Publications
563 results found
Aljuaid M, Elmontsri M, Edvardsson D, et al., Psychometric Evaluation of the Arabic Language Person-Centred Climate Questionnaire – Staff Version, Journal of Nursing Management, ISSN: 0966-0429
Cliffe C, Hillyard M, Joseph A, et al., The transgender patient in primary care: practical advice for a ten minute consultation, British Journal of General Practice Open, ISSN: 1478-5242
With referrals to gender identity clinics rising rapidly, GPs are more likely to meet patients who are transgender or diagnosed with gender dysphoria [1]. Teaching on transgender medicine is lacking in both undergraduate and postgraduate curricula, leading to a perceived lack of expertise within this area. Furthermore, General Medical Council (GMC) guidelines on the GP’s role in prescribing are vague, resulting in some controversy. As waiting lists for appointments at specialist clinics are often at least 18 months, primary care physicians will be increasingly involved in the initiation of the transition process.
Cliffe C, Hillyard M, Joseph A, et al., The child transgender patient in primary care: practical advice for a ten minute consultation, British Journal of General Practice Open, ISSN: 1478-5242
There are complex ethical and legal issues for children who are non-conforming to their assigned gender. The main role of the general practitioner is providing support and referral to a specialist centre, usually the Tavistock and Portman Gender Identity Development Service (GIDS) in London, for ongoing psychological assessment. This needs to be done urgently if there are concerns over self-harm or suicide; or the child is at or close to age of puberty. At the age of 17, the adolescent can be referred to an adult specialist service.
Hayhoe BWJ, Majeed A, Perneczky R, GP referrals to memory clinics: are referral criteria delaying the diagnosis of dementia?, Journal of the Royal Society of Medicine, ISSN: 1758-1095
Achana F, Petrou S, Khan K, et al., 2017, A methodological framework for assessing agreement between cost-effectiveness outcomes estimated using alternative sources of data on treatment costs and effects for trial-based economic evaluations., Eur J Health Econ
A new methodological framework for assessing agreement between cost-effectiveness endpoints generated using alternative sources of data on treatment costs and effects for trial-based economic evaluations is proposed. The framework can be used to validate cost-effectiveness endpoints generated from routine data sources when comparable data is available directly from trial case report forms or from another source. We illustrate application of the framework using data from a recent trial-based economic evaluation of the probiotic Bifidobacterium breve strain BBG administered to babies less than 31 weeks of gestation. Cost-effectiveness endpoints are compared using two sources of information; trial case report forms and data extracted from the National Neonatal Research Database (NNRD), a clinical database created through collaborative efforts of UK neonatal services. Focusing on mean incremental net benefits at £30,000 per episode of sepsis averted, the study revealed no evidence of discrepancy between the data sources (two-sided p values >0.4), low probability estimates of miscoverage (ranging from 0.039 to 0.060) and concordance correlation coefficients greater than 0.86. We conclude that the NNRD could potentially serve as a reliable source of data for future trial-based economic evaluations of neonatal interventions. We also discuss the potential implications of increasing opportunity to utilize routinely available data for the conduct of trial-based economic evaluations.
Afshin A, Forouzanfar MH, Reitsma MB, et al., 2017, Health Effects of Overweight and Obesity in 195 Countries over 25 Years, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 377, Pages: 13-27, ISSN: 0028-4793
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- Citations: 1
Ahmed F, Ahmed N, Stubbens A, et al., 2017, Is there a role for smaller hospitals in the future NHS?, BRITISH JOURNAL OF HOSPITAL MEDICINE, Vol: 78, Pages: 424-425, ISSN: 1750-8460
Alshaikh MK, Filippidis FT, Al-Omar HA, et al., 2017, The ticking time bomb in lifestyle-related diseases among women in the Gulf Cooperation Council countries; review of systematic reviews, BMC PUBLIC HEALTH, Vol: 17, ISSN: 1471-2458
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Alshamsan R, Leslie H, Majeed A, et al., 2017, Financial hardship on the path to Universal Health Coverage in the Gulf States, HEALTH POLICY, Vol: 121, Pages: 315-320, ISSN: 0168-8510
Barbaric J, Abbott R, Posadzki P, et al., 2017, Light therapies for acne: abridged Cochrane systematic review including GRADE assessments., Br J Dermatol
We undertook a Cochrane review of randomized controlled trials (RCTs) evaluating the effects of light-based interventions for acne vulgaris. We searched the Cochrane Skin Specialised Register, CENTRAL, MEDLINE, Embase, LILACS, ISI Web of Science, and grey literature sources (September 2015). We used the Grading of Recommendations Assessment, Development and Evaluation Working Group approach to assess the quality of evidence (QE). We included 71 RCTs (4211 participants, median sample size 31). Results from a single study (n = 266, low QE) showed little or no difference in effectiveness on participants' assessment of improvement between 20% aminolevulinic acid (ALA) photodynamic therapy (PDT), activated by blue light, versus vehicle plus blue light, whereas another study (n = 180) of a comparison of ALA-PDT (red light) concentrations showed 20% ALA-PDT was no more effective than 15%, but better than 10% and 5% ALA-PDT. Pooled data from three studies, (n = 360, moderate QE) showed that methyl aminolevulinate (MAL)-PDT, activated by red light, had a similar effect on changes in lesion counts, compared with placebo cream with red light. Several studies compared yellow light to placebo or no treatment, infrared light to no treatment, gold-microparticle suspension to vehicle, and clindamycin/benzoyl peroxide (C/BPO) combined with pulsed dye laser to C/BPO alone. None of these showed any clinically significant effects. Most studies reported adverse effects, but inadequately, with scarring reported as absent, and blistering only in studies on intense pulsed light, infrared light and PDT (very low QE). Carefully planned studies, using standardised outcome measures, and common acne treatments as comparators are needed. This article is protected by copyright. All rights reserved.
Barber RM, Fullman N, Sorensen RJD, et al., 2017, Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the Global Burden of Disease Study 2015, LANCET, Vol: 390, Pages: 231-266, ISSN: 0140-6736
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Basetti S, Hodgson J, Rawson TM, et al., 2017, Scarlet fever: a guide for general practitioners, London Journal of Primary Care, Pages: 1-3, ISSN: 1757-1472
Belisario JSM, Doherty K, O'Donoghue J, et al., 2017, A bespoke mobile application for the longitudinal assessment of depression and mood during pregnancy: protocol of a feasibility study, BMJ OPEN, Vol: 7, ISSN: 2044-6055
Car LT, Papachristou N, Urch C, et al., 2017, Prioritizing medication safety in care of people with cancer: clinicians' views on main problems and solutions, JOURNAL OF GLOBAL HEALTH, Vol: 7, ISSN: 2047-2978
Carruthers J, Holmes A, Majeed A, 2017, A suspected viral rash in pregnancy, BMJ-BRITISH MEDICAL JOURNAL, Vol: 356, ISSN: 1756-1833
Carruthers J, Holmes A, Majeed A, 2017, Authors' reply to Mannion., BMJ, Vol: 357
Carruthers J, Holmes A, Majeed A, 2017, Incorrect information on immunoglobulin as preventive treatment for varicella Reply, BMJ-BRITISH MEDICAL JOURNAL, Vol: 357, ISSN: 1756-1833
Chang KC-M, Majeed A, Vamos EP, et al., 2017, The authors respond to "NHS Health Check: national evaluation findings and implications", CANADIAN MEDICAL ASSOCIATION JOURNAL, Vol: 189, Pages: E173-E173, ISSN: 0820-3946
Cowling TE, Harris M, Majeed A, 2017, Extended opening hours and patient experience of general practice in England: multilevel regression analysis of a national patient survey, BMJ QUALITY & SAFETY, Vol: 26, Pages: 360-371, ISSN: 2044-5415
Dieleman J, Campbell M, Chapin A, et al., 2017, Evolution and patterns of global health financing 1995-2014: development assistance for health, and government, prepaid private, and out-of-pocket health spending in 184 countries, LANCET, Vol: 389, Pages: 1981-2004, ISSN: 0140-6736
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Dieleman JL, Campbell M, Chapin A, et al., 2017, Future and potential spending on health 2015-40: development assistance for health, and government, prepaid private, and out-of-pocket health spending in 184 countries, LANCET, Vol: 389, Pages: 2005-2030, ISSN: 0140-6736
El-Osta A, Woringer M, Pizzo E, et al., 2017, Does use of point-of-care testing improve cost-effectiveness of the NHS Health Check programme in the primary care setting? A cost-minimisation analysis., BMJ Open, Vol: 7
OBJECTIVE: To determine if use of point of care testing (POCT) is less costly than laboratory testing to the National Health Service (NHS) in delivering the NHS Health Check (NHSHC) programme in the primary care setting. DESIGN: Observational study and theoretical mathematical model with microcosting approach. SETTING: We collected data on NHSHC delivered at nine general practices (seven using POCT; two not using POCT). PARTICIPANTS: We recruited nine general practices offering NHSHC and a pathology services laboratory in the same area. METHODS: We conducted mathematical modelling with permutations in the following fields: provider type (healthcare assistant or nurse), type of test performed (total cholesterol with either lab fasting glucose or HbA1c), cost of consumables and variable uptake rates, including rate of non-response to invite letter and rate of missed [did not attend (DNA)] appointments. We calculated total expected cost (TEC) per 100 invites, number of NHSHC conducted per 100 invites and costs for completed NHSHC for laboratory and POCT-based pathways. A univariate and probabilistic sensitivity analysis was conducted to account for uncertainty in the input parameters. MAIN OUTCOME MEASURES: We collected data on cost, volume and type of pathology services performed at seven general practices using POCT and a pathology services laboratory. We collected data on response to the NHSHC invitation letter and DNA rates from two general practices. RESULTS: TEC of using POCT to deliver a routine NHSHC is lower than the laboratory-led pathway with savings of £29 per 100 invited patients up the point of cardiovascular disease risk score presentation. Use of POCT can deliver NHSHC in one sitting, whereas the laboratory pathway offers patients several opportunities to DNA appointment. CONCLUSIONS: TEC of using POCT to deliver an NHSHC in the primary care setting is lower than the laboratory-led pathway. Using POCT minimises DNA rates associated with laboratory
Elmontsri M, Almashrafi A, Banarsee R, et al., 2017, Status of patient safety culture in Arab countries: a systematic review, BMJ OPEN, Vol: 7, ISSN: 2044-6055
Elmontsri M, Almashrafi A, Banarsee R, et al., 2017, Status of patient safety culture in Arab countries: a systematic review, BMJ OPEN, Vol: 7, ISSN: 2044-6055
Elmontsri M, Banarsee R, Majeed A, 2017, Key priority areas for patient safety improvement strategy in Libya: a protocol for a modified Delphi study, BMJ OPEN, Vol: 7, ISSN: 2044-6055
Hone T, Lee JT, Majeed A, et al., 2017, Does charging different user fees for primary and secondary care affect first-contacts with primary healthcare? A systematic review, HEALTH POLICY AND PLANNING, Vol: 32, Pages: 723-731, ISSN: 0268-1080
Hone T, Lee JT, Majeed A, et al., 2017, Does charging different user fees for primary and secondary care affect first-contacts with primary healthcare? A systematic review., Health Policy Plan, Vol: 32, Pages: 723-731
Policy-makers are increasingly considering charging users different fees between primary and secondary care (differential user charges) to encourage utilisation of primary health care in health systems with limited gate keeping. A systematic review was conducted to evaluate the impact of introducing differential user charges on service utilisation. We reviewed studies published in MEDLINE, EMBASE, the Cochrane library, EconLIT, HMIC, and WHO library databases from January 1990 until June 2015. We extracted data from the studies meeting defined eligibility criteria and assessed study quality using an established checklist. We synthesized evidence narratively. Eight studies from six countries met our eligibility criteria. The overall study quality was low, with diversity in populations, interventions, settings, and methods. Five studies examined the introduction of or increase in user charges for secondary care, with four showing decreased secondary care utilisation, and three showing increased primary care utilisation. One study identified an increase in primary care utilisation after primary care user charges were reduced. The introduction of a non-referral charge in secondary care was associated with lower primary care utilisation in one study. One study compared user charges across insurance plans, associating higher charges in secondary care with higher utilisation in both primary and secondary care. Overall, the impact of introducing differential user-charges on primary care utilisation remains uncertain. Further research is required to understand their impact as a demand side intervention, including implications for health system costs and on utilisation among low-income patients.
Hone T, Rasella D, Barreto M, et al., 2017, Large Reductions In Amenable Mortality Associated With Brazil's Primary Care Expansion And Strong Health Governance, HEALTH AFFAIRS, Vol: 36, Pages: 149-158, ISSN: 0278-2715
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Hone T, Rasella D, Barreto ML, et al., 2017, Association between expansion of primary healthcare and racial inequalities in mortality amenable to primary care in Brazil: A national longitudinal analysis, PLOS MEDICINE, Vol: 14, ISSN: 1549-1676
Joseph A, Cliffe C, Hillyard M, et al., 2017, Gender identity and the management of the transgender patient: a guide for non-specialists, JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, Vol: 110, Pages: 144-152, ISSN: 0141-0768
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