Imperial College London
Alternate

Professor the Lord Darzi of Denham PC KBE FRS FMedSci HonFREng

Faculty of Medicine, Department of Surgery & Cancer

Co-Director of the IGHI, Professor of Surgery
 
 
 
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Contact

 

+44 (0)20 3312 1310a.darzi

 
 
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Location

 

Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Che:2021:10.1245/s10434-021-10458-4,
author = {Che, Bakri NA and Kwasnicki, R and Dhillon, K and Ghandour, O and Khan, N and Cairns, A and Darzi, A and Leff, D},
doi = {10.1245/s10434-021-10458-4},
journal = {Annals of Surgical Oncology},
pages = {5597--5606},
title = {Objective assessment of post-operative morbidity following breast cancer treatments with wearable activity monitors},
url = {http://dx.doi.org/10.1245/s10434-021-10458-4},
volume = {28},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundCurrent validated tools to measure upper limb dysfunction after breast cancer treatment, such as questionnaires, are prone to recall bias and do not enable comparisons between patients. This study aimed to test the feasibility of wearable activity monitors (WAMs) for achieving a continuous, objective assessment of functional recovery by measuring peri-operative physical activity (PA).MethodsA prospective, single-center, non-randomized, observational study was conducted. Patients undergoing breast and axillary surgery were invited to wear WAMs on both wrists in the peri-operative period and then complete upper limb function (DASH) and quality-of-life (EQ-5D-5L) questionnaires. Statistical analyses were performed to determine the construct validity and concurrent validity of WAMs.ResultsThe analysis included 39 patients with a mean age of 55 ± 13.2 years. Regain of function on the surgically treated side was observed to be an increase of arm activity as a percentage of preoperative levels, with the greatest increase observed between the postoperative days 1 and 2. The PA was significantly greater on the side not treated by surgery than on the surgically treated side after week 1 (mean PA, 75.8% vs. 62.3%; p < 0.0005) and week 2 (mean PA, 91.6% vs. 77.4%; p < 0.005). Subgroup analyses showed differences in recovery trends between different surgical procedures. Concurrent validity was demonstrated by a significant negative moderate correlation between the PA and DASH questionnaires (R = −0.506; p < 0.05).ConclusionThis study demonstrated the feasibility and validity of WAMs to objectively measure postoperative recovery of upper limb function after breast surgery, providing a starting point for personalized rehabilitation through early detection of upper limb physical morbidity.
AU  - Che,Bakri NA
AU  - Kwasnicki,R
AU  - Dhillon,K
AU  - Ghandour,O
AU  - Khan,N
AU  - Cairns,A
AU  - Darzi,A
AU  - Leff,D
DO  - 10.1245/s10434-021-10458-4
EP  - 5606
PY  - 2021///
SN  - 1068-9265
SP  - 5597
TI  - Objective assessment of post-operative morbidity following breast cancer treatments with wearable activity monitors
T2  - Annals of Surgical Oncology
UR  - http://dx.doi.org/10.1245/s10434-021-10458-4
UR  - https://link.springer.com/article/10.1245%2Fs10434-021-10458-4
UR  - http://hdl.handle.net/10044/1/90625
VL  - 28
ER  -
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