Imperial College London
Alternate

Professor the Lord Darzi of Denham PC KBE FRS FMedSci HonFREng

Faculty of Medicine, Department of Surgery & Cancer

Co-Director of the IGHI, Professor of Surgery
 
 
 
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Contact

 

+44 (0)20 3312 1310a.darzi

 
 
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Location

 

Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Taylor:2017:10.1038/ijo.2017.25,
author = {Taylor, MJ and Vlaev, I and Taylor, D and Kulendran, M and Gately, P and Al-Kuwari, H and Darzi, A and Ahmedna, M},
doi = {10.1038/ijo.2017.25},
journal = {INTERNATIONAL JOURNAL OF OBESITY},
pages = {824--827},
title = {Cardiac autonomic regulation as a predictor for childhood obesity intervention success},
url = {http://dx.doi.org/10.1038/ijo.2017.25},
volume = {41},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Childhood obesity is a major public health concern; behavioural interventions induce weight reduction in some, but success is variable. Heart rate variability (HRV) has been associated with impulse control and extent of dieting success. This study investigated the relationship between HRV and post childhood obesity intervention weight-management success, and involved recording the frequency-domain HRV measures ratio between low frequency and high frequency power (LF/HF) and high frequency power (HF), and the time-domain measure, percentage of successive beat-to-beat intervals that differ by more than 50ms (PNN50). It was expected that greater LF/HF and lower HF would be associated with greater post-intervention weight gain, and that greater PNN50 would be associated with greater impulse control. Seventy-four participants aged 9–14 (M=10.7; s.d.: 1.1) attended a weight-management camp, where HRV was recorded. Stop signal reaction time (SSRT) was also recorded as a measure of impulse control. As expected, SSRT was positively associated with pre-intervention body mass (r=0.301, P=0.010) and negatively associated with PNN50 (β=0.29, P=0.031). Post-intervention body mass change was positively associated with LF/HF (β=0.34, P=0.037), but was not associated with HF. Lifestyle interventions may have a greater chance of effectively supporting long-term weight-management for children with lower LF/HF; assessing HRV of obese children may be helpful in informing obesity treatment decisions.
AU  - Taylor,MJ
AU  - Vlaev,I
AU  - Taylor,D
AU  - Kulendran,M
AU  - Gately,P
AU  - Al-Kuwari,H
AU  - Darzi,A
AU  - Ahmedna,M
DO  - 10.1038/ijo.2017.25
EP  - 827
PY  - 2017///
SN  - 0307-0565
SP  - 824
TI  - Cardiac autonomic regulation as a predictor for childhood obesity intervention success
T2  - INTERNATIONAL JOURNAL OF OBESITY
UR  - http://dx.doi.org/10.1038/ijo.2017.25
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000400458200022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/48697
VL  - 41
ER  -
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