Publications
2252 results found
Faraci A, Bello F, Darzi A, 2004, Soft tissue deformation using a hierarchical finite element model, MEDICINE MEETS VIRTUAL REALITY 12, Vol: 98, Pages: 92-98, ISSN: 0926-9630
Dosis A, Bello F, Moorthy K, et al., 2004, Real-time synchronization of kinematic and video data for the comprehensive assessment of surgical skills, MEDICINE MEETS VIRTUAL REALITY 12, Vol: 98, Pages: 82-88, ISSN: 0926-9630
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- Citations: 13
Aziz O, Panesar S, Paraskeva P, et al., 2004, Improving hospital communication: do mobile phone networks hold the key?, Int J Surg, Vol: 2, Pages: 125-126
ElHelw MA, Lo BP, Darzi A, et al., 2004, Real-time photo-realistic rendering for surgical simulations with graphics hardware, Berlin, 2nd international workshop on medical imaging and augmented reality (MIAR 2004), Beijing, Peoples R China, Publisher: Springer-Verlag, Pages: 346-352
Purkayastha S, Aziz O, Athanasiou T, et al., 2004, Does laparoscopic surgery offer adequate clearance for rectal cancer? – a discussion., International Journal of Surgery, Vol: 2
ElHelw MA, Lo BP, Chung AJ, et al., 2004, Photorealistic rendering of large tissue deformation for surgical simulation, Berlin, 7th international conference on medical image computing and computer - assisted intervention (MICCAI 2004), St Malo, France, Publisher: Springer-Verlag, Pages: 355-362
Purkayastha S, Aziz O, Athanasiou T, et al., 2004, Does Laparoscopic Surgery Offer Adequate Clearance In Rectal Cancer? - A Discussion, International Journal of Surgery, Vol: 2, Pages: 103-106
Hance J, Rockall T, Darzi A, 2004, Robotics in colorectal surgery, DIGESTIVE SURGERY, Vol: 21, Pages: 339-343, ISSN: 0253-4886
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- Citations: 31
Darzi A, Torkington J, 2004, Laparoscopic Abdominoperineal Resection, Laparoscopic Surgery of the Abdomen, Publisher: Springer New York, Pages: 385-386, ISBN: 9780387984681
Darzi A, Munz Y, 2004, The impact of minimally invasive surgical techniques, ANNUAL REVIEW OF MEDICINE, Vol: 55, Pages: 223-237, ISSN: 0066-4219
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- Citations: 60
Undre S, Moorthy K, Munz Y, et al., 2004, Robot-assisted laparoscopic Heller cardiomyotomy: Preliminary UK results, DIGESTIVE SURGERY, Vol: 21, Pages: 396-400, ISSN: 0253-4886
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- Citations: 11
Bailey CM, Negus R, Goldin R, et al., 2003, The chemokines CCL2 (MCP-1) and CXCL8 (IL-8) are potential therapeutic targets in human colorectal cancer., AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Publisher: AMER ASSOC CANCER RESEARCH, Pages: 6228S-6228S, ISSN: 1078-0432
Alkhamesi NA, Ziprin P, Peck DH, et al., 2003, Molecular mechanisms involved in enhancing peritoneal locoregional metastasis., AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Publisher: AMER ASSOC CANCER RESEARCH, Pages: 6180S-6180S, ISSN: 1078-0432
Rockall TA, Darzi A, 2003, Robot-assisted laparoscopic colorectal surgery, SURGICAL CLINICS OF NORTH AMERICA, Vol: 83, Pages: 1463-+, ISSN: 0039-6109
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- Citations: 39
Khan MS, Bann SD, Darzi A, et al., 2003, Assessing surgical skill., Plast Reconstr Surg, Vol: 112, Pages: 1886-1889, ISSN: 0032-1052
Moorthy K, Munz Y, Sarker SK, et al., 2003, Objective assessment of technical skills in surgery, BMJ-BRITISH MEDICAL JOURNAL, Vol: 327, Pages: 1032-1037, ISSN: 1756-1833
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- Citations: 453
Ziprin P, Ridgway PF, Peck DH, et al., 2003, Laparoscopic enhancement of tumor cell binding to the peritoneum is inhibited by anti-intercellular adhesion molecule-1 monoclonal antibody, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol: 17, Pages: 1812-1817, ISSN: 0930-2794
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- Citations: 10
Kneebone RL, Nestel D, Moorthy K, et al., 2003, Learning the skills of flexible sigmoidoscopy - The wider perspective, MEDICAL EDUCATION, Vol: 37, Pages: 50-58, ISSN: 0308-0110
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- Citations: 52
Kumar BD, Munz Y, Moorthy K, et al., 2003, How can a handful of water assess basic laparoscopic skills?, ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, Vol: 85, Pages: 426-427, ISSN: 0035-8843
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- Citations: 3
Kneebone R, Nestel D, Ratnasothy J, et al., 2003, The use of handheld computers in scenario-based procedural assessments, MEDICAL TEACHER, Vol: 25, Pages: 632-642, ISSN: 0142-159X
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- Citations: 18
Ziprin P, Ridgway PF, Peck DH, et al., 2003, Laparoscopic-type environment enhances mesothelial cell fibrinolytic activity in vitro via a down-regulation of plasminogen activator inhibitor-1 activity., Surgery, Vol: 134, Pages: 758-765, ISSN: 0039-6060
BACKGROUND: Fewer intraperitoneal adhesions have been observed after laparoscopic surgery compared with conventional techniques. The aim of this study is to assess the effect of the pneumoperitoneum on mesothelial cell fibrinolytic activity by use of an in vitro model. METHODS: Human peritoneal mesothelial cells were seeded onto 24-well plates and incubated in carbon dioxide or helium at 5 mm Hg for 4 hours or standard culture conditions. Supernatant was removed for analysis at 0, 24, 48, and 72 hours after gas incubation and analyzed for plasminogen activator activity, total tissue plasminogen activator (tPA), and total plasminogen activator inhibitor-1 (PAI-1) concentrations by use of an enzyme-linked immunosorbent assay. The effect of different insufflation pressures (0, 7, and 14 mm Hg) was also examined. RESULTS: Enhanced plasminogen activator activity was observed at 48 hours and 72 hours from cells exposed to CO(2) (P<.04 each) and helium (P<.05 each) compared with control. This was associated with a decrease in PAI-1 concentrations at 48 and 72 hours in both the CO(2) and helium groups compared with control (P<.03 each, CO(2) vs control; and P<.04 each, helium vs control). No changes in tPA levels were observed. Changes in insufflation pressures did not affect plasminogen activator activity. CONCLUSIONS: These results suggest that incubation of human mesothelial cells with both CO(2) and helium in the absence of oxygen enhances mesothelial cell fibrinolytic activity because of a reduction in PAI-1 concentrations. These changes may participate in the observed reduction in adhesions after laparoscopic surgery relative to open surgery.
Mahmood T, Darzi A, 2003, A study to validate the colonoscopy simulator - It is usefully discriminatory for more than one measurable outcome, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol: 17, Pages: 1583-1589, ISSN: 0930-2794
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- Citations: 47
Shah J, Buckley D, Frisby J, et al., 2003, Reaction time does not predict surgical skill, BRITISH JOURNAL OF SURGERY, Vol: 90, Pages: 1285-1286, ISSN: 0007-1323
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- Citations: 9
Bann S, Kwok KF, Lo CY, et al., 2003, Objective assessment of technical skills of surgical trainees in Hong Kong, BRITISH JOURNAL OF SURGERY, Vol: 90, Pages: 1294-1299, ISSN: 0007-1323
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- Citations: 30
Shah J, Buckley D, Frisby J, et al., 2003, Depth cue reliance in surgeons and medical students, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol: 17, Pages: 1472-1474, ISSN: 0930-2794
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- Citations: 38
Benny PL Lo, Ara Darzi, Guang-Zhong Yang, 2003, Episode Classification for the Analysis of Tissue/Instrument Interaction with Multiple Visual Cues, MICCAI 2003, Publisher: Springer-Verlag
Moorthy K, Munz Y, Dosis A, et al., 2003, The effect of stress-inducing conditions on the performance of a laparoscopic task, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol: 17, Pages: 1481-1484, ISSN: 0930-2794
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- Citations: 110
Huber JW, Taffinder N, Russell RCG, et al., 2003, The effects of different viewing conditions on performance in simulated minimal access surgery, ERGONOMICS, Vol: 46, Pages: 999-1016, ISSN: 0014-0139
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- Citations: 28
Casula RP, Athanasiou T, Cherian A, et al., 2003, Totally Endoscopic Robotically Enhanced Coronary Artery Bypass on the Beating Heart, Journal of the Royal Society of Medicine, Vol: 96, Pages: 400-401, ISSN: 0141-0768
Mackay S, Datta V, Chang A, et al., 2003, Multiple Objective Measures of Skill (MOMS) - A new approach to the assessment of technical ability in surgical trainees, ANNALS OF SURGERY, Vol: 238, Pages: 291-300, ISSN: 0003-4932
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- Citations: 47
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