Imperial College London

DrAmandaFoust

Faculty of EngineeringDepartment of Bioengineering

Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 1055a.foust Website CV

 
 
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Location

 

RSMRoyal School of MinesSouth Kensington Campus

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Summary

 

Overview

The ability to manipulate and track neuronal communication is essential to understanding the mechanisms underlying our sensations, perceptions, thoughts, emotions and actions. With a growing toolbox of optical dyes, genetic sensors and actuators, Neuroscience has made science fiction-scale progress toward realizing this important prerequisite for neural circuit reverse engineering. A parallel revolution in photonics research is taking shape to exploit the full potential of photo-molecular tools for brain circuit interrogation. My goal is to engineer bridges between recent optical technology and Neurophysiologists endeavoring to close the loop between theory and experimentation.

Fields of Expertise

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Intrinsic imaging (scattering, absorbtion, birefringence)
Functional fluoroscence imaging (voltage, calcium)
Two-photon microscopy
Computer-generated holography
Temporal focusing 
Electrophysiology (patch clamp, extracellular)
Computational neuroscience
Optomechanical design and prototyping
Functional image acquisition and analysis software

Training, Professional Experience

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2016-present   Royal Academy of Engineering Research Fellow
2018-present   Lecturer    Imperial College London
                                          Dept. Bioengineering
                                          Centre for Neurotechnology

2015                Postdoc    Imperial College London
                                         Dept. Bioengineering
                                         Centre for Neurotechnology
                                         Advisor: Simon Schultz, Ph.D.

2013-2014       Postdoc    University Paris Descartes
                                         Dept. Neurophotonics
                                         Wavefront Engineering
                                         Advisor: Valentina Emiliani, Ph.D.

2007-2010       M.Phil.      Yale University
2007-2012       Ph.D.        With Distinction
                                         Neuroscience, Dept. Neurobiology
                                         Advisor: David A. McCormick, Ph.D.

2002-2006       B.S.          Washington State University, 
                                         Summa cum laude
                                         Neuroscience
                                         Emphasis EE and computation 
                                         Advisor: David M. Rector, Ph.D.


Research Support

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Integrated Biological Imaging Network Pump-prime
Role: Principal Investigator
9/2020-12/2020
Imaging membrane voltage light fields: new views into the pathophysiology of cancer

EPSRC Capital Award for Early Career Researchers
Role: Principal Investigator
11/2018-5/2020
Instrument for characterizing two-photon absorption and action spectra of red and near-infrared fluorophores and membrane conductance actuators

BBSRC Research Grant BB/R009007/1
Role: Principal Investigator
6/2018-5/2021
Two-photon Light Field with Neuro-active Sensing for Fast Volumetric Neural Microcircuit Readout

Wellcome Seed Award
Role: Principal Investigator
10/2016 - 9/2018
Holographic Induction of Neural Circuit Plasticity

Royal Academy of Engineering Research Fellowship       
Role: Research Fellow
1/2016 - 12/2020
Holographic Light Shaping for Reverse
Engineering Neural Circuit Learning

Imperial College London Junior Research Fellowship      
Declined
Two-photon Computer-Generated Holography for
Investigation of Dendritic Information Processing

U01 NS090501-01 (US NIH, B.R.A.I.N.)
Role: Co-Investigator
1/2015 - 12/2017
Three Dimensional Computer-Generated Holography 
For Neural Circuit Reverse Engineering

NSF Postdoctoral International Research Fellowship        
Role: Post-Doctoral Fellow
1/2013 - 12/2014
Scanless Two-Photon Voltage Imaging of Live Neuron
Activity with Holographic Wavefront Shaping

Whitaker Foundation Post-doctoral Fellowship
Awarded 2012 (declined)

NRSA F31 NS 070368-01 (NIH/NINDS)
Role: Principal Investigator
9/2010 - 5/2012
Optical Imaging of Information Processing in CNS Axons

NSF Graduate Research Fellowship
Role: Pre-Doctoral Fellow
9/2007 - 8/2010