Imperial College London
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ProfessorAlisonMcGregor

Faculty of Medicine, Department of Surgery & Cancer

Professor of Musculoskeletal Biodynamics
 
 
 
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Contact

 

+44 (0)20 7594 2972a.mcgregor

 
 
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Location

 

Room 202ASir Michael Uren HubWhite City Campus

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Summary

 

Publications

Publication Type
Year
to

288 results found

Buckeridge EM, Bull AMJ, Mcgregor AH, 2014, Foot force production and asymmetries in elite rowers, SPORTS BIOMECHANICS, Vol: 13, Pages: 47-61, ISSN: 1476-3141

Journal article

Varma RK, Duffell LD, Nathwani D, McGregor AHet al., 2014, Knee moments of anterior cruciate ligament reconstructed and control participants during normal and inclined walking, BMJ OPEN, Vol: 4, ISSN: 2044-6055

Journal article

Spulber I, Papi E, Chen Y-M, Anastasova-Ivanova S, Bergmann J, Georgiou P, McGregor AHet al., 2014, Development of a wireless multi-functional body sensing platform for smart garment integration, IEEE Biomedical Circuits and Systems Conference (BioCAS), Publisher: IEEE, Pages: 157-160, ISSN: 2163-4025

Conference paper

McGregor AH, Dore CJ, Morris TP, 2013, An exploration of patients' expectation of and satisfaction with surgical outcome, European Spine Journal, Vol: 22, Pages: 2836-2844, ISSN: 1432-0932

Purpose The majority of studies of surgical outcomefocus on measures of function and pain. Increasingly,however, the desire to include domains such as patients’satisfaction and expectations had led to the development ofsimple measures and their inclusion into clinical studies.The purpose of this study was to determine patients’ preoperativeexpectations of and post-operative satisfactionwith the outcome of their spinal surgery.Methods As part of the FASTER randomised controlledtrial, patients were asked pre-operatively to quantify theirexpected improvement in pain and health status at 6 weeks,6 and 12 months following surgery using 100 mm visualanalogue scales (VAS), and to indicate their confidence inachieving this result and also the importance of thisrecovery to them. Patients were then asked to rate theirsatisfaction with the improvement achieved at each postoperativereview using 100 mm VAS.Results Although differences between patients’ expectationand achievement were minimal 6 weeks post-operatively,there was a clear discrepancy at 6 months and1 year, with patient expectations far exceeding achievement.There were significant correlations between failure toachieve expectations and the importance patients attachedto this recovery at each post-operative assessment, but notwith their confidence in achieving this result. Satisfactionlevels remained high despite expectations not being met,with discectomy patients being more satisfied thandecompression patients.Conclusions Patients’ pre-operative expectations of surgicaloutcome exceed their long-term achievement. Themore importance the patient attached to a good outcome,the larger is the discrepancy between expectation andachievement. Despite this, satisfaction levels remainedhigh. The impact of unrealistic expectations on outcomeremains unclear.

Journal article

Bergmann JHM, Anastasova-Ivanova S, Spulber I, Gulati V, Georgiou P, McGregor Aet al., 2013, An Attachable Clothing Sensor System for Measuring Knee Joint Angles, IEEE SENSORS JOURNAL, Vol: 13, Pages: 4090-4097, ISSN: 1530-437X

Journal article

Borhani M, McGregor AH, Bull AMJ, 2013, An alternative technical marker set for the pelvis is more repeatable than the standard pelvic marker set, Gait and Posture, Vol: 38, Pages: 1032-1037, ISSN: 0966-6362

Multiple marker sets and models are currently available for assessing pelvic kinematics in gait. Despite the presence of a variety models, there are still debates on their reliability and consistency, and consequently there is no clearly defined standard. Two marker sets were evaluated in this study: the ‘Traditional’ where markers are placed at the anterior and posterior superior iliac spines (ASISs, PSISs); and the ‘Cluster’, where a cluster of three orthogonal markers fixed on a rigid based is attached to the sacrum. The two sets were compared with respect to intra and inter session standard deviations of maximum pelvic tilt, obliquity and rotation angles. The repeatability between and within sessions was measured using coefficient of multiple correlation (CMC). Also the similarity between the two sets was assessed using inter-protocol CMC (ipCMC). Both data sets generated showed high within and between session repeatability in the sagittal plane (CMC > 0.80), although the Cluster method showed higher repeatability than that of the Traditional method in non-sagittal plane motion for both within and between sessions. The authors are not aware of other studies reporting the differences in intra and inter session variability and repeatability values for different body mass index categories such as overweight and obese subjects with relatively large sample size. Hence the Cluster method overcomes a number of theoretical and experimental limitations such as minimising the marker occlusion and is a reliable alternative to the Traditional (the standard) marker set.

Journal article

Duffell LD, Gulati V, Southgate DFL, McGregor AHet al., 2013, Measuring body weight distribution during sit-to-stand in patients with early knee osteoarthritis, GAIT & POSTURE, Vol: 38, Pages: 745-750, ISSN: 0966-6362

Journal article

Bergmann JHM, Graham S, Howard N, McGregor Aet al., 2013, Comparison of median frequency between traditional and functional sensor placements during activity monitoring, MEASUREMENT, Vol: 46, Pages: 2193-2200, ISSN: 0263-2241

Journal article

Pincus T, Anwar S, McCracken L, McGregor A, Graham L, Collinson M, Farrin AJet al., 2013, Testing the credibility, feasibility and acceptability of an optimised behavioural intervention (OBI) for avoidant chronic low back pain patients: protocol for a randomised feasibility study, TRIALS, Vol: 14, ISSN: 1745-6215

Journal article

Wang P, Low KH, McGregor AH, Tow Aet al., 2013, Detection of abnormal muscle activations during walking following spinal cord injury (SCI), RESEARCH IN DEVELOPMENTAL DISABILITIES, Vol: 34, Pages: 1226-1235, ISSN: 0891-4222

Journal article

Duffell L, Alexander C, Greenwood N, McGregor Aet al., 2013, Re: Electromyographic activity of pelvic and lower limb muscles during postural tasks in people with benign joint hypermobility syndrome and non hypermobile people. A pilot study Greenwood NL, Duffell LD, Alexander CM & McGregor AH. Man Ther 2011;16:p. 623-628, MANUAL THERAPY, Vol: 18, Pages: E10-E10, ISSN: 1356-689X

Journal article

Nicotra A, King NKK, Catley M, Mendoza N, McGregor AH, Strutton PHet al., 2013, Evaluation of corticospinal excitability in cervical myelopathy, before and after surgery, with transcranial magnetic stimulation: a pilot study, EUROPEAN SPINE JOURNAL, Vol: 22, Pages: 189-196, ISSN: 0940-6719

Journal article

McGregor AH, Probyn K, Cro S, Dore CJ, Burton AK, Balague F, Pincus T, Fairbank Jet al., 2013, Rehabilitation following surgery for lumbar spinal stenosis, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X

Journal article

Bergmann JHM, Chandaria V, McGregor A, 2012, Wearable and Implantable Sensors: The Patient's Perspective, SENSORS, Vol: 12, Pages: 16695-16709, ISSN: 1424-8220

Journal article

Buckeridge E, Hislop S, Bull A, McGregor Aet al., 2012, Kinematic Asymmetries of the Lower Limbs during Ergometer Rowing, MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, Vol: 44, Pages: 2147-2153, ISSN: 0195-9131

Journal article

Hughes SPF, Freemont AJ, Hukins DWL, McGregor AH, Roberts Set al., 2012, The pathogenesis of degeneration of the intervertebral disc and emerging therapies in the management of back pain, JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, Vol: 94B, Pages: 1298-1304, ISSN: 0301-620X

Journal article

McGregor AH, Henley A, Morris TP, Dore CJet al., 2012, Patients' views on an education booklet following spinal surgery, European Spine Journal, Vol: 21, Pages: 1609-1615, ISSN: 1432-0932

Purpose This study evaluated an evidence-based educationbooklet developed for patients undergoing spinal surgerywhich was used as a treatment intervention in a multi-centre,factorial, randomised controlled trial (FASTER: Functionafter spinal treatment, exercise and rehabilitation) investigatingthe post-operative management of spinal surgerypatients. This study sought to determine the acceptability andcontent of the booklet to patients.Methods Patients receiving the educational bookletbefore discharge from hospital as part of the FASTERstudy were asked to complete an evaluation, which ratedthe booklet ‘‘Your Back Operation’’ with regard to content,information, usability, etc. using forced and open questions.This assessment was conducted at the same time asthe initial 6-week post-operative review performed as partof the larger study.Results Therefore, 97% of the 117 trial participants whoreturned their 6-week evaluation and randomised to receivea booklet returned their questionnaire. The booklet washighly rated receiving an overall rating of 7 or more out of10 from 101/111 (91%), and high ratings for content,readability and information. The booklet’s key messageswere clear to the majority of patients; however, manypatients highlighted deficiencies with respect to contentparticularly in relation to wound care and exercise.Conclusions Patients valued the booklet and rated itscontent highly. Many suggested that the booklet bedeveloped further and there was a clear desire for specificexercises to be included even though there is no evidenceto support specific exercise prescription.

Journal article

McGregor AH, O'Dowd J, 2012, Introducing the Society for Back Pain Research, EUROPEAN SPINE JOURNAL, Vol: 21, Pages: S153-S153, ISSN: 0940-6719

Journal article

McGregor AH, Henley A, Morris TP, Dore CJet al., 2012, An Evaluation of a Postoperative Rehabilitation Program After Spinal Surgery and Its Impact on Outcome, SPINE, Vol: 37, Pages: E417-E422, ISSN: 0362-2436

Journal article

Dayan O, Spulber I, Eftekhar A, Georgiou P, Bergmann J, McGregor Aet al., 2012, Applying EMG spike and peak counting for a real-time muscle fatigue monitoring system, Pages: 41-44

Conference paper

Spulber I, Georgiou P, Eftekhar A, Toumazou C, Duffell L, Bergmann J, McGregor A, Mehta T, Burdett Aet al., 2012, Frequency analysis of wireless accelerometer and EMG sensors data: Towards discrimination of normal and asymmetric walking pattern, Circuits and Systems (ISCAS), 2012 IEEE International Symposium on, Pages: 2645-2648

This preliminary study reports on the combined use of wireless accelerometers and wireless EMG sensors for monitoring walking patterns. The sensor data was analyzed in frequency domain through FFT, PSD and time-frequency spectrogram analysis. Accelerometer spectra was found to shift towards lower frequencies (<3 Hz) while EMG spectra of selected muscles shifted towards higher frequencies (>50 Hz) during asymmetric walking. Median frequency was used to quantify the spectral shifts. The combined wireless accelerometer/EMG system showed potential for discrimination between the normal and asymmetric walking.

Conference paper

McGregor AH, Dore CJ, Morris TP, Morris S, Jamrozik Ket al., 2011, ISSLS Prize Winner: Function After Spinal Treatment, Exercise, and Rehabilitation (FASTER) A Factorial Randomized Trial to Determine Whether the Functional Outcome of Spinal Surgery Can Be Improved, SPINE, Vol: 36, Pages: 1711-1720, ISSN: 0362-2436

Journal article

Morris S, Morris TP, McGregor AH, Dore CJ, Jamrozik Ket al., 2011, Function After Spinal Treatment, Exercise, and Rehabilitation <i>Cost</i>-<i>Effectiveness Analysis Based on a Randomized Controlled Trial</i>, SPINE, Vol: 36, Pages: 1807-1814, ISSN: 0362-2436

Journal article

Bergmann JHM, McGregor AH, 2011, Body-Worn Sensor Design: What Do Patients and Clinicians Want?, ANNALS OF BIOMEDICAL ENGINEERING, Vol: 39, Pages: 2299-2312, ISSN: 0090-6964

Journal article

Greenwood NL, Duffell LD, Alexander CM, McGregor AHet al., 2011, Electromyographic activity of pelvic and lower limb muscles during postural tasks in people with benign joint hypermobility syndrome and non hypermobile people. A pilot study, Man Ther

Benign joint hypermobility syndrome (BJHS) is associated with the early development of certain degenerative conditions, which may be associated with altered muscle activity. This pilot study compared muscle activation patterns during postural tasks between people with BJHS who do not have pain and people with normal flexibility (control group). Sixteen subjects aged 22-45 years (8 with BJHS) were selected from a population recruited to a larger study. Electromyographic activity of erector spinae (ES), gluteus medius (GM), and lower limb (rectus femoris (RF), semitendinosus (ST), tibialis anterior (TA) and gastrocnemius lateralis) muscles was assessed, and chosen based on the muscles being tested in the larger study. Subjects carried out 30 s of quiet standing (QS) and one-leg standing (OLS), both with eyes open (EO) and eyes closed (EC). Both groups had significantly more TA activity, and control subjects had significantly more GM activity, during OLS EC compared with QS. GM activity was not significantly different between groups. Compared with the BJHS group, control subjects had significantly less ST activation overall, significantly more ES activity during OLS EC and significantly less RF-ST co-contraction during QS. This study has noted differences in muscle activation patterns between pain-free hypermobile people and control subjects, specifically involving muscles surrounding the pelvis and hip. This pilot data suggests that strategies for stabilising the body during balancing tasks may be relevant to injury risk in people with BJHS. While results need to be verified with a larger subject sample, this study is important in developing new treatments for hypermobile people

Journal article

Murphy AJ, Bull AMJ, McGregor AH, 2011, Optimizing and validating an electromagnetic tracker in a human performance laboratory, PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, Vol: 225, Pages: 343-351, ISSN: 0954-4119

Journal article

Ali I, Ulbricht C, McGregor AH, 2011, Degeneration of the extensor muscle group in a surgical low back and leg pain population, JOURNAL OF BACK AND MUSCULOSKELETAL REHABILITATION, Vol: 24, Pages: 23-30, ISSN: 1053-8127

Journal article

Cao S, Bharath A, Parker K, Ng J, Arnold J, McGregor A, Hill Aet al., 2011, Joint Spatio-Temporal Registration and Microvasculature Segmentation of Retinal Angiogram Sequences, 2011 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), Pages: 2618-2621, ISSN: 1557-170X

Journal article

Wang P, Low KH, McGregor AH, 2011, A Subject-based Motion Generation Model with Adjustable Walking Pattern for a Gait Robotic Trainer: <i>NaTUre-gaits</i>, 2011 IEEE/RSJ INTERNATIONAL CONFERENCE ON INTELLIGENT ROBOTS AND SYSTEMS, ISSN: 2153-0858

Journal article

Duffell LD, Dharni H, Strutton PH, McGregor AHet al., 2011, Electromyographic activity of the quadriceps components during the final degrees of knee extension, JOURNAL OF BACK AND MUSCULOSKELETAL REHABILITATION, Vol: 24, Pages: 215-223, ISSN: 1053-8127

Journal article

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