Imperial College London
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DrAndrewEdwards

Faculty of Medicine, Department of Infectious Disease

Director of Postgraduate Education & Senior Lecturer
 
 
 
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Contact

 

a.edwards Website

 
 
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Location

 

5.40AFlowers buildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Edwards:2011:10.1016/j.tim.2010.12.005,
author = {Edwards, AM and Massey, RC},
doi = {10.1016/j.tim.2010.12.005},
journal = {Trends Microbiol.},
pages = {184--190},
title = {How does Staphylococcus aureus escape the bloodstream?},
url = {http://dx.doi.org/10.1016/j.tim.2010.12.005},
volume = {19},
year = {2011}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Staphylococcus aureus is a major cause of bacteraemia, which frequently leads to infective endocarditis, osteomyelitis, septic arthritis and metastatic abscess formation. The development of these secondary infections is due to bacterial dissemination from the blood into surrounding tissues and is associated with significantly increased morbidity and mortality. Despite the importance of S. aureus extravasation in disease progression, there is relatively little understanding of the molecular mechanisms by which this pathogen crosses the endothelial barrier and establishes new sites of infection. Recent work has identified a number of putative routes by which S. aureus can escape the bloodstream. In this article we review these new developments and set them in the context of strategies used by other established pathogens to traverse cellular barriers
AU  - Edwards,AM
AU  - Massey,RC
DO  - 10.1016/j.tim.2010.12.005
EP  - 190
PY  - 2011///
SP  - 184
TI  - How does Staphylococcus aureus escape the bloodstream?
T2  - Trends Microbiol.
UR  - http://dx.doi.org/10.1016/j.tim.2010.12.005
UR  - pm:21227700
VL  - 19
ER  -
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