Research Areas
Molecular characterisation of Pancreatic Ductal Adenocarcinoma (PDAC) and pancreatic cystic tumours by:
- Immunohistochemistry
- microRNA and gene profiling of tissues, EUS-FNAs, blood and bile
- Next-Generation Sequencing (RNA-Seq and small RNA-Seq)
- Circulating Tumour Cells (CTCs)
- In situ hybridisation (ISH)
- Single-Cell Sequencing
- Mouse-models of PDAC and metastasis assays
RESEARCH DETAILS CAN BE FOUND HERE
Other research areas
- microRNAs in Breast, Colorectal, Ovarian and Neuroendocrine tumours
- Molecular characterisation of Colorectal Liver Metastases after induction of Liver Hypertrophy
REVIEWER FOR FOLLOWING JOURNALS
Collaborators
Prof. Oliver Strobel, University of Heidelberg, 2017
Prof Steve Pereira, Prof Steve Pereira, 2017
Dr Anguraj Sadanandam, Dr Anguraj Sadanandam, Institute of Cancer Research, 2017
Prof. Susan Galandiuk, University of Louisville, USA, 2016
Prof. Chris Wolfgang, Johns Hopkins, 2014
Prof. Andrea Frilling, Endocrine Surgery, 2013
Mr Nigel B. Jamieson, University of Glasgow, 2012
Dr Niccola Funel, University of Pisa, Italy, 2010
Dr Elisa Giovannetti, VU University Medical Center, Amsterdam, 2010
Guest Lectures
microRNAs in the diagnosis and prognosis of Pancreatic Cancer, Price Institute of Surgical Research, University of Louisville, KY, USA, 2016
Research Student Supervision
Fajardo,A, PhD student - Impact of preoperative manipulation for liver hypertrophy on liver regeneration, tumour growth and the transcriptome
Gall,TMH, MD (Res) - December 2015 - Predicting Disease Recurrence in Pancreatic Ductal Adenocarcinoma
Liu,D, PhD student - MIRABILE study
Malczewska,A, Circulating MicroRNAs in Small Bowel Neuroendocrine Tumors – a novel tool for diagnosis and assessment of effectiveness of surgical resection
Mato Prado,M, PhD student - MicroRNAs as bile-based biomarkers for pancreatic and biliary tract cancers
Upton,F, MRes - Plasma EVs as biomarkers for Pancreaticobiliary cancers