccini AR, Bernardo Eet al., 2017, Direct ink writing of silica-bonded calcite scaffolds from preceramic polymers and fillers., Biofabrication, Vol: 9

Silica-bonded calcite scaffolds have been successfully 3D-printed by direct ink writing, starting from a paste comprising a silicone polymer and calcite powders, calibrated in order to match a SiO2/CaCO3 weight balance of 35/65. The scaffolds, fabricated with two slightly different geometries, were first cross-linked at 350 °C, then fired at 600 °C, in air. The low temperature adopted for the conversion of the polymer into amorphous silica, by thermo-oxidative decomposition, prevented the decomposition of calcite. The obtained silica-bonded calcite scaffolds featured open porosity of about 56%-64% and compressive strength of about 2.9-5.5 MPa, depending on the geometry. Dissolution studies in SBF and preliminary cell culture tests, with bone marrow stromal cells, confirmed the in vitro bioactivity of the scaffolds and their biocompatibility. The seeded cells were found to be alive, well anchored and spread on the samples surface. The new silica-calcite composites are expected to be suitable candidates as tissue-engineering 3D scaffolds for regeneration of cancellous bone defects.

JOURNAL ARTICLE

Frank MA, Meltzer C, Braunschweig B, Peukert W, Boccaccini AR, Virtanen Set al., 2017, Functionalization of steel surfaces with organic acids: Influence on wetting and corrosion behavior, APPLIED SURFACE SCIENCE, Vol: 404, Pages: 326-333, ISSN: 0169-4332

JOURNAL ARTICLE

Galarraga-Vinueza ME, Mesquita-Guimaraes J, Magini RS, Souza JCM, Fredel MC, Boccaccini ARet al., 2017, Anti-biofilm properties of bioactive glasses embedding organic active compounds, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol: 105, Pages: 672-679, ISSN: 1549-3296

JOURNAL ARTICLE

Germaini M-M, Detsch R, Gruenewald A, Magnaudeix A, Lalloue F, Boccaccini AR, Champion Eet al., 2017, Osteoblast and osteoclast responses to A/B type carbonate-substituted hydroxyapatite ceramics for bone regeneration, BIOMEDICAL MATERIALS, Vol: 12, ISSN: 1748-6041

JOURNAL ARTICLE

Haro Durand LA, Vargas GE, Vera-Mesones R, Baldi A, Zago MP, Fanovich MA, Boccaccini AR, Gorustovich Aet al., 2017, In Vitro Human Umbilical Vein Endothelial Cells Response to Ionic Dissolution Products from Lithium-Containing 45S5 Bioactive Glass, MATERIALS, Vol: 10, ISSN: 1996-1944

JOURNAL ARTICLE

Heise S, Hoehlinger M, Torres Hernandez Y, Pavon Palacio JJ, Rodriquez Ortiz JA, Wagener V, Virtanen S, Boccaccini ARet al., 2017, Electrophoretic deposition and characterization of chitosan/bioactive glass composite coatings on Mg alloy substrates, ELECTROCHIMICA ACTA, Vol: 232, Pages: 456-464, ISSN: 0013-4686

JOURNAL ARTICLE

Hochleitner G, Kessler M, Schmitz M, Boccaccini AR, Tessmar J, Groll Jet al., 2017, Melt electrospinning writing of defined scaffolds using polylactide-poly (ethylene glycol) blends with 45S5 bioactive glass particles, MATERIALS LETTERS, Vol: 205, Pages: 257-260, ISSN: 0167-577X

JOURNAL ARTICLE

Hoehlinger M, Heise S, Wagener V, Boccaccini AR, Virtanen Set al., 2017, Developing surface pre-treatments for electrophoretic deposition of biofunctional chitosan-bioactive glass coatings on a WE43 magnesium alloy, APPLIED SURFACE SCIENCE, Vol: 405, Pages: 441-448, ISSN: 0169-4332

JOURNAL ARTICLE

Hoppe A, Boccaccini AR, 2017, Chapter 16: Bioactive Glasses as Carriers of Therapeutic Ions and the Biological Implications, RSC Smart Materials, Pages: 362-392

© The Royal Society of Chemistry 2017. In the last few decades bioactive glasses (BGs) have been widely considered for bone tissue engineering applications due to their bioactivity and their osteogenic effects. The available scientific evidence suggests that ionic dissolution products (at a critical concentration) released during the degradation of the BG matrix induce osteogenic gene expression hence stimulating the bone regeneration process. Moreover, adding bioactive metallic ions (e.g. boron, copper, cobalt, lithium silver, zinc and strontium) to silicate as well as to phosphate and borate glasses has emerged as a promising route to develop novel BG formulations with specific therapeutic functionalities, including antibacterial, angiogenic, osteogenic and wound healing. The degradation behaviour of BGs can be tailored by adjusting the glass chemistry, making these biomaterials suitable carrier systems for controlled therapeutic ion release. This book chapter summarizes the fundamental aspects of the effect of ionic dissolution products released from BGs on osteogenesis and angiogenesis, also discussing novel BG compositions containing inorganic therapeutic agents. In vitro cellular as well as in vivo responses to specific therapeutic ions are discussed.

BOOK CHAPTER

Juhasz-Bortuzzo JA, Myszka B, Silva R, Boccaccini ARet al., 2017, Sonosynthesis of Vaterite-Type Calcium Carbonate, CRYSTAL GROWTH & DESIGN, Vol: 17, Pages: 2351-2356, ISSN: 1528-7483

JOURNAL ARTICLE

Karbowniczek J, Cordero-Arias L, Virtanen S, Misra SK, Valsami-Jones E, Tuchscherr L, Rutkowski B, Gorecki K, Bala P, Czyrska-Filemonowicz A, Boccaccini ARet al., 2017, Electrophoretic deposition of organic/inorganic composite coatings containing ZnO nanoparticles exhibiting antibacterial properties, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, Vol: 77, Pages: 780-789, ISSN: 0928-4931

JOURNAL ARTICLE

Kaya S, Boccaccini AR, 2017, Electrophoretic deposition of zein coatings, JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH, Vol: 14, Pages: 683-689, ISSN: 1945-9645

JOURNAL ARTICLE

Macias-Andres VI, Li W, Aguilar-Reyes EA, Ding Y, Roether JA, Harhaus L, Leon-Patino CA, Boccaccini ARet al., 2017, Preparation and characterization of 45S5 bioactive glass-based scaffolds loaded with PHBV microspheres with daidzein release function, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol: 105, Pages: 1765-1774, ISSN: 1549-3296

JOURNAL ARTICLE

Meincke T, Pacheco VM, Hoffmann D, Boccaccini AR, Taylor RNKet al., 2017, Engineering the surface functionality of 45S5 bioactive glass-based scaffolds by the heterogeneous nucleation and growth of silver particles, JOURNAL OF MATERIALS SCIENCE, Vol: 52, Pages: 9082-9090, ISSN: 0022-2461

JOURNAL ARTICLE

Mesquita-Guimaraes J, Leite MA, Souza JCM, Henriques B, Silva FS, Hotza D, Boccaccini AR, Fredel MCet al., 2017, Processing and strengthening of 58S bioactive glass-infiltrated titania scaffolds, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol: 105, Pages: 590-600, ISSN: 1549-3296

JOURNAL ARTICLE

Miguez-Pacheco V, Gorustovich AA, Boccaccini AR, Roether JAet al., 2017, Chapter 15: Bioactive Glasses for Soft Tissue Engineering Applications, RSC Smart Materials, Pages: 336-361

© The Royal Society of Chemistry 2017. In the last few years the usage of bioactive glasses as scaffolds for soft tissue engineering has been investigated more thoroughly. The reason for the boost in interest is the attractive properties bioactive glasses offer, including bioactivity as well as antibacterial, angiogenic and hemostatic properties. So far, most research efforts have focused on applications for repairing skin and nerve tissue although there have been interesting developments in other fields including lung and intestine, which could potentially benefit a large group of patients. Three review articles on this topic have been published, so this chapter will mainly focus on the latest relevant findings. A great number of patents have been registered for the use of bioactive glass for hard tissue engineering. Recently, however, patents have been filed detailing the use of bioactive glass for soft tissue engineering applications which open the way to marketing bioactive glasses for soft tissue repair. The angiogenic effect of bioactive glasses and their dissolution products is of great interest for tissue engineering applications in general and in particular for soft tissue regeneration and repair. The third part of this chapter will detail the latest research on these angiogenic properties of bioactive glasses.

BOOK CHAPTER

Molin S, Sabato AG, Bindi M, Leone P, Cempura G, Salvo M, Cabanas Polo S, Boccaccini AR, Smeacetto Fet al., 2017, Microstructural and electrical characterization of Mn-Co spinel protective coatings for solid oxide cell interconnects, Journal of the European Ceramic Society, Vol: 37, Pages: 4781-4791, ISSN: 0955-2219

© 2017 Elsevier Ltd Electrophoretic deposition, thermal co-evaporation and RF magnetron sputtering methods are used for the preparation of Mn-Co based ceramic coatings for solid oxide fuel cell steel interconnects. Both thin and relatively thick coatings (1–15 μm) are prepared and characterised for their potential protective behaviour. Mn-Co coated Crofer22APU samples are electrically tested for 5000 h at 800 °C under a 500 mA cm −2 current load to determine their Area Specific Resistance increase due to a growing chromia scale. After tests, samples are analysed by scanning and transmission electron microscopy. Analysis is focused on the potential chromium diffusion to or through the coating, the oxide scale thickness and possible reactions at the interfaces. The relationships between the coating type, thickness and effectiveness are reviewed and discussed. Out of the three Mn-Co coatings compared in this study, the one deposited by electrophoretic deposition presents the best protection against Cr diffusion and offers long term stability.

JOURNAL ARTICLE

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