Imperial College London

PROFESSOR AZEEM MAJEED

Faculty of MedicineSchool of Public Health

Chair - Primary Care and Public Health & Head of Department
 
 
 
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Contact

 

+44 (0)20 7594 3368a.majeed Website

 
 
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Assistant

 

Ms Dorothea Cockerell +44 (0)20 7594 3368

 
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Location

 

Reynolds BuildingCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Feigin:2017:10.1016/S1474-4422(17)30299-5,
author = {Feigin, VL and Abajobir, AA and Abate, KH and et, al and Rawaf, S and Vos, T and GBD, 2015 Neurological Disorders Collaborator Group},
doi = {10.1016/S1474-4422(17)30299-5},
journal = {Lancet Neurology},
pages = {877--897},
title = {Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015},
url = {http://dx.doi.org/10.1016/S1474-4422(17)30299-5},
volume = {16},
year = {2017}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - BackgroundComparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this systematic analysis, we quantified the global disease burden due to neurological disorders in 2015 and its relationship with country development level.MethodsWe estimated global and country-specific prevalence, mortality, disability-adjusted life-years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) for various neurological disorders that in the GBD classification have been previously spread across multiple disease groupings. The more inclusive grouping of neurological disorders included stroke, meningitis, encephalitis, tetanus, Alzheimer's disease and other dementias, Parkinson's disease, epilepsy, multiple sclerosis, motor neuron disease, migraine, tension-type headache, medication overuse headache, brain and nervous system cancers, and a residual category of other neurological disorders. We also analysed results based on the Socio-demographic Index (SDI), a compound measure of income per capita, education, and fertility, to identify patterns associated with development and how countries fare against expected outcomes relative to their level of development.FindingsNeurological disorders ranked as the leading cause group of DALYs in 2015 (250·7 [95% uncertainty interval (UI) 229·1 to 274·7] million, comprising 10·2% of global DALYs) and the second-leading cause group of deaths (9·4 [9·1 to 9·7] million], comprising 16·8% of global deaths). The most prevalent neurological disorders were tension-type headache (1505·9 [UI 1337·3 to 1681·6 million cases]), migraine (958·8
AU - Feigin,VL
AU - Abajobir,AA
AU - Abate,KH
AU - et,al
AU - Rawaf,S
AU - Vos,T
AU - GBD,2015 Neurological Disorders Collaborator Group
DO - 10.1016/S1474-4422(17)30299-5
EP - 897
PY - 2017///
SN - 1474-4422
SP - 877
TI - Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
T2 - Lancet Neurology
UR - http://dx.doi.org/10.1016/S1474-4422(17)30299-5
UR - http://hdl.handle.net/10044/1/50963
VL - 16
ER -