Imperial College London

DrAnnaHansell

Faculty of MedicineSchool of Public Health

Visiting Professor
 
 
 
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a.hansell

 
 
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UG42Medical SchoolSt Mary's Campus

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Summary

 

Publications

Publication Type
Year
to

137 results found

Williams B, Douglas P, Barcelo AR, Hansell AL, Hayes Eet al., 2019, Estimating Aspergillus fumigatus exposure from outdoor composting activities in England between 2005 and 14, WASTE MANAGEMENT, Vol: 84, Pages: 235-244, ISSN: 0956-053X

JOURNAL ARTICLE

Morgan RL, Thayer KA, Santesso N, Holloway AC, Blain R, Eftim SE, Goldstone AE, Ross P, Ansari M, Akl E, Filippini T, Hansell A, Meerpohl JJ, Mustafa RA, Verbeek J, Vinceti M, Whaley P, Schunemann HJet al., 2019, A risk of bias instrument for non-randomized studies of exposures: A users' guide to its application in the context of GRADE, ENVIRONMENT INTERNATIONAL, Vol: 122, Pages: 168-184, ISSN: 0160-4120

JOURNAL ARTICLE

Wang Y, Pirani M, Hansell AL, Richardson S, Blangiardo Met al., 2019, Using ecological propensity score to adjust for missing confounders in small area studies., Biostatistics, Vol: 20, Pages: 1-16

Small area ecological studies are commonly used in epidemiology to assess the impact of area level risk factors on health outcomes when data are only available in an aggregated form. However, the resulting estimates are often biased due to unmeasured confounders, which typically are not available from the standard administrative registries used for these studies. Extra information on confounders can be provided through external data sets such as surveys or cohorts, where the data are available at the individual level rather than at the area level; however, such data typically lack the geographical coverage of administrative registries. We develop a framework of analysis which combines ecological and individual level data from different sources to provide an adjusted estimate of area level risk factors which is less biased. Our method (i) summarizes all available individual level confounders into an area level scalar variable, which we call ecological propensity score (EPS), (ii) implements a hierarchical structured approach to impute the values of EPS whenever they are missing, and (iii) includes the estimated and imputed EPS into the ecological regression linking the risk factors to the health outcome. Through a simulation study, we show that integrating individual level data into small area analyses via EPS is a promising method to reduce the bias intrinsic in ecological studies due to unmeasured confounders; we also apply the method to a real case study to evaluate the effect of air pollution on coronary heart disease hospital admissions in Greater London.

JOURNAL ARTICLE

Ghosh RE, Freni-Sterrantino A, Douglas P, Parkes B, Fecht D, de Hoogh K, Fuller G, Gulliver J, Font A, Smith RB, Blangiardo M, Elliott P, Toledano MB, Hansell ALet al., 2019, Fetal growth, stillbirth, infant mortality and other birth outcomes near UK municipal waste incinerators; retrospective population based cohort and case-control study, ENVIRONMENT INTERNATIONAL, Vol: 122, Pages: 151-158, ISSN: 0160-4120

JOURNAL ARTICLE

Piel FB, Parkes BL, Daby H, Hansell AL, Elliott Pet al., 2018, The challenge of opt-outs from NHS data: a small-area perspective, JOURNAL OF PUBLIC HEALTH, Vol: 40, Pages: E594-E600, ISSN: 1741-3842

JOURNAL ARTICLE

Pierotti L, Schofield SJ, Collett D, Fecht D, De Hoogh K, Hansell AL, Dark J, Cullinan Pet al., 2018, Traffic-related air pollution and solid organ transplant failure in Great Britain: A retrospective cohort study, JOURNAL OF TRANSPORT & HEALTH, Vol: 10, Pages: 124-131, ISSN: 2214-1405

JOURNAL ARTICLE

Fecht D, Jones A, Hill T, Lindfield T, Thomson R, Hansell AL, Shukla Ret al., 2018, Inequalities in rural communities: adapting national deprivation indices for rural settings, JOURNAL OF PUBLIC HEALTH, Vol: 40, Pages: 419-425, ISSN: 1741-3842

JOURNAL ARTICLE

Cai Y, Hodgson S, Blangiardo M, Gulliver J, Morley D, Fecht D, Vienneau D, de Hoogh K, Key T, Hveem K, Elliott P, Hansell ALet al., 2018, Road traffic noise, air pollution and incident cardiovascular disease: A joint analysis of the HUNT, EPIC-Oxford and UK Biobank cohorts, ENVIRONMENT INTERNATIONAL, Vol: 114, Pages: 191-201, ISSN: 0160-4120

JOURNAL ARTICLE

Ghosh RE, Berild JD, Sterrantino AF, Toledano MB, Hansell ALet al., 2018, Birth weight trends in England and Wales (1986-2012): babies are getting heavier, ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, Vol: 103, Pages: F264-F270, ISSN: 1359-2998

JOURNAL ARTICLE

Gulliver J, Elliott P, Henderson J, Hansell AL, Vienneau D, Cai Y, McCrea A, Garwood K, Boyd A, Neal L, Agnew P, Fecht D, Briggs D, de Hoogh Ket al., 2018, Local- and regional-scale air pollution modelling (PM10) and exposure assessment for pregnancy trimesters, infancy, and childhood to age 15 years: Avon Longitudinal Study of Parents And Children (ALSPAC), ENVIRONMENT INTERNATIONAL, Vol: 113, Pages: 10-19, ISSN: 0160-4120

JOURNAL ARTICLE

Hansell AL, Bakolis I, Cowie CT, Belousova EG, Ng K, Weber-Chrysochoou C, Britton WJ, Leeder SR, Tovey ER, Webb KL, Toelle BG, Marks GBet al., 2018, Childhood fish oil supplementation modifies associations between traffic related air pollution and allergic sensitisation, ENVIRONMENTAL HEALTH, Vol: 17, ISSN: 1476-069X

JOURNAL ARTICLE

Douglas P, Robertson S, Gay R, Hansell AL, Gant TWet al., 2018, A systematic review of the public health risks of bioaerosols from intensive farming, INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, Vol: 221, Pages: 134-173, ISSN: 1438-4639

JOURNAL ARTICLE

Cai Y, Hansell A, Hodgson S, Elliott P, Fecht D, Gulliver J, Key T, de Hoogh K, Hveem K, Morley D, Vienneau D, Blangiardo Met al., Road traffic noise, air pollution and incident cardiovascular disease: a joint analysis of the HUNT, EPIC-Oxford and UK Biobank cohorts, Environment International, ISSN: 0160-4120

Background: This study aimed to investigate the effects of long-term exposure to road traffic noiseand air pollutionon incident cardiovascular disease (CVD)in three large cohorts: HUNT, EPIC-Oxford and UK Biobank. Methods: In pooled complete-casesample of the three cohorts from Norway and the United Kingdom(N=355,732), 21,081 incident all CVD cases including 5,259ischemic heart disease (IHD)and 2,871cerebrovascular cases were ascertained between baseline (1993-2010)and end of follow-up (2008-2013)through medical recordlinkage. Annual mean 24-hour weighted road traffic noise(Lden) and air pollution (particulate matter with aerodynamic diameter ≤10 μm [PM10],≤2.5 μm [PM2.5]andnitrogen 39dioxide[NO2])exposure at baseline address was modelled using a simplified version of the Common Noise Assessment Methods in Europe (CNOSSOS-EU)and European-wide Land Use Regression models.Individual-level covariate data were harmonised and physically pooled across the three cohorts. Analysis was via Cox proportional hazard model with mutual adjustmentsforboth noise and air pollution andpotential confounders. Results: No significant associations were found between annual mean Ldenand incidentCVD,IHD or cerebrovascular disease in the overall populationexcept that the association withincident IHD was significantamong current-smokers.In the fully adjusted models including adjustmentfor Lden, an interquartile range (IQR) higher PM10(4.1μg/m3) or PM2.5(1.4μg/m3) was associated witha5.8% (95%CI: 2.5%-9.3%) and 3.7% (95%CI: 0.2%-7.4%) higherrisk for all incident CVD respectively. No significant associations were found between NO2and any of the CVD outcomes. Conclusions: We found suggestive evidence of a possible association between road traffic noise and incident IHD, consistent with current literature. Long-term particulate air pollution exposure, even at concentrations below current European air quality standards, w

JOURNAL ARTICLE

Smith RB, Fecht D, Gulliver J, Beevers SD, Dajnak D, Blangiardo M, Ghosh RE, Hansell AL, Kelly FJ, Anderson HR, Toledano MBet al., 2017, Impact of London's road traffic air and noise pollution on birth weight: retrospective population based cohort study, BMJ-BRITISH MEDICAL JOURNAL, Vol: 359, ISSN: 1756-1833

JOURNAL ARTICLE

Dimakopoulou K, Koutentakis K, Papageorgiou I, Kasdagli M-I, Haralabidis AS, Sourtzi P, Samoli E, Houthuijs D, Swart W, Hansell AL, Katsouyanni Ket al., 2017, Is aircraft noise exposure associated with cardiovascular disease and hypertension? Results from a cohort study in Athens, Greece, OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, Vol: 74, Pages: 830-837, ISSN: 1351-0711

JOURNAL ARTICLE

Doiron D, de Hoogh K, Probst-Hensch N, Mbatchou S, Eeftens M, Cai Y, Schindler C, Fortier I, Hodgson S, Gaye A, Stolk R, Hansell Aet al., 2017, Residential Air Pollution and Associations with Wheeze and Shortness of Breath in Adults: A Combined Analysis of Cross-Sectional Data from Two Large European Cohorts., Environ Health Perspect, Vol: 125

BACKGROUND: Research examining associations between air pollution exposure and respiratory symptoms in adults has generally been inconclusive. This may be related in part to sample size issues, which also preclude analysis in potentially vulnerable subgroups. OBJECTIVES: We estimated associations between air pollution exposures and the prevalence of wheeze and shortness of breath using harmonized baseline data from two very large European cohorts, Lifelines (2006-2013) and UK Biobank (2006-2010). Our aim was also to determine whether the relationship between air pollution and respiratory symptom prevalence differed between individuals with different characteristics. METHODS: Cross-sectional analyses explored associations between prevalence of self-reported wheeze and shortness of breath and annual mean particulate matter with aerodynamic diameter <2.5μm, 2.5-10μm, and <10μm (PM2.5, PMcoarse, and PM10, respectively) and nitrogen dioxide (NO2) concentrations at place of residence using logistic regression. Subgroup analyses and tests for interaction were performed for age, sex, smoking status, household income, obesity status, and asthma status. RESULTS: All PM exposures were associated with respiratory symptoms based on single-pollutant models, with the largest associations seen for PM2.5 with prevalence of wheezing {odds ratio (OR)=1.16 per 5μg/m³ [95% confidence interval (CI): 1.11, 1.21]} and shortness of breath [OR=1.61 per 5μg/m³ (95% CI: 1.45, 1.78)]. The association between shortness of breath and a 5-μg/m³ increment in PM2.5 was significantly higher for individuals from lower-[OR=1.73 (95% CI: 1.52, 1.97)] versus higher-income households [OR=1.31 (95% CI: 1.11, 1.55); p-interaction=0.005), whereas the association between PM2.5 and wheeze was limited to lower-income participants [OR=1.30 (95% CI: 1.22, 1.38) vs. OR=1.02; (95% CI: 0.96, 1.08); p-interaction<0.001]. Exposure to NO2 also showed positive associations with

JOURNAL ARTICLE

Cai Y, Hansell AL, Blangiardo M, Burton PR, de Hoogh K, Doiron D, Fortier I, Gulliver J, Hveem K, Mbatchou S, Morley D, Stolk RP, Zijlema WL, Elliott P, Hodgson Set al., 2017, Long-termexposure to road traffic noise, ambient air pollution, and cardiovascular risk factors in the HUNT and lifelines cohorts, EUROPEAN HEART JOURNAL, Vol: 38, Pages: 2290-+, ISSN: 0195-668X

JOURNAL ARTICLE

Douglas P, Freni-Sterrantino A, Sanchez ML, Ashworth DC, Ghosh RE, Fecht D, Font A, Blangiardo M, Gulliver J, Toledano MB, Elliott P, de Hoogh K, Fuller GW, Hansell ALet al., 2017, Estimating Particulate Exposure from Modern Municipal Waste Incinerators in Great Britain, ENVIRONMENTAL SCIENCE & TECHNOLOGY, Vol: 51, Pages: 7511-7519, ISSN: 0013-936X

JOURNAL ARTICLE

Hansell A, Cai Y, Gulliver J, 2017, Cardiovascular Health Effects of Road Traffic Noise, Environmental Impacts of Road Vehicles Past, Present and Future, Publisher: Issues in Environmental Scienc, ISBN: 9781782628927

This book is a comprehensive source of authoritative information for students studying pollution, and for policy-makers concerned with vehicle emissions and road traffic impacts more generally.

BOOK CHAPTER

Cai Y, Hodgson S, Blangiardo M, De Hoogh K, Morley D, Gulliver J, Hveem K, Elliott P, Hansell Aet al., 2017, Ambient Air Pollution, Traffic Noise And Adult-Onset Asthma: The Hunt Study, Norway, International Conference of the American-Thoracic-Society (ATS), Publisher: American Thoracic Society, ISSN: 1073-449X

CONFERENCE PAPER

Basner M, Clark C, Hansell A, Hileman JI, Janssen S, Shepherd K, Sparrow Vet al., 2017, Aviation Noise Impacts: State of the Science, Noise and Health, Vol: 19, Pages: 41-50, ISSN: 1463-1741

Noise is defined as “unwanted sound.” Aircraft noise is one, if not the most detrimental environmental effect of aviation. It can cause community annoyance, disrupt sleep, adversely affect academic performance of children, and could increase the risk for cardiovascular disease of people living in the vicinity of airports. In some airports, noise constrains air traffic growth. This consensus paper was prepared by the Impacts of Science Group of the Committee for Aviation Environmental Protection of the International Civil Aviation Organization and summarizes the state of the science of noise effects research in the areas of noise measurement and prediction, community annoyance, children’s learning, sleep disturbance, and health. It also briefly discusses civilian supersonic aircraft as a future source of aviation noise.

JOURNAL ARTICLE

Wain LV, Shrine N, Artigas MS, Erzurumluoglu AM, Noyvert B, Bossini-Castillo L, Obeidat M, Henrys AP, Portelli MA, Hall RJ, Billington CK, Rimington TL, Fenech AG, John C, Blake T, Jackson VE, Allen RJ, Prins BP, Campbell A, Porteous DJ, Jarvelin M-R, Wielscher M, Jamess AL, Hui J, Wareham NJ, Zhao JH, Wilson JF, Joshi PK, Stubbe B, Rawal R, Schulz H, Imboden M, Probst-Hensch NM, Karrasch S, Gieger C, Deary IJ, Harris SE, Marten J, Rudan I, Enroth S, Gyllensten U, Kerr SM, Polasek O, Kahonen M, Surakka I, Vitart V, Hayward C, Lehtimaki T, Raitakari OT, Evans DM, Henderson AJ, Pennell CE, Wang CA, Sly PD, Wan ES, Busch R, Hobbs BD, Litonjua AA, Sparrow DW, Gulsvik A, Bakke PS, Crapo JD, Beaty TH, Hansel NN, Mathias RA, Ruczinski I, Barnes KC, Bosse Y, Joubert P, van den Berge M, Brandsma C-A, Pare PD, Sin DD, Nickle DC, Hao K, Gottesman O, Dewey FE, Bruse SE, Carey DJ, Kirchner HL, Jonsson S, Thorleifsson G, Jonsdottir I, Gislason T, Stefansson K, Schurmann C, Nadkarni G, Bottinger EP, Loos RJF, Walters RG, Chen Z, Millwood IY, Vaucher J, Kurmi OP, Li L, Hansell AL, Brightling C, Zeggini E, Cho MH, Silverman EK, Sayers I, Trynka G, Morris AP, Strachan DP, Halls IP, Tobin MDet al., 2017, Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets, NATURE GENETICS, Vol: 49, Pages: 416-425, ISSN: 1061-4036

JOURNAL ARTICLE

Dehbi H-M, Blangiardo M, Gulliver J, Fecht D, de Hoogh K, Al-Kanaani Z, Tillin T, Hardy R, Chaturvedi N, Hansell ALet al., 2017, Air pollution and cardiovascular mortality with over 25 years follow-up: A combined analysis of two British cohorts, ENVIRONMENT INTERNATIONAL, Vol: 99, Pages: 275-281, ISSN: 0160-4120

JOURNAL ARTICLE

Cai Y, Zijlema WL, Doiron D, Blangiardo M, Burton PR, Fortier I, Gaye A, Gulliver J, de Hoogh K, Hveem K, Mbatchou S, Morley DW, Stolk RP, Elliott P, Hansell AL, Hodgson Set al., 2017, Ambient air pollution, traffic noise and adult asthma prevalence: a BioSHaRE approach, EUROPEAN RESPIRATORY JOURNAL, Vol: 49, ISSN: 0903-1936

JOURNAL ARTICLE

Zijlema W, Cai Y, Doiron D, Mbatchou S, Fortier I, Gulliver J, de Hoogh K, Morley D, Hodgson S, Elliott P, Key T, Kongsgard H, Hveem K, Gaye A, Burton P, Hansell A, Stolk R, Rosmalen Jet al., 2017, Corrigendum to "Road traffic noise, blood pressure and heart rate: Pooled analyses of harmonized data from 88,336 participants" [Envrion. Res. 151 (2016) 804-813], Environmental Research, Vol: 152, Pages: 520-520, ISSN: 0013-9351

JOURNAL ARTICLE

Douglas P, Tyrrel SF, Kinnersley RP, Whelan M, Longhurst PJ, Hansell AL, Walsh K, Pollard SJT, Drew GHet al., 2017, Predicting Aspergillus fumigatus exposure from composting facilities using a dispersion model: A conditional calibration and validation, INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, Vol: 220, Pages: 17-28, ISSN: 1438-4639

JOURNAL ARTICLE

Halonen JI, Dehbi H-M, Hansell AL, Gulliver J, Fecht D, Blangiardo M, Kelly FJ, Chaturvedi N, Kivimaki M, Tonne Cet al., 2017, Associations of night-time road traffic noise with carotid intima-media thickness and blood pressure: The Whitehall II and SABRE study cohorts, ENVIRONMENT INTERNATIONAL, Vol: 98, Pages: 54-61, ISSN: 0160-4120

JOURNAL ARTICLE

Bartington SE, Bakolis I, Devakumar D, Kurmi OP, Gulliver J, Chaube G, Manandhar DS, Saville NM, Costello A, Osrin D, Hansell AL, Ayres JGet al., 2017, Patterns of domestic exposure to carbon monoxide and particulate matter in households using biomass fuel in Janakpur, Nepal, ENVIRONMENTAL POLLUTION, Vol: 220, Pages: 38-45, ISSN: 0269-7491

JOURNAL ARTICLE

Bakolis I, Kelly R, Fecht D, Best N, Millett C, Garwood K, Elliott P, Hansell AL, Hodgson Set al., 2016, Protective Effects of Smoke-free Legislation on Birth Outcomes in England A Regression Discontinuity Design, EPIDEMIOLOGY, Vol: 27, Pages: 810-818, ISSN: 1044-3983

JOURNAL ARTICLE

Boulieri A, Hansell A, Blangiardo M, 2016, Investigating trends in asthma and COPD through multiple data sources: A small area study, SPATIAL AND SPATIO-TEMPORAL EPIDEMIOLOGY, Vol: 19, Pages: 28-36, ISSN: 1877-5845

JOURNAL ARTICLE

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