Imperial College London

DrArmandoDel Rio Hernandez

Faculty of EngineeringDepartment of Bioengineering

Senior Lecturer



+44 (0)20 7594 5187a.del-rio-hernandez




308Bessemer BuildingSouth Kensington Campus






Dr. Armando E. del Río Hernández is a Senior Lecturer in the Department of Bioengineering at Imperial College London, UK. His research is focused on the field of cellular and molecular mechanotransduction, the study of the mechanisms by which cells and molecules transform mechanical stimuli into biochemical signals. For more information, please click this link.

Enquires from motivated and exceptional students and postdocs to work in his group are always welcome. Please send full CV and cover letter to:

 In the Department of Bioengineering, Dr. del Río Hernández is the Director of the MRes in Bioengineering, which offers the opportunity for graduate students to begin their careers in scientific research.

Contact information

Office: Bessemer building (number 11 in the South Kensington campus map)

Room 308, 3rd Floor

Department of Bioengineering

Imperial College London

South Kensington Campus

London SW7 2AZ

United Kingdom

Telephone: 44 (0) 20 7594 5187

Skype: armando.delrio



    Selected Publications

    Journal Articles

    Cortes E, Lachowski D, Rice A, et al., 2018, RAR-β is downregulated in HCC & cirrhosis and its expression inhibits myosin-driven activation and durotaxis in hepatic stellate cells, Hepatology, ISSN:0270-9139

    Lachowski D, Cortes E, Robinson B, et al., 2018, FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis, The FASEB Journal, Vol:32, ISSN:0892-6638, Pages:1099-1107

    Chronopoulos A, Lieberthal TJ, Hernandez AEDR, 2017, Exosomes as a platform for 'liquid biopsy' in pancreatic cancer, Convergent Science Physical Oncology, Vol:3, ISSN:2057-1739

    Chronopoulos A, Lieberthal TJ, Hernandez AEDR, 2017, Pancreatic cancer: a mechanobiology approach, Convergent Science Physical Oncology, Vol:3, ISSN:2057-1739

    Attwood SJ, Cortes E, Haining AWM, et al., 2016, Adhesive ligand tether length affects the size and length of focal adhesions and influences cell spreading and attachment, Scientific Reports, Vol:6, ISSN:2045-2322

    Chronopoulos A, Robinson B, Sarper M, et al., 2016, ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion, Nature Communications, Vol:7, ISSN:2041-1723

    Sarper M, Cortes E, Lieberthal T, et al., 2016, ATRA modulates mechanical activation of TGF-β by pancreatic stellate cells, Scientific Reports, Vol:6, ISSN:2045-2322

    Haining AWM, Lieberthal TJ, Hernandez ADR, 2016, Talin: a mechanosensitive molecule in health and disease, The FASEB Journal, Vol:30, ISSN:0892-6638, Pages:2073-2085

    Roca-Cusachs P, del Rio A, Puklin-Faucher E, et al., 2013, Integrin-dependent force transmission to the extracellular matrix by alpha-actinin triggers adhesion maturation, Proceedings of the National Academy of Sciences of the United States of America, Vol:110, ISSN:0027-8424, Pages:E1361-E1370

    Roca-Cusachs P, Gauthier NC, del Rio A, et al., 2009, Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction, Proceedings of the National Academy of Sciences of the United States of America, Vol:106, ISSN:0027-8424, Pages:16245-16250

    del Rio A, Perez-Jimenez R, Liu R, et al., 2009, Stretching Single Talin Rod Molecules Activates Vinculin Binding, Science, Vol:323, ISSN:0036-8075, Pages:638-641

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