Publications
2252 results found
Unadkat SN, Leff DR, Teoh T-G, et al., 2010, Anorectal symptoms during pregnancy: how important is trimester?, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, Vol: 25, Pages: 375-379, ISSN: 0179-1958
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- Citations: 4
Arora S, Sevdalis N, Nestel D, et al., 2010, The impact of stress on surgical performance: A systematic review of the literature, SURGERY, Vol: 147, Pages: 318-330, ISSN: 0039-6060
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- Citations: 379
Gogalniceanu P, Sheena Y, Kashef E, et al., 2010, Is Basic Emergency Ultrasound Training Feasible as Part of Standard Undergraduate Medical Education?, JOURNAL OF SURGICAL EDUCATION, Vol: 67, Pages: 152-156, ISSN: 1931-7204
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- Citations: 106
Chow A, Aziz O, Purkayastha S, et al., 2010, Single incision laparoscopic surgery for acute appendicitis: feasibility in pediatric patients, Diagnostic and Therapeutic Endoscopy, Vol: 2010, ISSN: 1070-3608
Background. Laparoscopic appendicectomy is accepted by many as the gold standard approach for the treatment of acute appendicitis. The use of Single Incision Laparoscopic Surgery (SILS) has the potential of further reducing postoperative port site complications as well as improving cosmesis and patient satisfaction. Method. In this paper we report our experience and assess the feasibility of SILS appendicectomy in the pediatric setting. Results. Five pediatric patients with uncomplicated appendicitis underwent SILS appendicectomy. There were no significant intraoperative or postoperative complications. All patients were discharged within 24 hours. Conclusions. The use of Single Incision Laparoscopic Surgery appears to be a feasible and safe technique for the treatment of uncomplicated appendicitis in the pediatric setting. Further studies are warranted to fully investigate the potential advantages of this new technique.
Kinross J, Darzi A, 2010, Key Topics in Surgical Research and Methodology, Key Topics in Surgical Research and Methodology, Editors: Athanasiou, Darzi, Publisher: Springer Verlag, ISBN: 9783540719144
An Introduction to Animal Research James Kinross and Lord .... An understanding of the principals of animal research therefore remains a necessity for ...
Jarral OA, Purkayastha S, Darzi A, et al., 2010, Gastrointestinal: Enterolith-induced perforation on a background of jejunal diverticulum, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Vol: 25, Pages: 429-429, ISSN: 0815-9319
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- Citations: 1
Sugden C, Darzi A, 2010, The performance effects of sleep deprivation and fatigue, SURGERY, Vol: 147, Pages: 255-256, ISSN: 0039-6060
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- Citations: 2
Saso S, James D, Vecht JA, et al., 2010, Effect of Skeletonization of the Internal Thoracic Artery for Coronary Revascularization on the Incidence of Sternal Wound Infection, ANNALS OF THORACIC SURGERY, Vol: 89, Pages: 661-670, ISSN: 0003-4975
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- Citations: 61
Jones CM, Ashrafian H, Darzi A, et al., 2010, Guidelines for Diagnostic Tests and Diagnostic Accuracy in Surgical Research, JOURNAL OF INVESTIGATIVE SURGERY, Vol: 23, Pages: 57-65, ISSN: 0894-1939
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- Citations: 21
Saso S, Vecht JA, Rao C, et al., 2010, Statin therapy may influence the incidence of postoperative atrial fibrillation: what is the evidence?, Texas Heart Institute Journal, Vol: 36, Pages: 521-529, ISSN: 1526-6702
Atrial fibrillation is the most common postoperative arrhythmia in patients who undergo cardiac surgery. We sought to determine whether the administration of statins reduces the incidence of postoperative atrial fibrillation in cardiac surgery patients. We performed a meta-analysis on all studies published between 2004 and 2008 that reported comparisons between statin treatment or nontreatment in these patients. Our primary focus was the incidence of postoperative atrial fibrillation. Random-effects modeling and sensitivity analysis were used to evaluate the consistency of the calculated treatment effect. Ten qualifying studies generated a total of 4,459 patients. The incidence of postoperative atrial fibrillation was 22.6% (622/2,758) in the statin-treated group and 29.8% (507/1,701) in the untreated group. Using the random-effects model, we calculated an odds ratio (OR) of 0.60 (95% confidence interval [CI], 0.48-0.76). When we considered only the 4 randomized studies (919 patients) in order to reduce the effects of heterogeneity, this significant reduction in the incidence of postoperative atrial fibrillation in the statin group was maintained (OR, 0.55; 95% CI, 0.41-0.73) with no heterogeneity (chi2 of heterogeneity, 2.96; P = 0.4). In studies wherein only coronary artery bypass grafting was performed, statin treatment decreased postoperative atrial fibrillation (OR, 0.64; 95% CI, 0.43-0.95). We conclude that statin administration results in a reduction in the incidence of atrial fibrillation in patients who undergo cardiac surgery. Further research into the underlying mechanism can elucidate possible relationships between the dosage and type of statin used.
Vats A, Vincent CA, Nagpal K, et al., 2010, Practical challenges of introducing WHO surgical checklist: UK pilot experience, BRITISH MEDICAL JOURNAL, Vol: 340, ISSN: 0959-535X
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- Citations: 156
Ahmed K, Keeling AN, Fakhry M, et al., 2010, Role of Virtual Reality Simulation in Teaching and Assessing Technical Skills in Endovascular Intervention, J Vasc Interv Radiol, Vol: 21
Nagpal K, Ahmed K, Vats A, et al., 2010, Is minimally invasive surgery beneficial in the management of esophageal cancer? A meta-analysis, Surg Endosc
INTRODUCTION: Open esophagectomy for cancer is a major oncological procedure, associated with significant morbidity and mortality. Recently, thoracoscopic procedures have offered a potentially advantageous alternative because of less operative trauma compared with thoracotomy. The aim of this study was to utilize meta-analysis to compare outcomes of open esophagectomy with those of minimally invasive esophagectomy (MIE) and hybrid minimally invasive esophagectomy (HMIE). METHODS: Literature search was performed using Medline, Embase, Cochrane Library, and Google Scholar databases for comparative studies assessing different techniques of esophagectomy. A random-effects model was used for meta-analysis, and heterogeneity was assessed. Primary outcomes of interest were 30-day mortality and anastomotic leak. Secondary outcomes included operative outcomes, other postoperative outcomes, and oncological outcomes in terms of lymph nodes retrieved. RESULTS: A total of 12 studies were included in the analysis. Studies included a total of 672 patients for MIE and HMIE, and 612 for open esophagectomy. There was no significant difference in 30-day mortality; however, MIE had lower blood loss, shorter hospital stay, and reduced total morbidity and respiratory complications. For all other outcomes, there was no significant difference between the two groups. CONCLUSION: Minimally invasive esophagectomy is a safe alternative to the open technique. Patients undergoing MIE may benefit from shorter hospital stay, and lower respiratory complications and total morbidity compared with open esophagectomy. Multicenter, prospective large randomized controlled trials are required to confirm these findings in order to base practice on sound clinical evidence.
Arora S, Hull L, Sevdalis N, et al., 2010, Factors compromising safety in surgery: stressful events in the operating room, AMERICAN JOURNAL OF SURGERY, Vol: 199, Pages: 60-65, ISSN: 0002-9610
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- Citations: 117
Arora S, Aggarwal R, Sevdalis N, et al., 2010, Development and validation of mental practice as a training strategy for laparoscopic surgery, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol: 24, Pages: 179-187, ISSN: 0930-2794
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- Citations: 70
James DRC, Orihuela-Espina F, Leff DR, et al., 2010, Cognitive Burden Estimation for Visuomotor Learning with fNIRS, 13th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), Publisher: SPRINGER-VERLAG BERLIN, Pages: 319-326, ISSN: 0302-9743
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- Citations: 17
Kneebone R, Arora S, King D, et al., 2010, Distributed simulation - Accessible immersive training, MEDICAL TEACHER, Vol: 32, Pages: 65-70, ISSN: 0142-159X
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- Citations: 84
Aggarwal R, Darzi LA, 2010, Measurement of Surgical Performance for Delivery of a Competency-Based Training Curriculum, KEY TOPICS IN SURGICAL RESEARCH AND METHODOLOGY, Editors: Athanasiou, Debas, Darzi, Publisher: SPRINGER-VERLAG BERLIN, Pages: 115-127, ISBN: 978-3-540-71914-4
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- Citations: 1
Leff DR, Lovegrove RE, Darzi LA, et al., 2010, Data Collection, Database Development and Quality Control: Guidance for Clinical Research Studies, KEY TOPICS IN SURGICAL RESEARCH AND METHODOLOGY, Editors: Athanasiou, Debas, Darzi, Publisher: SPRINGER-VERLAG BERLIN, Pages: 305-320, ISBN: 978-3-540-71914-4
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- Citations: 1
Chow A, Mayer E, Darzi LA, et al., 2010, Patient Satisfaction in Surgery, KEY TOPICS IN SURGICAL RESEARCH AND METHODOLOGY, Pages: 165-173
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- Citations: 1
Mayer E, Chow A, Darzi LA, et al., 2010, How can we Assess Quality of Care in Surgery?, KEY TOPICS IN SURGICAL RESEARCH AND METHODOLOGY, Pages: 151-164
Mayer E, Darzi LA, Athanasiou T, 2010, The Role of Volume-Outcome Relationship in Surgery, KEY TOPICS IN SURGICAL RESEARCH AND METHODOLOGY, Pages: 195-206
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- Citations: 2
Athanasiou T, Debas HT, Darzi A, 2010, Key Topics in Surgical Research and Methodology, Publisher: Springer, ISBN: 9783540719151
Key Topics in Surgical Research and Methodology represents a comprehensive reference text accessible to the surgeon embarking on an academic career. Key themes emphasize and summarize the text. Four key elements are covered, i.e.
Patel V, Aggarwal R, Osinibi E, et al., 2010, Operating theatre (OT) introduction for the novice student, Electronic Poster of Distinction in Association-of-Surgeons-of-Great-Britain-and-Ireland-International-Surgical-Congress, Publisher: WILEY-BLACKWELL, Pages: 118-118, ISSN: 0007-1323
Noonan DP, Payne CJ, Shang J, et al., 2010, Force adaptive multi-spectral imaging with an articulated robotic endoscope, Med Image Comput Comput Assist Interv, Vol: 13, Pages: 245-252
Recent developments in optical spectroscopic techniques have permitted in vivo, in situ cellular and molecular sensing and imaging to allow for real-time tissue characterization, functional assessment, and intraoperative guidance. The small area sensed by these probes, however, presents unique challenges when attempting to obtain useful tissue information in-vivo due to the need to maintain constant distance or contact with the target, and tissue deformation. In practice, the effective area can be increased by translating the tip of the probe over the tissue surface and generating functional maps of the underlying tissue response. However, achieving such controlled motions under manual guidance is very difficult, particularly since the probe is typically passed down the instrument channel of a flexible endoscope. This paper describes a force adaptive multi-spectral imaging system integrated with an articulated robotic endoscope that allows a constant contact force to be maintained between the probe and the tissue as the robot tip is actuated across complex tissue profiles. Detailed phantom and ex-vivo tissue validation is provided.
King D, Lee H, Darzi A, 2010, Abandoned HealthSpace: Smart phones may help, British Medical Journal
Cohen D, Mayer E, Chen D, et al., 2010, Augmented Reality Image Guidance in Minimally Invasive Prostatectomy, International Workshop on Prostate Cancer Imaging, Publisher: SPRINGER-VERLAG BERLIN, Pages: 101-+, ISSN: 0302-9743
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- Citations: 21
Paggetti G, Menegaz G, Leff DR, et al., 2010, Exploring the link between depth perception, hand eye coordination and parietal lobe activation during robotic-assisted interventions, PERCEPTION, Vol: 39, Pages: 162-163, ISSN: 0301-0066
King D, Peach G, Lee H, et al., 2010, Preventability of adverse events and critical incidents of patients undergoing surgery for colorectal cancer and subsequent outcome, Electronic Poster of Distinction in Association-of-Surgeons-of-Great-Britain-and-Ireland-International-Surgical-Congress, Publisher: WILEY-BLACKWELL, Pages: 151-151, ISSN: 0007-1323
Almoudaris A, Burns E, Bottle A, et al., 2010, Do surgical units that submit data to a voluntary national colorectal cancer registry have better outcomes than those that do not?, Electronic Poster of Distinction in Association-of-Surgeons-of-Great-Britain-and-Ireland-International-Surgical-Congress, Publisher: WILEY-BLACKWELL, Pages: 43-43, ISSN: 0007-1323
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