Imperial College London
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ProfessorAlisonMcGregor

Faculty of Medicine, Department of Surgery & Cancer

Professor of Musculoskeletal Biodynamics
 
 
 
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Contact

 

+44 (0)20 7594 2972a.mcgregor

 
 
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Location

 

Room 202ASir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Bates:2021:10.1186/s12891-021-03961-y,
author = {Bates, A and McGregor, A and Alexander, C},
doi = {10.1186/s12891-021-03961-y},
journal = {BMC Musculoskeletal Disorders},
title = {Adaptation of balance reactions following anterior perturbations in people with Joint Hypermobility Syndrome},
url = {http://dx.doi.org/10.1186/s12891-021-03961-y},
volume = {22},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundJoint Hypermobility Syndrome (JHS) is a Heritable Disorder of Connective tissue characterised by joint laxity and chronic widespread arthralgia. People with JHS exhibit a range of other symptoms including balance problems. To explore balance further, the objective of this study is to compare responses to forward perturbations between three groups; people who are hypermobile with (JHS) and without symptoms and people with normal flexibility.MethodsTwenty-one participants with JHS, 23 participants with Generalised Joint Hypermobility (GJH) and 22 participants who have normal flexibility (NF) stood on a platform that performed 6 sequential, sudden forward perturbations (the platform moved to the anterior to the participant). Electromyographic outcomes (EMG) and kinematics for the lower limbs were recorded using a Vicon motion capture system. Within and between group comparisons were made using Kruskal Wallis tests.ResultsThere were no significant differences between groups in muscle onset latency. At the 1st perturbation the group with JHS had significantly longer time-to-peak amplitude than the NF group in tibialis anterior, vastus medialis, rectus femoris, vastus lateralis, and than the GJH group in the gluteus medius. The JHS group showed significantly higher cumulative joint angle (CA) than the NF group in the hip and knee at the 1st and 2nd and 6th perturbation, and in the ankle at the 2nd perturbation. Participants with JHS had significantly higher CA than the GJH group at the in the hip and knee in the 1st and 2nd perturbation. There were no significant differences in TTR.ConclusionsThe JHS group were able to normalise the timing of their muscular response in relation to control groups. They were less able to normalise joint CA, which may be indicative of impaired balance control and strength, resulting in reduced stability.
AU  - Bates,A
AU  - McGregor,A
AU  - Alexander,C
DO  - 10.1186/s12891-021-03961-y
PY  - 2021///
SN  - 1471-2474
TI  - Adaptation of balance reactions following anterior perturbations in people with Joint Hypermobility Syndrome
T2  - BMC Musculoskeletal Disorders
UR  - http://dx.doi.org/10.1186/s12891-021-03961-y
UR  - http://hdl.handle.net/10044/1/86412
VL  - 22
ER  -
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