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@article{Hammersley:2022:10.1136/openhrt-2021-001918,
author = {Hammersley, D and Buchan, R and Lota, A and Mach, L and Jones, R and Halliday, B and Tayal, U and Meena, D and Dehghan, A and Tzoulaki, I and Baksi, A and Pantazis, A and Roberts, A and Prasad, S and Ware, J},
doi = {10.1136/openhrt-2021-001918},
journal = {Open Heart},
pages = {1--9},
title = {Direct and indirect effect of the COVID-19 pandemic on patients with cardiomyopathy},
url = {http://dx.doi.org/10.1136/openhrt-2021-001918},
volume = {9},
year = {2022}
}

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TY  - JOUR
AB  - Objectives: (i) To evaluate the prevalence and hospitalisation rate of COVID-19 infections amongst patients with dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM) in the Royal Brompton & Harefield Hospital Cardiovascular Research Centre (RBHH CRC) Biobank. (ii) To evaluate the indirect impact of the pandemic on patients with cardiomyopathy through the Heart Hive COVID-19 study. (iii) To assess the impact of the pandemic on national cardiomyopathy-related hospital admissions.Methods: (i) 1,236 patients (703 DCM, 533 HCM) in the RBHH CRC Biobank were assessed for COVID-19 infections and hospitalisations; ii) 207 subjects (131 cardiomyopathy, 76 without heart disease) in the Heart Hive COVID-19 study completed online surveys evaluating physical health, psychological wellbeing, and behavioural adaptations during the pandemic; (iii) 11,447 cardiomyopathy-related hospital admissions across NHS England were studied from NHS Digital Hospital Episode Statistics over 2019-2020. Results: A comparable proportion of patients with cardiomyopathy in the RBHH CRC Biobank had tested positive for COVID-19 compared with the UK population (1.1% vs 1.6%, p=0.14), but a higher proportion of those infected were hospitalised (53.8% vs 16.5%, p=0.002). In the Heart Hive COVID-19 study, more patients with cardiomyopathy felt their physical health had deteriorated due to the pandemic than subjects without heart disease (32.3% vs 13.2%, p=0.004) despite only 4.6% of the cardiomyopathy cohort reporting COVID-19 symptoms. A 17.9% year-on-year reduction in national cardiomyopathy-related hospital admissions was observed in 2020.Conclusion: Patients with cardiomyopathy had similar reported rates of testing positive for COVID-19 to the background population, but those with test-proven infection were hospitalised more frequently. Deterioration in physical health amongst patients could not be explained by COVID-19 symptoms, inferring a significant contribution of the indirect con
AU  - Hammersley,D
AU  - Buchan,R
AU  - Lota,A
AU  - Mach,L
AU  - Jones,R
AU  - Halliday,B
AU  - Tayal,U
AU  - Meena,D
AU  - Dehghan,A
AU  - Tzoulaki,I
AU  - Baksi,A
AU  - Pantazis,A
AU  - Roberts,A
AU  - Prasad,S
AU  - Ware,J
DO  - 10.1136/openhrt-2021-001918
EP  - 9
PY  - 2022///
SN  - 2053-3624
SP  - 1
TI  - Direct and indirect effect of the COVID-19 pandemic on patients with cardiomyopathy
T2  - Open Heart
UR  - http://dx.doi.org/10.1136/openhrt-2021-001918
UR  - https://openheart.bmj.com/content/9/1/e001918
UR  - http://hdl.handle.net/10044/1/96212
VL  - 9
ER  -

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