Imperial College London

DrAbbasDehghan

Faculty of MedicineSchool of Public Health

Reader in Cardiometabolic Disease Epidemiology
 
 
 
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Contact

 

+44 (0)20 7594 3347a.dehghan CV

 
 
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Location

 

157Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Zhou:2018:ije/dyy016,
author = {Zhou, B and Bentham, J and Di, Cesare M and Bixby, HRH and Danaei, G and Hajifathalian, K and Taddei, C and Carrillo-Larco, R and Khatibzadeh, S and Lugero, C and Peykari, N and Zhang, WZ and Bennett, J and Bilano, V and Stevens, G and Riley, L and Cowan, M and Chen, Z and Hambleton, I and Jackson, RT and Kengne, A-P and Khang, Y-H and Laxmaiah, A and Liu, J and Malekzadeh, R and Neuhauser, H and Soric, M and Starc, G and Sundstrom, J and Woodward, M and Ezzati, M},
doi = {ije/dyy016},
journal = {International Journal of Epidemiology},
pages = {872--883i},
title = {Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1,018 population-based measurement studies with 88.6 million participants},
url = {http://dx.doi.org/10.1093/ije/dyy016},
volume = {47},
year = {2018}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - BackgroundChange in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure.MethodsWe pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean diastolic blood pressure (DBP) and prevalence of raised blood pressure by sex and 10-year age group from 20–29 years to 70–79 years in each study, taking into account complex survey design and survey sample weights, where relevant. We used a linear mixed effect model to quantify the association between (probit-transformed) prevalence of raised blood pressure and age-group- and sex-specific mean blood pressure. We calculated the contributions of change in mean SBP and DBP, and of change in the prevalence-mean association, to the change in prevalence of raised blood pressure.ResultsIn 2005–16, at the same level of population mean SBP and DBP, men and women in South Asia and in Central Asia, the Middle East and North Africa would have the highest prevalence of raised blood pressure, and men and women in the high-income Asia Pacific and high-income Western regions would have the lowest. In most region-sex-age groups where the prevalence of raised blood pressure declined, one half or more of the decline was due to the decline in mean blood pressure. Where prevalence of raised blood pressure has increased, the change was entirely driven by increasing mean blood pressure, offset partly by the change in the prevalence-mean association.ConclusionsChange in mean bloo
AU - Zhou,B
AU - Bentham,J
AU - Di,Cesare M
AU - Bixby,HRH
AU - Danaei,G
AU - Hajifathalian,K
AU - Taddei,C
AU - Carrillo-Larco,R
AU - Khatibzadeh,S
AU - Lugero,C
AU - Peykari,N
AU - Zhang,WZ
AU - Bennett,J
AU - Bilano,V
AU - Stevens,G
AU - Riley,L
AU - Cowan,M
AU - Chen,Z
AU - Hambleton,I
AU - Jackson,RT
AU - Kengne,A-P
AU - Khang,Y-H
AU - Laxmaiah,A
AU - Liu,J
AU - Malekzadeh,R
AU - Neuhauser,H
AU - Soric,M
AU - Starc,G
AU - Sundstrom,J
AU - Woodward,M
AU - Ezzati,M
DO - ije/dyy016
EP - 883
PY - 2018///
SN - 1464-3685
SP - 872
TI - Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1,018 population-based measurement studies with 88.6 million participants
T2 - International Journal of Epidemiology
UR - http://dx.doi.org/10.1093/ije/dyy016
UR - http://hdl.handle.net/10044/1/56671
VL - 47
ER -