Publications
980 results found
Chatu S, Saxena S, Subramanian V, et al., 2014, The Impact of Timing and Duration of Thiopurine Treatment on First Intestinal Resection in Crohn's Disease: National UK Population-Based Study 1989-2010, AMERICAN JOURNAL OF GASTROENTEROLOGY, Vol: 109, Pages: 409-416, ISSN: 0002-9270
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- Citations: 54
Vamos EP, Pape UJ, Curcin V, et al., 2014, Influenza vaccine effectiveness against hospitalisation and death in people with Type 2 diabetes, Publisher: WILEY-BLACKWELL, Pages: 74-75, ISSN: 0742-3071
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- Citations: 1
Murray J, Bottle A, Sharland M, et al., 2014, Risk Factors for Hospital Admission with RSV Bronchiolitis in England: A Population-Based Birth Cohort Study, PLOS ONE, Vol: 9, ISSN: 1932-6203
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- Citations: 125
Barrera L, Leaper C, Pape UJ, et al., 2014, Impact of ethnic-specific guidelines for anti-hypertensive prescribing in primary care in England: a longitudinal study, BMC HEALTH SERVICES RESEARCH, Vol: 14
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- Citations: 3
Hopkinson NS, Majeed A, Britton J, et al., 2014, SMOKING IN CARS WITH CHILDREN Respiratory health professionals call on MPs to vote to ban smoking in cars with children, BMJ-BRITISH MEDICAL JOURNAL, Vol: 348, ISSN: 1756-1833
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- Citations: 4
Brettell R, Soljak M, Cecil E, et al., 2014, Reducing heart failure admission rates in England 2004–2011 are not related to changes in primary care quality: national observational study, European Journal of Heart Failure, Vol: 15, Pages: 1335-1342, ISSN: 1879-0844
Aims Heart failure (HF) is an important clinical problem. Expert consensus has defined HF as a primary care-sensitive condition for which the risk of unplanned admissions may be reduced by high quality primary care, but there is little supporting evidence. We analysed time trends in HF admission rates in England and risk and protective factors for admission.Methods and results We used Hospital Episodes Statistics to produce indirectly standardized HF admission counts by general practice for 2004–2011. Clustered negative binomial regression analysis produced admission risk ratios and assessed the significance of potential explanatory covariates. These included population factors (deprivation; HF, coronary heart disease, and smoking prevalence), primary care resourcing [access; general practitioner (GP) supply], and primary care quality (‘Quality and Outcomes Framework’ indicator.) There were 327 756 HF admissions of patients registered with 8405 practices over the study period. There was a significant reduction in admissions over time, from 6.96/100 000 in 2004 to 5.60/100 000 in 2010 (P < 0.001). Deprivation and HF prevalence were risk factors for admission. GP supply and access protected against admission. However, these effects were small and did not explain the large and highly significant annual trend in falling admission rates.Conclusions The observed fall in admissions over time cannot be explained by the primary care covariates we included. This analysis suggests that the potential for further significant reduction in emergency HF admissions by improving clinical quality of primary care (as currently measured) may be limited. Further work is required to identify the reasons for the reduction in admissions.
Fahrni ML, Franklin BD, Rawaf S, et al., 2014, Improving medication safety in UK care homes: challenges and current perspective, JRSM Open, Vol: 5, Pages: 1-6, ISSN: 2054-2704
In the UK, there are policy and regulatory concerns regarding the governance of care homes and healthcare provision within these homes. From a public health perspective, these issues can pose significant challenges to the provision of safe and quality medication use services to care home residents. The objective of this paper is to highlight an important and neglected issue for the growing population of institutionalized older adults. We reviewed relevant literature for the years 2000 to present and identified recent efforts undertaken to improve medication safety standards in UK care homes.We consider the limitations and reasons for the National Health Service’s restricted role and lack of leadership in providing medical services for this institutionalized population. The efforts taken by the Department of Health and other healthcare authorities targeting medication safety in care homes are also highlighted. In order to improve the quality of healthcare, specifically in areasrelated to medication safety and quality use of medicines, interventions need to be taken by the national government and similarly by local authorities and NHS commissioners.
Chhaya V, Pollok R, Cecil E, et al., 2014, Adolescent and young adults are more likely to require total colectomy in ulcerative colitis: UK population based cohort study, JOURNAL OF CROHNS & COLITIS, Vol: 8, Pages: S33-S33, ISSN: 1873-9946
Chhaya V, Saxena S, Cecil E, et al., 2014, Increasing colectomy rates over time in ulcerative colitis and the impact of thiopurines: A nationwide cohort study, JOURNAL OF CROHNS & COLITIS, Vol: 8, Pages: S53-S54, ISSN: 1873-9946
Artac M, Dalton ARH, Majeed A, et al., 2014, Re: Questionable evidence of effectiveness of a national cardiovascular disease risk assessment program, PREVENTIVE MEDICINE, Vol: 59, Pages: 84-85, ISSN: 0091-7435
Majeed A, El-Sayed AA, Khoja T, et al., 2014, Diabetes in the Middle-East and North Africa: An update, DIABETES RESEARCH AND CLINICAL PRACTICE, Vol: 103, Pages: 218-222, ISSN: 0168-8227
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- Citations: 115
Ahmad A, Laverty AA, Aasheim E, et al., 2014, Eligibility for bariatric surgery among adults in England: analysis of a national cross-sectional survey., JRSM Open, Vol: 5, ISSN: 2054-2704
OBJECTIVES: This study aimed to determine the number eligible for bariatric surgery and their sociodemographic characteristics. DESIGN: We used Health Survey for England 2006 data, representative of the non-institutionalized English population. SETTING: The number of people eligible for bariatric surgery in England based on national guidance is unknown. The UK National Institute for Health and Clinical Excellence criteria for eligibility are those with body mass index (BMI) 35-40 kg/m(2) with at least one comorbidity potentially improved by losing weight or a BMI > 40 kg/m(2). PARTICIPANTS: Of 13,742 adult respondents (≥18 years), we excluded participants with invalid BMI (n = 2103), comorbidities (n = 2187) or sociodemographic variables (n = 27) data, for a final study sample of 9425 participants. MAIN OUTCOME MEASURES: The comorbidities examined were hypertension, type 2 diabetes, stroke, coronary heart disease and osteoarthritis. Sociodemographic variables assessed included age, sex, employment status, highest educational qualification, social class and smoking status. RESULTS: 5.4% (95% CI 5.0-5.9) of the non-institutionalized adult population in England could meet criteria for having bariatric surgery after accounting for survey weights. Those eligible were more likely than the general population to be women (60.1% vs. 39.9%, p<0.01), retired (22.4% vs. 12.8% p<0.01), and have no formal educational qualifications (35.7% vs. 21.3%, p<0.01). CONCLUSIONS: The number of adults potentially eligible for bariatric surgery in England (2,147,683 people based on these results and 2006 population estimates) far exceeds previous estimates of eligibility. In view of the sociodemographic characteristics of this group, careful resource allocation is required to ensure equitable access on the basis of need.
Majeed A, 2014, Tips for dealing with the members of the Shelford Group, BMJ-BRITISH MEDICAL JOURNAL, Vol: 348, ISSN: 1756-1833
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- Citations: 1
Dalton A, Vamos E, Harris M, et al., 2014, Impact of universal coverage on hypertension management: a cross-national study in the United States and England, PLoS ONE, Vol: 9, ISSN: 1932-6203
Background: The Patient Protection and Affordable Care Act (ACA) galvanised debate in the United States (US) overuniversal health coverage. Comparison with countries providing universal coverage may illustrate whether the ACA canimprove health outcomes and reduce disparities. We aimed to compare quality and disparities in hypertensionmanagement by socio-economic position in the US and England, the latter of which has universal health care.Method: We used data from the Health and Retirement Survey in the US, and the English Longitudinal Study for Aging fromEngland, including non-Hispanic White respondents aged 50–64 years (US market-based v NHS) and .65 years (USMedicarev NHS) with diagnosed hypertension. We compared blood pressure control to clinical guideline (140/90 mmHg)and audit (150/90 mmHg) targets; mean systolic and diastolic blood pressure and antihypertensive prescribing, anddisparities in each by educational attainment, income and wealth, using regression models.Results: There were no significant differences in aggregate achievement of clinical targets aged 50 to 65 years (US marketbasedvs. NHS- 62.3% vs. 61.3% [p = 0.835]). There was, however, greater control in the US in patients aged 65 years and over(US Medicare vs. NHS- 53.5% vs. 58.2% [p = 0.043]). England had no significant socioeconomic disparity in blood pressurecontrol (60.9% vs. 63.5% [p = 0.588], high and low wealth aged $65 years). The US had socioeconomic differences in the 50–64 years group (71.7% vs. 55.2% [p = 0.003], high and low wealth); these were attenuated but not abolished in Medicarebeneficiaries.Conclusion: Moves towards universal health coverage in the US may reduce disparities in hypertension management. Thecurrent situation, providing universal coverage for residents aged 65 years and over, may not be sufficient for equality incare.
Hamilton FLH, Laverty AA, Gluvajic D, et al., 2014, Effect of financial incentives on delivery of alcohol screening and brief intervention (ASBI) in primary care: longitudinal study, Journal of Public Health
Mastellos N, Gunn LH, Felix LM, et al., 2014, Transtheoretical model stages of change for dietary and physical exercise modification in weight loss management for overweight and obese adults, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X
Tillin T, Hughes AD, Whincup P, et al., 2014, Ethnicity and prediction of cardiovascular disease: performance of QRISK2 and Framingham scores in a UK tri-ethnic prospective cohort study (SABRE-Southall And Brent REvisited), Heart, Vol: 100, Pages: 60-67, ISSN: 1355-6037
Objective To evaluate QRISK2 and Framingham cardiovascular disease (CVD) risk scores in a tri-ethnic UK population.Design Cohort study.Setting West London.Participants Randomly selected from primary care lists. Follow-up data were available for 87% of traced participants, comprising 1866 white Europeans, 1377 South Asians, and 578 African Caribbeans, aged 40–69 years at baseline (1998–1991).Main outcome measures First CVD events: myocardial infarction, coronary revascularisation, angina, transient ischaemic attack or stroke reported by participant, primary care or hospital records or death certificate.Results During follow-up, 387 CVD events occurred in men (14%) and 78 in women (8%). Both scores underestimated risk in European and South Asian women (ratio of predicted to observed risk: European women: QRISK2: 0.73, Framingham: 0.73; South Asian women: QRISK2: 0.52, Framingham: 0.43). In African Caribbeans, Framingham over-predicted in men and women and QRISK2 over-predicted in women. Framingham classified 28% of participants as high risk, predicting 54% of all such events. QRISK2 classified 19% as high risk, predicting 42% of all such events. Both scores performed poorly in identifying high risk African Caribbeans; QRISK2 and Framingham identified as high risk only 10% and 24% of those who experienced events.Conclusions Neither score performed consistently well in all ethnic groups. Further validation of QRISK2 in other multi-ethnic datasets, and better methods for identifying high risk African Caribbeans and South Asian women, are required.
Greenfield G, Ignatowicz AM, Majeed A, et al., 2014, Patient narratives on person-centeredness in the integrated care context, INTERNATIONAL JOURNAL OF INTEGRATED CARE, Vol: 14, ISSN: 1568-4156
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- Citations: 1
Soljak M, Watt H, Adomaviciute S, et al., 2014, Impact of the Northwest London Integrated Care Pilot on diabetes control, INTERNATIONAL JOURNAL OF INTEGRATED CARE, Vol: 14, ISSN: 1568-4156
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- Citations: 1
Cowling TE, Harris MJ, Soljak MA, et al., 2013, Opening hours of general practices in England, British Medical Journal, Vol: 347
Tsang C, Bottle A, Majeed A, et al., 2013, NEW CANCERS ON EMERGENCY ADMISSION Care is needed in epidemiological research not to overgeneralise about cancer diagnosis and treatment, BMJ-BRITISH MEDICAL JOURNAL, Vol: 347, ISSN: 1756-1833
van Velthoven MH, Li Y, Wang W, et al., 2013, mHealth Series: Factors influencing sample size calculations for mHealth-based studies - A mixed methods study in rural China, Journal of Global Health, Vol: 3, Pages: 70-90, ISSN: 2047-2986
Ramachandran A, Snehalatha C, Ram J, et al., 2013, Efficacy of mobile phone messaging in prevention of type 2 diabetes by lifestyle change in men at high risk - A randomised clinical trial in India, Journal of Association of Physicians of India, Vol: 61, Pages: 951-952, ISSN: 0004-5772
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- Citations: 1
van Velthoven MH, Li Y, Wang W, et al., 2013, mHealth Series: mHealth project in Zhao County, rural China - Description of objectives, field site and methods, JOURNAL OF GLOBAL HEALTH, Vol: 3, Pages: 48-69, ISSN: 2047-2978
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- Citations: 9
van Velthoven MH, Li Y, Wang W, et al., 2013, mHealth Series: Factors influencing sample size calculations for mHealth-based studies - A mixed methods study in rural China., Journal of Global Health, Vol: 3, Pages: 020404-020404, ISSN: 2047-2978
BACKGROUND: An important issue for mHealth evaluation is the lack of information for sample size calculations. OBJECTIVE: To explore factors that influence sample size calculations for mHealth-based studies and to suggest strategies for increasing the participation rate. METHODS: We explored factors influencing recruitment and follow-up of participants (caregivers of children) in an mHealth text messaging data collection cross-over study. With help of village doctors, we recruited 1026 (25%) caregivers of children under five out of the 4170 registered. To explore factors influencing recruitment and provide recommendations for improving recruitment, we conducted semi-structured interviews with village doctors. Of the 1014 included participants, 662 (65%) responded to the first question about willingness to participate, 538 (53%) responded to the first survey question and 356 (35%) completed the text message survey. To explore factors influencing follow-up and provide recommendations for improving follow-up, we conducted interviews with participants. We added views from the researchers who were involved in the study to contextualize the findings. RESULTS: WE FOUND SEVERAL FACTORS INFLUENCING RECRUITMENT RELATED TO THE FOLLOWING THEMES: experiences with recruitment, village doctors' work, village doctors' motivations, caregivers' characteristics, caregivers' motivations. Village doctors gave several recommendations for ways to recruit more caregivers and we added our views to these. We found the following factors influencing follow-up: mobile phone usage, ability to use mobile phone, problems with mobile phone, checking mobile phone, available time, paying back text message costs, study incentives, subjective norm, culture, trust, perceived usefulness of process, perceived usefulness of outcome, perceived ease of use, attitude, behavioural intention to use, and actual use. From our perspective, factors influencing follow-up were: different caregivers participating in f
Brettell R, Soljak M, Cecil E, et al., 2013, Reducing heart failure admission rates in England 20042011 are not related to changes in primary care quality: national observational study, EUROPEAN JOURNAL OF HEART FAILURE, Vol: 15, Pages: 1335-1342, ISSN: 1388-9842
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- Citations: 26
Cowling TE, Ramzan F, Majeed A, et al., 2013, Attendances at Charing Cross and Hammersmith Hospitals’ urgent care centres, 2009-12, BMJ, Vol: 347
Majeed A, 2013, STATINS FOR LOW RISK DISEASE Increasing the use of statins in people at low cardiovascular risk is difficult, BMJ-BRITISH MEDICAL JOURNAL, Vol: 347, ISSN: 1756-1833
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- Citations: 1
Majeed A, 2013, ALLOCATION OF NHS RESOURCES Life expectancy at birth and at age 65 for local areas in England and Wales, BMJ-BRITISH MEDICAL JOURNAL, Vol: 347, ISSN: 1756-1833
Ramachandran A, Snehalatha C, Ram J, et al., 2013, Effectiveness of mobile phone messaging in prevention of type 2 diabetes by lifestyle modification in men in India: a prospective, parallel-group, randomised controlled trial, The Lancet Diabetes & Endocrinology, Vol: 1, Pages: 191-198, ISSN: 2213-8587
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