Imperial College London

Dr Abigail Clements

Faculty of Natural SciencesDepartment of Life Sciences

Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 7681a.clements

 
 
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Location

 

Lvl 1Flowers buildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Clements:2012:10.4161/gmic.19182,
author = {Clements, A and Young, JC and Constantinou, N and Frankel, G},
doi = {10.4161/gmic.19182},
journal = {Gut Microbes},
pages = {71--87},
title = {Infection strategies of enteric pathogenic Escherichia coli.},
url = {http://dx.doi.org/10.4161/gmic.19182},
volume = {3},
year = {2012}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Enteric Escherichia coli (E. coli) are both natural flora of humans and important pathogens causing significant morbidity and mortality worldwide. Traditionally enteric E. coli have been divided into 6 pathotypes, with further pathotypes often proposed. In this review we suggest expansion of the enteric E. coli into 8 pathotypes to include the emerging pathotypes of adherent invasive E. coli (AIEC) and Shiga-toxin producing enteroaggregative E. coli (STEAEC). The molecular mechanisms that allow enteric E. coli to colonize and cause disease in the human host are examined and for two of the pathotypes that express a type 3 secretion system (T3SS) we discuss the complex interplay between translocated effectors and manipulation of host cell signaling pathways that occurs during infection.
AU - Clements,A
AU - Young,JC
AU - Constantinou,N
AU - Frankel,G
DO - 10.4161/gmic.19182
EP - 87
PY - 2012///
SP - 71
TI - Infection strategies of enteric pathogenic Escherichia coli.
T2 - Gut Microbes
UR - http://dx.doi.org/10.4161/gmic.19182
UR - https://www.ncbi.nlm.nih.gov/pubmed/22555463
VL - 3
ER -