Imperial College London
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ProfessorAndreaCrisanti

Faculty of Natural Sciences, Department of Life Sciences

Professor of Molecular Parasitology
 
 
 
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Contact

 

+44 (0)20 7594 5395a.drcrisanti

 
 
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Assistant

 

Mrs Lucy Collyns +44 (0)20 7594 5395

 
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Location

 

549Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Burt:2018:10.1021/acschembio.7b01031,
author = {Burt, A and Crisanti, A},
doi = {10.1021/acschembio.7b01031},
journal = {ACS Chemical Biology},
pages = {343--346},
title = {Gene drive: evolved and synthetic},
url = {http://dx.doi.org/10.1021/acschembio.7b01031},
volume = {13},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Drive is a process of accelerated inheritance from one generation to the next that allows some genes to spread rapidly through populations even if they do not contribute to-or indeed even if they detract from-organismal survival and reproduction. Genetic elements that can spread by drive include gametic and zygotic killers, meiotic drivers, homing endonuclease genes, B chromosomes, and transposable elements. The fact that gene drive can lead to the spread of fitness-reducing traits (including lethality and sterility) makes it an attractive process to consider exploiting to control disease vectors and other pests. There are a number of efforts to develop synthetic gene drive systems, particularly focused on the mosquito-borne diseases that continue to plague us.
AU  - Burt,A
AU  - Crisanti,A
DO  - 10.1021/acschembio.7b01031
EP  - 346
PY  - 2018///
SN  - 1554-8929
SP  - 343
TI  - Gene drive: evolved and synthetic
T2  - ACS Chemical Biology
UR  - http://dx.doi.org/10.1021/acschembio.7b01031
UR  - https://www.ncbi.nlm.nih.gov/pubmed/29400944
UR  - http://hdl.handle.net/10044/1/57166
VL  - 13
ER  -
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