Imperial College London

ProfessorAnneBowcock

Faculty of MedicineNational Heart & Lung Institute

Visiting Professor
 
 
 
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Contact

 

+44 (0)20 7594 1511a.bowcock

 
 
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Location

 

Guy Scadding BuildingRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Bowcock:1988,
author = {Bowcock, AM and Fahnestock, M and Goslin, K and Shooter, EM},
journal = {Brain Res},
pages = {165--172},
title = {The NGF and kallikrein genes of mouse, the African rat Mastomys natalensis and man: their distribution and mode of expression in the salivary gland.},
url = {https://www.ncbi.nlm.nih.gov/pubmed/3133079},
volume = {427},
year = {1988}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The kallikrein genes and their expression in the salivary glands of mouse, the African rat Mastomys natalensis and human were compared. The Mastomys kallikrein genes comprise a family of genes similar to those of mouse. Androgen markedly enhances transcription of glandular nerve growth factor (NGF) and kallikrein in both male and female Mastomys suggesting the presence of testosterone regulated kallikrein genes for growth factor precursor-processing in both sexes. In contrast, although a kallikrein transcript was detected in human salivary glands of the same size as the mouse or Mastomys transcript no difference in the amount of transcript was seen in adult male or female. The absence of kallikrein genes regulated by testosterone and of NGF transcripts in the human implies that there is no human equivalent of the mouse salivary 7S NGF complex.
AU - Bowcock,AM
AU - Fahnestock,M
AU - Goslin,K
AU - Shooter,EM
EP - 172
PY - 1988///
SN - 0006-8993
SP - 165
TI - The NGF and kallikrein genes of mouse, the African rat Mastomys natalensis and man: their distribution and mode of expression in the salivary gland.
T2 - Brain Res
UR - https://www.ncbi.nlm.nih.gov/pubmed/3133079
VL - 427
ER -